anti-Malic Enzyme Complex, Mitochondrial (Mod2) 抗体

The membrane-associated protein encoded by Mod2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. 再加上,我们可以发Malic Enzyme Complex, Mitochondrial 蛋白 (2)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
小鼠 Mod2 Mod2 110357  
Mod2 5243 P08183
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通过反应活性、应用领域、克隆类型和共轭标记 Mod2 抗体

特性 应用范围 宿主 克隆类型 标记
Human , ,


,

更多抗Malic Enzyme Complex, Mitochondrial的相互作用对抗体

Human Malic Enzyme Complex, Mitochondrial (Mod2) interaction partners

  1. ABCB1 (显示 ABCB1 抗体) genotype is not a significant determinant of interindividual variability in dabigatran and rivaroxaban pharmacokinetics

  2. High MDR1 (显示 TBC1D9 抗体) expression is associated with multidrug resistance in breast cancer.

  3. inhibition of autophagy led to the decrease in stemness, restoration of mitochondrial proteins and reduced expression of CD44 (显示 CD44 抗体), ABCB1 (显示 ABCB1 抗体) and ADAM17 (显示 ADAM17 抗体)

  4. The T-allele of ABCB1 (显示 ABCB1 抗体)-C3435T gene polymorphism has demonstrated to be a good prognosis factor for resistance, progression free survival and overall survival in HER2 (显示 ERBB2 抗体)-positive Breast Cancer patients.

  5. we review the emerging role of molecular dynamics simulation techniques in our understanding of the membrane-embedded conformation of P-gp (显示 ABCB4 抗体)--{REVIEW}

  6. Studied ABCB1 (显示 ABCB1 抗体) protein expression immunohistochemically in twelve human post-mortem brain regions known to play a role in schizophrenia, in 13 patients with schizophrenia and nine controls; found a significantly reduced density of ABCB1 (显示 ABCB1 抗体)-expressing neurons in the left habenula.

  7. Using an integrated pathway-based approach, we identified polymorphisms in ABCC6 (显示 ABCC6 抗体), ABCB1 (显示 ABCB1 抗体) and CYP2C8 (显示 CYP2C8 抗体) associated with overall survival. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in Ewing sarcoma

  8. The authors found that transient TUBB3 (显示 TUBB3 抗体) activation, through ABCB1 (显示 ABCB1 抗体), in response to the stimulation of FOXO3a (显示 FOXO3 抗体) expression, significantly contributes to the cross-resistance of the paclitaxel-resistant cell population and consequently limits the efficacy of both agents where cancer cells have developed multiple resistance.

  9. MDR1 (显示 TBC1D9 抗体) and CYP3A5 (显示 CYP3A5 抗体) genetic polymorphisms significantly influence plasma trough levels and therapeutic response of imatinib in patients with chronic myeloid leukemia (显示 BCL11A 抗体). Patients with GG genotype for CYP3A5 (显示 CYP3A5 抗体)-A6986G (P=0.016) and TT genotype for MDR1 (显示 TBC1D9 抗体)-C3435T (P=0.013) polymorphisms had significantly higher trough levels of imatinib.

  10. Rescue experiments confirmed the combined role of LUCAT1, miR (显示 MLXIP 抗体)-200c and ABCB1 (显示 ABCB1 抗体) on osteosarcoma proliferation, invasion and methotrexate resistance. Overall, results indicate the vital role of LUCAT1 in the methotrexate resistance regulation through miR (显示 MLXIP 抗体)-200c/ABCB1 (显示 ABCB1 抗体) pathway, providing a novel insight and treatment strategy for osteosarcoma drug resistance.

Malic Enzyme Complex, Mitochondrial (Mod2) 抗原简介

蛋白简介

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with Mod2

  • malic enzyme complex, mitochondrial (Mod2) 抗体
  • ATP binding cassette subfamily B member 1 (ABCB1) 抗体
  • ABC20 抗体
  • CD243 抗体
  • CLCS 抗体
  • GP170 抗体
  • Mdr 抗体
  • Mdr-1 抗体
  • MDR1 抗体
  • Mod-2 抗体
  • Mod-2r 抗体
  • Mod-2s 抗体
  • Mod2-r 抗体
  • Mod2-s 抗体
  • P-GP 抗体
  • PGY1 抗体

Protein level used designations for Mod2

malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1

GENE ID SPECIES
110357 Mus musculus
5243 Homo sapiens
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