anti-MAGE-Like 2 (MAGEL2) 抗体

MAGEL2 is a member of the MAGEA gene family. 再加上,我们可以发MAGE-Like 2 蛋白 (2)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID
MAGEL2 54551
MAGEL2 27385
MAGEL2 679875
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • 在线下订单

antibodies-online.cn销售最多的anti-MAGE-Like 2 抗体

Showing 10 out of 45 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-MAGEL2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>A549 cell lysate WB Suggested Anti-MAGEL2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: A549 cell lysate 100 μL Log in to see 2至3个工作日
非结合性 IHC (p), WB MAGEL2 Antibody (D514) (ABIN390122) western blot analysis in K562 cell line lysates (35 µg/lane).This demonstrates the MAGEL2 antibody detected the MAGEL2 protein (arrow). MAGEL2 Antibody (C-term) (ABIN390122)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10至11个工作日
非结合性 EIA, IHC (p), WB 0.4 mL Log in to see 6至8个工作日
Cow 非结合性 WB 50 μg Log in to see 7至9个工作日
非结合性 EIA, IHC (p) 50 μg Log in to see 6至8个工作日
非结合性 IHC (p), ELISA Human Placenta (formalin-fixed, paraffin-embedded) stained with MAGEL2 antibody ABIN214669 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7至9个工作日
非结合性 IHC (p), IHC, ELISA Immunohistochemistry-Paraffin: MAGEL2 Antibody [NBP1-02509] - Staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 0.05 mg Log in to see 7至9个工作日
Alexa Fluor 488 IF (p)   100 μL Log in to see 14至21个工作日
Alexa Fluor 647 IF (p)   100 μL Log in to see 14至21个工作日
Alexa Fluor 350 IF (p)   100 μL Log in to see 14至21个工作日

通过反应活性、应用领域、克隆类型和共轭标记 MAGEL2 抗体

特性 应用范围 宿主 克隆类型 标记
Human , , ,

, , , , , , , , , , , , , , , ,
Mouse (Murine) , , ,

, , , , , , , , , , , , ,
Rat (Rattus) , , ,

, , , , , , , , , , , , ,

更多抗MAGE-Like 2的相互作用对抗体

Human MAGE-Like 2 (MAGEL2) interaction partners

  1. This study provides strong evidence for the pathogenicity of truncating mutations of the paternal allele of MAGEL2, refines the associated clinical phenotypes, and highlights implications for genetic counseling for affected families

  2. A similar pro (显示 LEP 抗体)gressive loss of leptin sensitivity caused by loss of MAGEL2 in children with Prader-Willi s (显示 LEP 抗体)yndrome could ex (显示 POMC 抗体)plain the delayed onset of increased appetite and weight gain in this complex disorder.

  3. Truncating Mutations of MAGEL2, a Gene within the Prader-Willi Locus, Are Responsible for Severe Arthrogryposis.

  4. MAGEL2 is a new gene causing complex autism spectrum disorder and MAGEL2 loss of function can contribute to several aspects of the Prader-Willi syndrome phenotype.

  5. These findings provide a cellular and molecular function for MAGE-L2-TRIM27 (显示 RFP 抗体) in retrograde transport, including an unappreciated role of K63-linked ubiquitination and identification of an activating signal of the WASH regulatory complex.

  6. Results suggest that MAGEL2 may not play a role in the pathophysiology of schizophrenia and mood disorders in the Japanese population.

  7. MAGEL2 gene is imprinted, with preferential expression from the paternal allele.

Pig (Porcine) MAGE-Like 2 (MAGEL2) interaction partners

  1. Moreover, -712C>G and -708T>C had significant effects on MAGEL2 transcription and placental efficiency

  2. Imprinting analysis showed that NDN (显示 NDN 抗体) and MAGEL2 are paternally expressed in all tissues of pig where the genes were expressed as in human and mouse.

Mouse (Murine) MAGE-Like 2 (MAGEL2) interaction partners

  1. We detected fundamental deficits in the Magel2-null brain, including global decreases in catecholamine and indolamine pathway biogenic amines, with the catecholamine pathway most affected in the hindbrain and hypothalamus.

  2. Magel2 knockout mice displayed altered social phenotype and a lack of preference for social novelty.

  3. these findings suggest that a loss of Magel2 leads to the disruption of hypothalamic feeding circuits, an effect that appears to be independent of the neurodevelopmental effects of leptin (显示 LEP 抗体) and ghrelin (显示 GHRL 抗体) and likely involves a direct neurotrophic effect of Magel2.

  4. Normal leptin (显示 LEP 抗体) responses were found in Magel2-null mice up to 4 weeks of age, but the proportion of leptin (显示 LEP 抗体)-responsive POMC (显示 POMC 抗体) neurons was reduced in 6-week-old Magel2-null mice.

  5. Magel2 inactivation induces a deficit in social recognition and social interaction and a reduced learning ability in adult male mice.

  6. This neural defect, together with increased fat mass, blunted circadian rhythm, and growth hormone (显示 GH1 抗体) response pathway defects that are also linked to loss of MAGEL2, could contribute to the hyperphagia and obesity that are hallmarks of this disorder.

  7. This study demonstrated that Magel2-null mice have abnormalities of hypothalamic endocrine axes that recapitulate phenotypes in Prader-Willi syndrome.

  8. Magel2-deficient mouse with 50% neonatal mortality had an altered onset of suckling activity and subsequent impaired feeding.

  9. Magel2 gene is imprinted, with preferential expression from the paternal allele in mouse and human.

  10. role of the circadian rhythm output gene Magel2 in brain structure and behavior

MAGE-Like 2 (MAGEL2) 抗原简介


Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.

Gene names and symbols associated with anti-MAGE-Like 2 (MAGEL2) 抗体

  • MAGE family member L2 (MAGEL2) 抗体
  • melanoma antigen, family L, 2 (Magel2) 抗体
  • MAGE family member L2 (Magel2) 抗体
  • Mage-l2 抗体
  • MAGEL2 抗体
  • NDNL1 抗体
  • nM15 抗体
  • ns7 抗体

Protein level used designations for anti-MAGE-Like 2 (MAGEL2) 抗体

MAGE-like protein 2 , necdin-like protein 1 , protein nM15 , MAGE-like 2 , melanoma antigen-like gene 2 , necdin-like 1 , protein nS7 , melanoma antigen, family L, 2

54551 Homo sapiens
538665 Bos taurus
719760 Macaca mulatta
100154924 Sus scrofa
100343334 Oryctolagus cuniculus
27385 Mus musculus
679875 Rattus norvegicus
100684492 Canis lupus familiaris
anti-MAGE-Like 2 (MAGEL2) 抗体 精选生产商