Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1) ELISA试剂盒

Human Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1) interaction partners

1. MiR (显示 MLXIP ELISA试剂盒)-183 overexpression promoted radioresistance of glioblastoma via down-regulating LRIG1 and increasing the activity of EFGR (显示 EGFR ELISA试剂盒)/Akt (显示 AKT1 ELISA试剂盒).

2. LRIG1 is a negative regulator of RET2A and RET2B and is also downregulated in papillary and medullary thyroid carcinoma

3. LRIG1 expression in human GC tissues is inversely correlated with miR (显示 MLXIP ELISA试剂盒)-20a and EGFR (显示 EGFR ELISA试剂盒).

4. Role of LRIG1 in cancer [review]

5. LRIG1 expression may represent a barrier to EMT (显示 ITK ELISA试剂盒)

6. LRIG1 role in the atrophic epidermis

7. Downregulation of LRIG1 expression in oral verrucous carcinoma tissue is reported.

8. LRIG1, as a negative mediated gene of tumor, can inhibit biological function of PAs (显示 PASK ELISA试剂盒) via inhibiting PI3K (显示 PIK3CA ELISA试剂盒)/AKT (显示 AKT1 ELISA试剂盒) and Ras/Raf (显示 RAF1 ELISA试剂盒)/ERK (显示 EPHB2 ELISA试剂盒) pathways, and it might be a new target for gene therapy ofPituitary adenomas

9. LRIG1 and Fascin-1 (显示 FSCN1 ELISA试剂盒) were differently expressed in cancer and normal lung tissue in patients with NSCLC, which could be a biomarker for mediastinal lymph node metastasis in NSCLC patients.

10. Results suggest that the LRIG1could negatively control MRP-1 (显示 MDM4 ELISA试剂盒) and the apoptosis to improve the sensitivity of VP16-related chemotherapy.

Mouse (Murine) Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1) interaction partners

1. Lrig1 marks gastric corpus epithelial progenitor cells capable of repopulating the damaged oxyntic mucosa by differentiating into normal gastric lineage cells in mouse stomach.

2. findings reveal a novel and essential role of Lrig1 in regulating morphogenic events that shape the hippocampal circuits and establish that the assembly of TrkB (显示 NTRK2 ELISA试剂盒) with Lrig1 represents a key mechanism for understanding how specific neuronal populations expand the repertoire of responses to BDNF (显示 BDNF ELISA试剂盒) during brain development

3. LRIG1 role in the atrophic epidermis

4. LRIG1+ cells were found to re-populate the neo-epidermis on day 14, suggesting an important homeostatic role of LRIG1 in skin

5. a subset of human duodenal tumors exhibited features of LRIG1(-/-) adenomas, including loss of LRIG1, gastric metaplasia (MUCIN5AC and MUCIN6), and increased amphiregulin (显示 AREG ELISA试剂盒) and Egfr (显示 EGFR ELISA试剂盒) activity.

6. LRIG1 regulates the postnatal development of ICC-DMP and ICC-SMP from smooth muscle progenitors in mice.

7. Loss of one Apc (显示 APC ELISA试剂盒) allele in Lrig1(+) cells results in inducible stem cell-driven model that recapitulates features of familial adenomatous polyposis.

8. At later stages, Lrig1 expression is sustained in non-sensory tissues, whereas Lrig2 levels are enhanced in neurons and sensory epithelia.

9. LRIG1 orchestrates corneal-tissue transparency and cell fate during repair via STAT3 (显示 STAT3 ELISA试剂盒).

10. A review summarizes the data that LRIG1 is a ERBB (显示 EGFR ELISA试剂盒) negative regulator and tumour suppressor.