LIM Domain Kinase 2 (LIMK2) ELISA试剂盒

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. 再加上,我们可以发LIMK2 抗体 (135)LIMK2 蛋白 (10)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
LIMK2 3985 P53671
LIMK2 29524 P53670
LIMK2 16886 O54785
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0.78-50 ng/mL   96 Tests Log in to see 2至3个工作日
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适于 LIMK2 相互作用对的更多 ELISA 试剂盒

Human LIM Domain Kinase 2 (LIMK2) interaction partners

  1. In turn, LIMK1 (显示 LIMK1 ELISA试剂盒) and LIMK2 are required for MT1-MMP (显示 MMP14 ELISA试剂盒)-dependent matrix degradation and cell invasion in a three-dimensional type I collagen environment.

  2. High LIMK2 expression is associated with alcoholic hepatitis.

  3. these results suggested that TUG1 mediates cell growth and chemoresistance of SCLC by regulating LIMK2b via EZH2 (显示 EZH2 ELISA试剂盒).

  4. LIMK2 (rs149034313) is associated with Behcet's disease. The LIMK2 association is a missense variant with predicted protein damage that may influence functional interactions with proteins involved in cytoskeletal regulation by Rho GTPase (显示 RACGAP1 ELISA试剂盒), inflammation mediated by chemokine (显示 CCL1 ELISA试剂盒) and cytokine signaling pathways, T cell activation, and angiogenesis.

  5. We observed marked increases in LIM kinase 2 (LIMK2) and cofilin 1 (CFL1 (显示 CFL1 ELISA试剂盒)) gene expressions in metabolic syndrome patients.

  6. This study showed that LIMK2 messenger RNA levels was significantly upregulated in subjects with schizophrenia in laminar and cellular samples.

  7. Actin remodelling factor LIMK2 is a key player in the ciliogenesis control network in which YAP (显示 YAP1 ELISA试剂盒)/TAZ (显示 TAZ ELISA试剂盒) and directional vesicle trafficking are integral components.

  8. Results show that in addition to a potential role in promoting metastasis, changes in LIMK1 (显示 LIMK1 ELISA试剂盒) and LIMK2 expression and/or activity might contribute to AR function in prostate cancer via regulation of microtubule cytoskeletal dynamics.

  9. results highlight the exciting possibility of combining specific LIMK2 inhibitors with anticancer drugs in the treatment of multi-drug resistant cancers

  10. LIMK2 expression was reduced in intestinal tumours of cancer-prone mice and in human colorectal cancer cell lines and tumours. LIMK2 expression progressively decreased with advancing stage of colorectal cancer.

Mouse (Murine) LIM Domain Kinase 2 (LIMK2) interaction partners

  1. These data suggest that osteoblasts can increase their mechanosensitivity under continuous mechanical stimulation by reducing the actin stress fiber formation through inhibiting the LIMK2 expression.

  2. LIMK2 expression was reduced in intestinal tumours of cancer-prone mice.

  3. LIMK2 activity is required for keratinocyte migration in the developing eyelid.

  4. Using RNAi against LIMK2 to inhibit the cytoskeleton reorganization can promote the expression of c-fos gene and thus enhance the mechanosensitivity of c-fos gene in osteoblasts.

  5. Results suggest that constitutive activation of the Rho-ROCK-LIM (显示 PDLIM5 ELISA试剂盒) kinase pathway by extracellular production of lysophosphatidic acid by the action of autotaxin (显示 ENPP2 ELISA试剂盒) is required to maintain the large size of lysosomes in visceral endoderm cells.

  6. LIMK-1 (显示 LIMK1 ELISA试剂盒)/2 double knockout mice were more severely impaired in both ADF/cofilin (显示 CFL1 ELISA试剂盒) phosphorylation and excitatory synaptic function in the CA1 (显示 CA1 ELISA试剂盒) region of the hippocampus.

  7. a novel pathway emanating from the TGF-beta type I receptor (显示 TGFBR1 ELISA试剂盒) and leading to regulation of actin assembly, via the kinase LIMK2.

LIMK2 抗原简介

Antigen Summary

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LIMK2

  • LIM domain kinase 2 L homeolog (limk2.L) 抗体
  • LIM domain kinase 2 (limk2) 抗体
  • LIM domain kinase 2 (LIMK2) 抗体
  • LIM domain kinase 2 (Limk2) 抗体
  • LIM motif-containing protein kinase 2 (Limk2) 抗体
  • 9430059K01 抗体
  • A930024P04Rik 抗体
  • C85310 抗体
  • LIMK 抗体
  • LIMK2 抗体
  • Limk2a 抗体
  • Limk2b 抗体
  • Link2 抗体
  • wu:fa97c09 抗体
  • wu:fk73e11 抗体
  • xlimk2 抗体
  • zgc:91990 抗体

Protein level used designations for LIMK2

XLIM-Kinases2 , LIM domain kinase 2 , LIM domain kinase 2-like , LIM motif-containing protein kinase 2 , LIMK-2 , LIM kinase 2 , LIM-containing protein kinase 2a , LIM-containing protein kinase 2t , Limk2t-1 and Limk2t-2

398298 Xenopus laevis
436924 Danio rerio
486363 Canis lupus familiaris
100058419 Equus caballus
100216249 Xenopus (Silurana) tropicalis
100223808 Taeniopygia guttata
100396965 Callithrix jacchus
100586214 Nomascus leucogenys
458970 Pan troglodytes
716614 Macaca mulatta
100478557 Ailuropoda melanoleuca
3985 Homo sapiens
29524 Rattus norvegicus
513539 Bos taurus
396010 Gallus gallus
16886 Mus musculus
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