anti-Kinesin Family Member 20A (KIF20A) 抗体

Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. 再加上,我们可以发Kinesin Family Member 20A 试剂盒 (5)Kinesin Family Member 20A 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
KIF20A 10112 O95235
KIF20A 19348 P97329
KIF20A 361308  
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产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 IHC, WB KIF20A antibody - middle region (AV) validated by WB using 721_B Cell Lysate at 1ug/ml. KIF20A is supported by BioGPS gene expression data to be expressed in 721_B 100 μL 2至3个工作日
$289.00
详细
非结合性 ELISA, WB Western blot analysis of extracts from 293 cells, using KIF20A (Phospho-Ser528) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2至3个工作日
$302.50
详细
非结合性 IF, IHC, ELISA, WB Western blot analysis of extracts from 293 cells, using KIF20A (Ab-528) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KIF20A (Ab-528) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2至3个工作日
$302.50
详细
Cow 非结合性 IHC, IHC (p), WB Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Spleen, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μL 11至14个工作日
$727.83
详细
非结合性 ELISA, IHC, WB ABIN6269746 at 1/100 staining human brain tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6269746 at 1/100 staining rat heart tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11至12个工作日
$450.00
详细
非结合性 IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti KIF20A/MKLP2 Polyclonal Antibody, Unconjugated (ABIN872316) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3至7个工作日
$317.90
详细
非结合性 ELISA, IF, IHC, WB 100 μL Available
$363.46
详细
非结合性 ELISA, IHC, WB 100 μL Available
$363.46
详细
非结合性 ELISA, ICC, IF, IHC, WB ABIN6278585 staining KIF20A in human brain tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Western blot analysis of KIF20A using LOVO whole cell lysates 100 μL 11至12个工作日
$390.77
详细
非结合性 ELISA, WB Western blot analysis of KIF20A in lysates of 293, using KIF20A Antibody(ABIN6270593). 100 μL 11至12个工作日
$450.00
详细

引用最多的anti-Kinesin Family Member 20A 抗体

  1. Human Polyclonal KIF20A Primary Antibody for WB - ABIN523488 : Lee, McCormick, Saya: Mad2 inhibits the mitotic kinesin MKlp2. in The Journal of cell biology 2010 (PubMed)

更多抗Kinesin Family Member 20A的相互作用对抗体

Zebrafish Kinesin Family Member 20A (KIF20A) interaction partners

  1. Report expression of mt2 and smt-B upon cadmium exposure and cold shock in zebrafish (Danio rerio).

Human Kinesin Family Member 20A (KIF20A) interaction partners

  1. our study demonstrated that KIF20A might confer malignant phenotype to LUAD by regulating cell proliferation and apoptosis, providing a new potential biomarker for clinical treatment of LUAD.

  2. KIF20A promotes the proliferation and metastasis of bladder cancer cells. Bladder cancer patients with a high KIF20A expression have a worse tumour differentiation and a poor prognosis.

  3. High expression of KIF20A is associated with recurrence in pancreatic cancer.

  4. KIF20A-knockdown exhibits a suppressive effect on the cell cycle and has an inhibitory effect on the terminal cell division process (cytokinesis) leading to partial multinuclearity of the cells.

  5. In conclusion, our findings indicated that FOXM1 was highly expressed in lung cancer cells after exposure to ionizing radiation (IR). We also found that FOXM1 promoted radioresistance, invasion, migration, and EMT of lung cancer cells after IR, partly through upregulating KIF20A.

  6. Although the present study was preliminary, these data indicate the possible involvement of KIF20A in the proliferation of clearcell carcinoma (CCC), suggesting that targeting this molecule may contribute to reversing the malignant potential consequently affecting the oncologic outcome of CCC patients.

  7. Results suggest that coupling between actin and microtubule cytoskeletons driven by Myosin II and KIF20A ensures the spatial coordination between RAB6-positive vesicles fission from Golgi/trans-Golgi network membranes and their exit along microtubules.

  8. Study reveals the mechanism controlling abscission through integration of Aurora B kinase and B56-bound PP2A phosphatase activities on the kinesin motor protein MKlp2. MKlp2 is an essential protein for promoting abscission, which may regulate tethering and stabilizing of the PM to the microtubule cytoskeleton at the intercellular bridge through its previously uncharacterized lipid association motif.

  9. Identification of a novel autosomal recessive congenital restrictive cardiomyopathy, caused by a near complete loss-of-function of KIF20A.

  10. While the MKLP2 neck-linker is directed towards the microtubule plus-end in an ATP-like state, it does not fully dock along the motor domain. Furthermore, the footprint of the MKLP2 motor domain on the microtubule surface is altered compared to motile kinesins, and enhanced by kinesin-6-specific sequences.

  11. High KIF20A expression is associated with hepatocellular carcinoma.

  12. Study shows that the kinesin family member 20A (KIF20A) is a tumor-associated antigen involved in the glioma cell growth and cell survival, suggesting that KIF20A is an oncoantigen of gliomas.

  13. Signaling cascade of the NIMA-related kinases (Neks) Nek6, Nek7, and Nek9 is required for the localization and function of two kinesins essential for cytokinesis, Mklp2 and Kif14 to properly coordinate cytokinesis.

  14. KIF20A is overexpressed and may serve as an independent prognostic biomarker in Nasopharyngeal Cancer. Targeting KIF20A reduces migration and invasion of Nasopharyngeal Cancer cells.

  15. elevated KIF20A expression correlates with HPV infection, clinical stage, tumor recurrence, lymphovascular space involvement, pelvic lymph node metastasis, and poor outcome in early-stage cervical squamous cell carcinoma patients.

  16. we identify KIF20A as a direct transcriptional target of FOXM1, involved in paclitaxel action and resistance

  17. Our results provide insight into the link between regulation of KIF20A-mediated trafficking of IGF2BP3-containing stress granules and modulation of the motility and invasiveness in pancreatic cancers.

  18. Kif20a expression was upregulated in pancreatic ductal adenocarcinoma and pancreatic neuroendocrine cancer compared with normal pancreas. Kif20a silencing resulted in inhibition of proliferation, motility, and invasion of pancreatic cancer cell lines.

  19. Authors propose that phosphoregulation of MKlp2 by Cdk1/cyclin B1 ensures that activation of MKlp2 kinesin and relocation of the CPC occur at the appropriate time and space for proper mitotic progression and genomic stability.

  20. targeting Aurora B to the cell cortex (or the equatorial cortex) by MKlp2 is essential for the maintenance of the ingressing furrow for successful cytokinesis

Mouse (Murine) Kinesin Family Member 20A (KIF20A) interaction partners

  1. It has been reported that mitotic kinesin KIF20A interacts with RGS3 and plays a crucial role in controlling the division modes of neural progenitor cells during cortical neurogenesis.

Kinesin Family Member 20A (KIF20A) 抗原简介

蛋白简介

Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.

Gene names and symbols associated with KIF20A

  • kinesin family member 20A (kif20a) 抗体
  • kinesin family member 20A L homeolog (kif20a.L) 抗体
  • kinesin family member 20A (KIF20A) 抗体
  • kinesin-like protein KIF20A (LOC100223319) 抗体
  • kinesin-like protein KIF20A (LOC100231271) 抗体
  • kinesin family member 20A (Kif20a) 抗体
  • AA415432 抗体
  • LOC325449 抗体
  • MGC79056 抗体
  • MGC112061 抗体
  • MKLP2 抗体
  • mt2 抗体
  • Rab6kifl 抗体

Protein level used designations for KIF20A

kinesin family member 20A , metallothionein 2 , kinesin-like protein KIF20A-like , GG10_2 , RAB6 interacting, kinesin-like (rabkinesin6) , kinesin-like protein KIF20A , mitotic kinesin-like protein 2 , rab6-interacting kinesin-like protein , rabkinesin-6 , Rabkinesin-6 , kinesin-like protein 174

GENE ID SPECIES
325449 Danio rerio
446474 Xenopus laevis
462091 Pan troglodytes
496538 Xenopus (Silurana) tropicalis
100062393 Equus caballus
100223319 Taeniopygia guttata
100231271 Taeniopygia guttata
100345407 Oryctolagus cuniculus
100387561 Callithrix jacchus
100482186 Ailuropoda melanoleuca
100515193 Sus scrofa
100586722 Nomascus leucogenys
10112 Homo sapiens
416220 Gallus gallus
474693 Canis lupus familiaris
527854 Bos taurus
19348 Mus musculus
361308 Rattus norvegicus
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