Kinesin Family Member 14 (KIF14) ELISA试剂盒

KIF14 is a member of the kinesin superfamily of microtubule-associated motors (see MIM 148760) that play important roles in intracellular transport and cell division (Nakagawa et al., 1997 [PubMed 9275178]).[supplied by OMIM, Mar 2008].. 再加上,我们可以发KIF14 抗体 (41)KIF14 蛋白 (3)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
KIF14 9928 Q15058
小鼠 KIF14 KIF14 381293  
大鼠 KIF14 KIF14 360849  
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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
0.126 ng/mL 0.31 ng/mL - 20 ng/mL   96 Tests Log in to see 13至16个工作日

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Human Kinesin Family Member 14 (KIF14) interaction partners

  1. KIF14 missense and loss of function variants were identified in intellectual disability with microcephaly patients.

  2. KIF14 is upregulated in PCa cell lines and clinical PCa tissues. Inhibition of KIF14 suppresses cell proliferation, induces G2 arrest and apoptosis.

  3. In particular, counteracting forces between minus-end-directed kinesin-14 and plus-end-directed kinesin-5 motors have recently been implicated in the regulation of microtubule nucleation.

  4. The mechanochemical cycle of kinesin-14 has been reported.

  5. Data indicate that three genes, KIF14, NCAPG and CENPE that were upregulated in Pediatric high-grade gliomas (pHGGs) and were direct miR-137 or miR-6500-3p targets.

  6. This study identified the mutations in KIF14 as a new cause of primary microcephaly and using cellular experiments demonstrate that impaired cytokinesis, increased apoptosis, and reduced cell motility are features of the associated pathogenesis.

  7. Signaling cascade of the NIMA-related kinases (Neks) Nek6, Nek7, and Nek9 is required for the localization and function of two kinesins essential for cytokinesis, Mklp2 and Kif14 to properly coordinate cytokinesis.

  8. Studied overexpression of KIF14 which showed the tight correlation between KIF14 upregulation and inferior clinical outcome in medulloblastoma (MB), suggesting KIF14 is a potential negative prognostic marker in MB. Transient, siRNAs-mediated downregulation of KIF14 suppressed cell proliferation and induced apoptosis in two MB cell lines.

  9. study suggests that KIF14 may serve as a predictor of poor survival and a novel prognostic biomarker of chemoresistance to paclitaxel treatment in cervical cancer.

  10. analysis of epigenetic regulation of KIF14 overexpression in ovarian cancer

  11. Kinesin-14 blocks microtubule nucleation in yeast and reveal that this inhibition is countered by the kinesin-5 protein, Cut7.[Cut7, Pkl1]

  12. High-grade serous ovarian cancer cells may depend on KIF14 for in vitro proliferation.

  13. Mutations in KIF14 identified as a novel cause of an autosomal recessive lethal fetal ciliopathy phenotype.

  14. critical role for KIF14 in the tumorigenic potential of triple-negative breast cancer

  15. High KIF14 expression is associated with hepatocellular carcinoma.

  16. KIF14 knockdown downregulates the expression of Skp2 and Cks1, leading to accumulation of p27Kip1.

  17. KIF14 inhibits tumor growth and cancer metastasis in lung adenocarcinoma.

  18. Data indicate that KIF14 and TLN1 loss-of-function significantly enhanced chemosensitivity in four triple-negative breast cancer (TNBC) cell lines.

  19. Suppression of KIF14 not only decreases cancer cell migration but also induces apoptosis of cells.

  20. KIF14 expression in gliomas is tumor-specific and increased in more aggressive tumors. KIF14 might function as a candidate prognostic marker for human gliomas.

Mouse (Murine) Kinesin Family Member 14 (KIF14) interaction partners

  1. Data provide the first evidence that Kif14 can promote tumor formation in susceptible cells in vivo

  2. The ADP-bound form of the KIF14 motor domain reveals a dramatically opened ATP-binding pocket.

  3. Kif14 mutation causes severe brain malformation and hypomyelination.

KIF14 抗原简介

Antigen Summary

KIF14 is a member of the kinesin superfamily of microtubule-associated motors (see MIM 148760) that play important roles in intracellular transport and cell division (Nakagawa et al., 1997

Gene names and symbols associated with KIF14

  • kinesin family member 14 (KIF14) 抗体
  • kinesin family member 14 (kif14) 抗体
  • kinesin-like protein KIF14 (LOC100641544) 抗体
  • kinesin family member 14 (Kif14) 抗体
  • D1Ertd367e 抗体
  • E130203M01 抗体
  • KIF14 抗体
  • si:dkey-39e8.3 抗体
  • wu:fi16h07 抗体

Protein level used designations for KIF14

kinesin family member 14 , kinesin-like protein KIF14 , kinesin-like protein KIF14-like , N-3 kinesin

424347 Gallus gallus
562052 Danio rerio
709293 Macaca mulatta
100027148 Monodelphis domestica
100145032 Xenopus (Silurana) tropicalis
100358026 Oryctolagus cuniculus
100391549 Callithrix jacchus
100547684 Meleagris gallopavo
100579832 Nomascus leucogenys
100641544 Amphimedon queenslandica
9928 Homo sapiens
381293 Mus musculus
360849 Rattus norvegicus
490248 Canis lupus familiaris
531074 Bos taurus
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