Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4 ELISA试剂盒

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells.

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    试剂盒
抗原
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适用
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3 产品
Pre-coated, 样品类型: Cell Culture Supernatant, Cell Lysate, Tissue Homogenate
适用
检测方法Colorimetric, Sandwich ELISA
检测范围1.56 ng/mL - 100 ng/mL
订购详情 分类号码 ABIN417677
$700.00
加上运输费 $45.00
13至16个工作日
Pre-coated, 样品类型: Cell Culture Supernatant, Cell Lysate, Tissue Homogenate
适用
检测方法Colorimetric, Sandwich ELISA
检测范围0.156 ng/mL - 10 ng/mL
订购详情 分类号码 ABIN1570891
$870.62
加上运输费 $45.00
15至17个工作日
Pre-coated, 样品类型: Cell Culture Supernatant, Cell Lysate, Tissue Homogenate
适用
检测方法Colorimetric, Sandwich ELISA
检测范围1.56 ng/mL - 100 ng/mL
订购详情 分类号码 ABIN5656218
$928.46
96 tests
加上运输费 $45.00
8至12个工作日
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Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4 (KIR2DS4) 抗原简介

蛋白简介

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Gene names and symbols associated with KIR2DS4

  • killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4 (KIR2DS4) 抗体
  • CD158I 抗体
  • KIR1D 抗体
  • KIR412 抗体
  • KKA3 抗体
  • NKAT8 抗体

Protein level used designations for KIR2DS4

CD158 antigen-like family member I , KIR antigen 2DS4 , MHC class I NK cell receptor , NKAT-8 , P58 natural killer cell receptor clones CL-39/CL-17 , killer cell immunoglobulin-like receptor 2DS4 , killer inhibitory receptor 4-1-2 , natural killer cell inhibitory receptor , natural killer-associated transcript 8 , p58 NK receptor CL-39/CL-17

GENE ID SPECIES
3809 Homo sapiens
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