anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2) 抗体

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. 再加上,我们可以发KIR2DL2 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
KIR2DL2 3803 P43627
KIR2DL2    
KIR2DL2    
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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB Western blot analysis of CD158b1 expression in MDAMB231 (A), Jurkat (B), mouse liver (C), H9C2 (D) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
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非结合性 FACS, WB KIR2DL2 Antibody (C-Term) (ABIN651949) western blot analysis in MDA-MB231,Jurkat cell line lysates (35 µg/lane). This demonstrates the KIR2DL2 antibody detected the KIR2DL2 protein (arrow). KIR2DL2 Antibody (C-Term) (ABIN651949) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10至11个工作日
$385.00
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非结合性 ELISA, WB Western blot analysis of KIR2DL2 using NIH-3T3 whole cell lysates 100 μL Log in to see 11至12个工作日
$390.77
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非结合性 ICC, IHC, WB DAB staining on IHC-P; Samples: Human Bile duct cancer Tissue 100 μg Log in to see 13至16个工作日
$350.00
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小鼠 非结合性 FACS, IP   200 μg Log in to see 11至14个工作日
$1,057.83
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非结合性 WB   100 μL Log in to see 11至14个工作日
$390.50
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Biotin WB   100 μL Log in to see 11至14个工作日
$639.83
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FITC WB   100 μL Log in to see 11至14个工作日
$683.83
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非结合性 WB   100 μL Log in to see 11至14个工作日
$375.83
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非结合性 FACS, WB   50 μg Log in to see 11至14个工作日
$383.17
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更多抗KIR2DL2的相互作用对抗体

Human Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2) interaction partners

  1. The results suggest that KIR2DL2 and 2DS4del could have a risk role in the development of Systemic Sclerosis, but not with clinical manifestations.

  2. Killer cell immunoglobulin like receptor two (KIR2DL2) shows a risk association with Chinese Han hepatitis C virus-1b (HCV-1b) patients not responding to the combination therapy of pegylated alpha interferon (PEG-IFN) with ribavirin (RBV).

  3. KIR2DL2/HLA-C( *)12:02 and KIR2DL2/HLA-C( *)14:03 compound genotypes have protective effects on control of HIV-1.

  4. KIR2DL2 gene polymorphism is associated with HIV-1 infection.

  5. association between KIR2DS2 and the response to methotrexate (MTX), moreover, the combination KIR2DL2+/KIR2DS2+ was more frequent in responders to MTX (p = 0.043).

  6. KIR2DL2/KIR2DL3-glutamate(35) alleles are functionally stronger than -glutamine(35) alleles.

  7. KIR2DL2/2DS2-C1C1 genotype is associated with type 1 diabetes in Saudi children

  8. genetic association study in population in Eastern India: Data suggest that interactions between KIRs (KIR2DL2, KIR2DS4, KIR2DL3) and HLA ligands (HLAC1, HLAC2) contribute significantly toward susceptibility and protection toward type 1 diabetes.

  9. Allelic polymorphism of KIR2DL2/2DL3 in a southern Chinese population.

  10. a significant increase in the frequency of KIR2DL2 (P = 0.019) as well as KIR2DS2 (P = 0.008) in patients with neuroblastoma compared with the healthy control group, was found.

  11. Single Nucleotide Polymorphism in KIR2DL2 gene is associated with Asthma and Atopic Dermatitis.

  12. genetic polymorphism is associated with chronic hepatitis C and levels of viremia in Poland

  13. KIR2DL2 and KIR2DS2 genotype is associated with protection against primary biliary cirrhosis in Han population.

  14. Genetic risk for co-occurrence of type 1 diabetes and celiac disease is modified by HLA-C and killer immunoglobulin-like receptors.

  15. Authors showed an increase in HLA-C1/KIR2DL2 and HLA-C1/KIR2DL3 pairs in human papillomavirus high-risk infected patients (OR 3.05, 3.24) with invasive cervical cancer (OR 1.33, 3.68).

  16. KIR2DL3-positive NK cells were more sensitive to changes in the peptide content of MHC class I than KIR2DL2-positive NK cells.

  17. Authors showed a significant increased correlation between KIR2DL2/DS2, type 2 diabetes and HLA-C1C1 genotype in the type 2 diabetes patients infected with human herpesvirus 8.

  18. these results suggest that inhibitory KIR2DL2 and KIR2DL3, which are alleles of the same locus, play a role in the inverse effects on PM and PM/HIV co-infection

  19. These data show that naturally occurring sequence variations within HLA-C03:04-restricted HIV-1 p24 Gag epitopes can have a significant impact on the binding of inhibitory KIR2DL2 receptors and primary natural killer cell function.

  20. The strongest association for the development of epithelial ovarian cancer has been found between KIR2DL2 and HLA-C1 expression.

KIR2DL2 抗原简介

蛋白简介

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Gene names and symbols associated with KIR2DL2

  • killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 (KIR2DL2) 抗体
  • CD158b 抗体
  • CD158B1 抗体
  • NKAT6 抗体
  • p58.2 抗体

Protein level used designations for KIR2DL2

CD158 antigen-like family member B1 , MHC class I NK cell receptor , NKAT-6 , killer cell immunoglobulin-like receptor 2DL2 , natural killer-associated transcript 6 , p58 NK receptor CL-43 , p58 natural killer cell receptor clone CL-43

GENE ID SPECIES
3803 Homo sapiens
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