Keratin 5 蛋白 (KRT5)

The protein encoded by KRT5 is a member of the keratin gene family. 再加上,我们可以发Keratin 5 抗体 (284)Keratin 5 试剂盒 (15)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
KRT5 110308 Q922U2
KRT5 3852 P13647
KRT5 369017 Q6P6Q2
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Showing 9 out of 15 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
大肠杆菌(E. Coli) GST tag 100 μg Log in to see 11 Days
大肠杆菌(E. Coli) His tag,S tag   50 μg Log in to see 13至16个工作日
小麦胚 GST tag 10 μg Log in to see 11至12个工作日
大肠杆菌(E. Coli) 小鼠 非结合性 SDS-PAGE analysis of Mouse Keratin 5 Protein. 100 μg Log in to see 11至18个工作日
酵母菌 Cow His tag   1 mg Log in to see 60至71个工作日
大肠杆菌(E. Coli) 大鼠 His tag,S tag   100 μg Log in to see 15至18个工作日
大肠杆菌(E. Coli) 非结合性   100 μg Log in to see 11至18个工作日

KRT5 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine)

Human ,
, ,
Rat (Rattus)

更多Keratin 5 (KRT5)互动伙伴

Mouse (Murine) Keratin 5 (KRT5) interaction partners

  1. We demonstrate using lineage-tracing systems that urothelial regeneration following augmentation cystoplasty with acellular grafts exclusively depends on host keratin 5 (显示 KRT36 蛋白)-expressing basal cells to repopulate all lineages of the de novo urothelium at implant sites

  2. CDK1 (显示 CDK1 蛋白), Aurora-B (显示 AURKC 蛋白), and Rho-kinase (显示 ROCK2 蛋白) phosphorylate keratin 5 (显示 KRT36 蛋白)/14.

  3. Taken together, our data demonstrated that Krt5-expressing cells could be involved in the natural pancreas self-healing process and the renewal of beta cells after AP in adult mice. It is promising that promoting conversion of Krt5-expressing cells into functional beta cells may be a novel method to mitigate the development of diabetes mellitus after AP in vivo.

  4. RA regulates Krt5 and Krt14 (显示 KRT14 蛋白) expression independently of stem cell character in developing salivary epithelium. The stem cell gene Kit is regulated inversely from Krt5/Krt14 (显示 KRT14 蛋白) by RA signaling.

  5. widespread destruction of airway and alveolar epithelial cells following severe influenza infection triggers a wound-healing response that initiates in the airways with the proliferation of rare airway-resident SOX2 (显示 SOX2 蛋白)+ Lin- progenitor cells. These cells then give rise to nascent KRT5+ cells in remodeled airways and populate the damaged alveolar parenchyma.

  6. Loss of activating transcription factor 3 (ATF3 (显示 ATF3 蛋白)) in knockout mice promotes the emergence of keratins CK5+CK8 (显示 KRT8 蛋白)+ epithelial cells.

  7. Directed expression of a chimeric type II keratin (显示 KRT80 蛋白) partially rescues keratin 5 (显示 KRT36 蛋白)-null mice.

  8. NMHC IIA may play critical roles in the early trophoblast-derived ectoplacental cone and extraembryonic ectoderm in Keratin 5 (显示 KRT36 蛋白)-Cre transgenic mice.

  9. Mice lacking the prostate epithelial AR have increased apoptosis in epithelial CK8 (显示 KRT8 蛋白)-positive luminal cells and increased proliferation in epithelial CK5-positive basal cells.

  10. The involvement of Hsc70 and Hsp70 in mutant keratin degradation was demonstrated using CHIP-p.Met1_Ala142del (DeltaTPR-CHIP).

Human Keratin 5 (KRT5) interaction partners

  1. Cytokeratin 5/6 and CK8 (显示 KRT8 蛋白)/18 immunohistochemistry on 150 cases of triple negative breast cancers was performed and association with various clinicopathological features was evaluated.

  2. Data indicate that cytokeratin 5/6 (CK5/6) is an independent prognostic biomarker in urothelial carcinoma and therefore can be used in the prognostic stratification of the patients with bladder cancer.

  3. CK5/6 expression changed according to the morphological components in adenoid cystic carcinoma of the breast.

  4. EGFR (显示 EGFR 蛋白) and CK5/6 expression could serve as biomarkers for identifying triple-negative breast cancer patients with poor survival

  5. Basal cell carcinoma (BCC) typically shows patchy CD56 (显示 NCAM1 蛋白) expression and diffuse CK5/6 positivity. These 2 markers can be used to distinguish between BCC and Merkel cell carcinoma in challenging cases.

  6. Negative staining for CK5/6 and p63 (显示 RPE65 蛋白) can be helpful to distinguish Well-differentiated neuroendocrine tumors (WDNETs) from cutaneous adnexal neoplasms. It is important to consider WDNETs in the differential diagnosis of cutaneous adnexal neoplasms as low-grade tumors may be the first sign of aggressive metastatic disease

  7. this study adds a further 10 novel mutations to the catalogued genotype-phenotype correlations in epidermolysis bullosa simplex and demonstrates a potential modifying effect of SNPs on the phenotype. We therefore support the notion of full DNA sequencing of both KRT5 and KRT14 (显示 KRT14 蛋白) genes so as to not miss any variants in the genes contributing to the phenotype.

  8. Flat Intraurothelial Neoplasia Exhibiting Diffuse Immunoreactivity for CD44 (显示 CD44 蛋白) and Cytokeratin 5 (Urothelial Stem Cell/Basal Cell Markers): A Variant of Intraurothelial Neoplasia Commonly Associated With Muscle-invasive Urothelial Carcinoma

  9. Dual small interfering RNA (siRNA) silencing of RARalpha (显示 RARA 蛋白) and RARgamma reversed RA blockade of P4-induced CK5. Using promoter deletion analysis, we identified a region 1.1 kb upstream of the CK5 transcriptional start site that is necessary for P4 activation and contains a putative progesterone response element (PRE

  10. Cytokeratin 5/6 protein expression as a frequent feature of high-grade serous ovarian carcinoma with various staining patterns. Cytokeratin 5/6 in combination with ER-alpha (显示 ESR1 蛋白) proved to be a negative prognostic marker.

Cow (Bovine) Keratin 5 (KRT5) interaction partners

  1. NMHC IIA may play critical roles in the early trophoblast-derived ectoplacental cone and extraembryonic ectoderm in Keratin 5-Cre transgenic mice.

Zebrafish Keratin 5 (KRT5) interaction partners

  1. data show that a cis (显示 CISH 蛋白)-element of the DNA segment in the CKII gene is required for epidermal cell-specific expression of CKII and that a minimal region upstream of the transcription start site is required for this expression restricted to epidermal cells

蛋白简介Keratin 5 (KRT5)


The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene names and symbols associated with Keratin 5 蛋白 (KRT5)

  • keratin 5 (Krt5)
  • keratin 5 (KRT5)
  • keratin 5 (krt5)
  • 3300001P10Rik 蛋白
  • AW146334 蛋白
  • CK-5 蛋白
  • CK5 蛋白
  • ckii 蛋白
  • DDD 蛋白
  • DDD1 蛋白
  • EBS2 蛋白
  • K5 蛋白
  • Keratin-5 蛋白
  • Krt2-5 蛋白
  • KRT5A 蛋白
  • KRT75 蛋白
  • Sak57 蛋白
  • Tfip8 蛋白
  • wu:fb02h09 蛋白
  • wu:fj02d02 蛋白
  • wu:fk78b12 蛋白
  • zfCKII 蛋白

Protein level used designations for Keratin 5 蛋白 (KRT5)

58 kDa cytokeratin , CK-5 , cytokeratin 5 , cytokeratin-5 , keratin complex 2, basic, gene 5 , keratin, type II cytoskeletal 5 , keratin-5 , tuftelin interacting protein 8 , type-II keratin Kb5 , 58 kda cytokeratin , epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types , keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types) , K5 , keratin, type II cytoskeletal 60 kDa, component III , keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types) , type II cytokeratin , keratin 75 , type II alpha keratin IIA , Cytokeratin-5 , Type-II keratin Kb5

110308 Mus musculus
3852 Homo sapiens
281268 Bos taurus
369017 Rattus norvegicus
797351 Danio rerio
407779 Gallus gallus
100615215 Pan troglodytes
100687760 Canis lupus familiaris
100511564 Sus scrofa
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