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The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. 再加上，我们可以发Jun D Proto-Oncogene 抗体 (160) 和 Jun D Proto-Oncogene 蛋白 (8)和数多这个蛋白质的别的产品。
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identify AP-1(JunD/c-Fos) as a novel hematopoietic transcription factor and the requirement of AP-1(JunD/c-Fos) in BMP-4 (显示 BMP4 ELISA试剂盒)-induced hematopoiesis during Xenopus hematopoiesis.
Data indicate the mechanism underlying redox-regulation of AP-1 Fos/Jun transcription factors and suggest structural insight for therapeutic interventions targeting AP-1 proteins.
In T cells, after serum deprivation HBZ (显示 HBZ ELISA试剂盒) induces the expression of Delta JunD isoform. Unlike JunD, Delta JunD induces proliferation and transformation of cells. HBZ (显示 HBZ ELISA试剂盒) bypasses translational control of JunD uORF and favors the expression of Delta JunD. The truncated isoform Delta JunD has a central role in the oncogenic process leading to adult T-cell leukemia .
MiR (显示 MLXIP ELISA试剂盒)-663a suppresses proliferation and invasion by targeting AP-1 (显示 FOSB ELISA试剂盒) component JunD in non-small cell lung cancer cells.
studies showed that down-regulation of JunD in response to TGF-beta (显示 TGFB1 ELISA试剂盒) treatment is mediated via the proteasomal degradation pathway.
CARMA1 (显示 CARD11 ELISA试剂盒)- and MyD88 (显示 MYD88 ELISA试剂盒)-dependent activation of Jun (显示 JUN ELISA试剂盒)/ATF-type AP-1 (显示 FOSB ELISA试剂盒) complexes is a hallmark of ABC (显示 ABCB6 ELISA试剂盒) diffuse large B-cell lymphomas.
recombinant SERPINE2 (显示 SERPINE2 ELISA试剂盒) induced a clear inhibition of MMP-13 (显示 MMP13 ELISA试剂盒) expression in IL-1alpha-stimulated chondrocytes. This inhibitory effect is likely regulated through a pathway involving ERK 1 (显示 MAPK3 ELISA试剂盒)/2, NF-kappaB (显示 NFKB1 ELISA试剂盒) and AP-1 (显示 FOSB ELISA试剂盒)
miR (显示 MLXIP ELISA试剂盒)-494 is a novel regulator of HNPC apoptosis induced by TNF-alpha (显示 TNF ELISA试剂盒)
JunD activates miR (显示 MLXIP ELISA试剂盒)-29b by enhancing its transcription and processing, which contribute to the inhibitory effect of JunD
Binding of specific AP-1 (显示 FOSB ELISA试剂盒) factors, we found JunD associated with the LILRB1 (显示 LILRB1 ELISA试剂盒) distal promoter.
Cells in contact with basement membrane undergo transient oscillations between two molecular states defined by their TGFBR3 (显示 TGFBR3 ELISA试剂盒)- JUND expression.
The present data indicate that bovine dialyzable leukocyte extract can block the AP-1 (显示 JUN ELISA试剂盒) DNA-binding activity and expression of several transcriptions factors in breast cancer cells.
Differentiation-mediated activation of JunD results in enhanced TUBB4a expression in P19 embryonal carcinoma cells.
JunD provides protection in aging-induced endothelial dysfunction and may represent a novel target to prevent reactive oxygen species-driven vascular aging.
AP-1 (显示 JUN ELISA试剂盒) composed with JunD and Fra2 (显示 FOSL2 ELISA试剂盒) protein plays a primary role in enhancing the transcription level of the CD11c (显示 ITGAX ELISA试剂盒) gene in dendritic cells
Nfe2 (显示 NFE2 ELISA试剂盒) modulates JunD binding to the Gcm1 (显示 GCM1 ELISA试剂盒) promoter via acetylation
5-HT2B (显示 HTR2B ELISA试剂盒) blockade enhances liver regeneration by inhibiting induction of TGF-beta1 (显示 TGFB1 ELISA试剂盒) expression by hepatic stellate cells that is dependent on 5-HT (显示 DDC ELISA试剂盒), ERK (显示 EPHB2 ELISA试剂盒) and JunD.
CDK4 (显示 CDK4 ELISA试剂盒)-mediated regulation of cell functions via c-Jun (显示 JUN ELISA试剂盒) phosphorylation and AP-1 (显示 JUN ELISA试剂盒) activation
Downregulation of JunD and cyclin D1 (显示 CCND1 ELISA试剂盒) expression in myofibroblasts may be important regarding the mechanism of action of MTA (显示 DNMT1 ELISA试剂盒) in Mdr2 (显示 ABCB4 ELISA试剂盒)-/- mice
c-Jun (显示 JUN ELISA试剂盒), JunB (显示 JUNB ELISA试剂盒), and JunD are not functionally equivalent and have both overlapping and independent functions in controlling cellular proliferation, cell-cycle arrest/senescence and the response to stress.
Study supports potential roles for jun (显示 JUN ELISA试剂盒) D, jun (显示 JUN ELISA试剂盒) B, and fra-1 (显示 FOSL1 ELISA试剂盒) in the dietary energy restriction regulation of AP-1 (显示 JUN ELISA试剂盒) function in the Sencar mouse skin carcinogenesis model.
protects cells from p53 (显示 TP53 ELISA试剂盒)-dependent senescence and apoptosis
The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage, including non-AUG codons, results in the production of different isoforms.
transcription factor jun-D
, JunD-FL isoform
, activator protein 1
, Jun proto-oncogene related gene d1