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JAZF1 encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. 再加上，我们可以发JAZF Zinc Finger 1 抗体 (26) 和 JAZF Zinc Finger 1 蛋白 (5)和数多这个蛋白质的别的产品。
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PNPLA3 (显示 PNPLA3 ELISA试剂盒) and JAZF1 were associated with non-hepatitis B virus and non-hepatitis C virus-related hepatocellular carcinoma development among Japanese patients with type 2 diabetes mellitus
study found SNP rs7754840 in CDKAL1 (显示 CDKAL1 ELISA试剂盒), rs864745 in JAZF1, and rs35767 in IGF1 (显示 IGF1 ELISA试剂盒) might serve as potential susceptibility loci for type 2 diabetes in the Uyghur population
genetic association study in Han population in China: Data suggest an SNP in PXK (显示 PXK ELISA试剂盒) [rs2176082(C/T); but not rs6445975(G/T)] is associated with recurrent pregnancy loss; SNPs in KIAA0319L [rs2275247(A/G)] or JAZF1 [rs1635852(C/T)] are not associated.
In African American men, the association between JAZF1 rs10486567 and prostate cancer may be modified by exposure to heavy metals such as Pb.
study determined that the previously described systemic lupus erythematosus susceptibility loci PXK (显示 PXK ELISA试剂盒) (P = 3.27 x 10(-11), OR = 1.20) and JAZF1 (P = 1.11 x 10(-8), OR = 1.13) are shared with systemic sclerosis
Morphological features, immunoprofile and fluorescence in situ hybridization rearrangements of JAZF1 and PHF1 (显示 PHF1 ELISA试剂盒) genes were correlated with tumor category and outcome in endometrial sarcomas
genetic association studies in a population in Utah: Data suggest that an SNP in JAZF1 (rs1635852) is associated with type 2 diabetes; this SNP in JAZF1 intron 1 is part of a cis-regulatory complex.
This study indicates a nominal role for JAZF1 and BCL11A (显示 BCL11A ELISA试剂盒) variants in type 2 diabetes susceptibility in African-Americans.
Single-nucleotide polymorphism of rs10486567 in JAZF1 is associated with prostate cancer.
The JAZF1 SNPs rs6968704 and rs10486567 were associated with decreased risk of prostate cancer but were not associated with diabetes.
TIP27 has an important role in glucose homeostasis through the regulation of hepatic glucose metabolism and insulin (显示 INS ELISA试剂盒) sensitivity. Furthermore, this regulation requires activation of PI3-kinase (显示 PIK3CA ELISA试剂盒).
aberrant JAZF1 expression contributes to the oncogenesis and type 2 diabetes pathogenesis
JAZF1 overexpression decreased serum cholesterol levels and hepatic cholesterol synthesis by inhibiting CREB (显示 CREB1 ELISA试剂盒)-dependent HMGCR (显示 HMGCR ELISA试剂盒) promoter transcriptional activity.
JAZF1 plays an important role in lipid metabolism and may thus provide a potential tool for the treatment of obesity and lipid metabolism disorders among other diseases
JAZF1 was significantly upregulated during the differentiation of 3T3-L1 preadipocytes. The overexpression of JAZF1 inhibited lipid accumulation in differentiated mature 3T3-L1 adipocytes.
results suggest that Jazf1 plays a critical role in the regulation of lipid homeostasis. Finally, Jazf1 may provide a new therapeutic target in the management of obesity and diabetes
Jazf1 overexpression may induce heart failure symptoms through the upregulation of pro-apoptotic genes in cardiomyocytes.
These results showed that JAZF1 in adipocytes and liver cells reduces lipid synthesis and increases lipolysis
This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized
JAZF zinc finger 1
, juxtaposed with another zinc finger gene 1
, juxtaposed with another zinc finger protein 1
, TAK1-interacting protein 27
, zinc finger protein 802