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The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. 再加上，我们可以发IL27 抗体 (165) 和 IL27 蛋白 (23)和数多这个蛋白质的别的产品。
Showing 10 out of 53 products:
Mouse (Murine) IL27 ELISA Kit for Sandwich ELISA - ABIN365240
Le Texier, Thebault, Carvalho-Gaspar, Vignard, Merieau, Usal, Cuturi, Wood, Chiffoleau: Immunoregulatory function of IL-27 and TGF-?1 in cardiac allograft transplantation. in Transplantation 2012
Human IL27 ELISA Kit for Sandwich ELISA - ABIN414441
Li, Zhang, Ge, Zhou, Qi, Ma, Xue, Zhou, Yang: Elevated interleukin-27 enhances the polarization of Th1/Tc1 cells and the production of proinflammatory cytokines in primary immune thrombocytopenia. in Human immunology 2012
Rat (Rattus) IL27 ELISA Kit for Sandwich ELISA - ABIN416127
Gao, Pang, Zhang, Li, Tu, Zhang, Niu, Xiong, Xiao, Zhao, Gao, Wang: Poria Attenuates Idiosyncratic Liver Injury Induced by Polygoni Multiflori Radix Praeparata. in Frontiers in pharmacology 2016
serum interleukin-27 and interleukin-35 concentrations in patients with Guillain-Barre syndrome
Expression of IL-27 in the serum was markedly increased in patients with sepsis-induced myo (显示 IRF6 ELISA试剂盒)cardial dysfunction compared with that in controls.
IL-27 significantly inhibited the M2 macrophages polarization and dampened the proliferation, migration and metastasis of pancreatic cancer cells and as well enhanced the efficacy of gemcitabine.
IL-27 increased NLRP3 (显示 NLRP3 ELISA试剂盒) inflammasome activation in monocytes with enhanced release of IL-1 beta (显示 IL1B ELISA试剂盒).
this study shows that interleukin 27 is up-regulated in patients with active inflammatory bowel disease
IL-27 polymorphisms might play a protective role for the development of ulcerative colitis in the Mexican population
IL-27 stimulation activated STAT1 (显示 STAT1 ELISA试剂盒) and STAT3 (显示 STAT3 ELISA试剂盒) in HeLa and T98G cells, suggesting that IL-27 engages the STAT1 (显示 STAT1 ELISA试剂盒)/3 pathway, which then leads to the upregulation of IL-6 (显示 IL6 ELISA试剂盒), IP-10 (显示 CXCL10 ELISA试剂盒), and MIG (显示 CXCL9 ELISA试剂盒)
IL-27 and IL-37 limit the induction of particular T cell subsets along with cytokine responses in S. stercoralis infections, which suggest the importance of IL-27 and IL-37 in immune modulation in a chronic helminth infection.
IL-27 is a pivotal regulator in endometriotic immune tolerance by triggering Th17 cells to produce IL-10 (显示 IL10 ELISA试剂盒).
HIV and Tat (显示 TAT ELISA试剂盒) inhibit LPS (显示 IRF6 ELISA试剂盒)-induced IL-27 production in human macrophages via distinct mechanisms: Tat (显示 TAT ELISA试剂盒) through the inhibition of cIAP-1 (显示 BIRC2 ELISA试剂盒)-TRAF-6 (显示 TRAF6 ELISA试剂盒) and subsequent inhibition of PI3K (显示 PIK3CA ELISA试剂盒) and p38 (显示 CRK ELISA试剂盒) MAPKs, whereas HIV through the inhibition of p38 MAPK (显示 MAPK14 ELISA试剂盒) activation.
these data infer that endopeptidase mediated gliadin degradation by macrophages and concomitant IL-27 production drive differentiation of splenic gliadin-specific Tr1-like cells in celiac disease
endogenous levels of IL-27 affected the oncogenic properties of mutant p53 (显示 TP53 ELISA试剂盒) in vivo in a Li-Fraumeni mouse model. Lack of IL-27 signaling led to shortened survival times and increased incidence of osteosarcomas.
Interleukin-27 is upregulated centrally and peripherally after intracerebral hemorrhage. Interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin (显示 LTF ELISA试剂盒).
Serum IL-27 levels and cardiac IL-27 mRNA expression were significantly increased after LPS (显示 TLR4 ELISA试剂盒) injection compared with control specimens.
these findings highlight critical roles for IFN-gamma (显示 IFNG ELISA试剂盒) and IL-27 in the mechanism of respiratory syncytial virus-induced exacerbation
IL-27-induced Sca-1 (显示 Ly6a ELISA试剂盒)(+) T cells had increased expression of effector/memory-associated transcription factor T-bet, Eomes (显示 EOMES ELISA试剂盒) and Blimp1 (显示 PRDM1 ELISA试剂盒).
found that during respiratory virus infection the prototypic inflammatory cytokine IL-6 (显示 IL6 ELISA试剂盒) is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27
We demonstrate that IL-27-deficiency is linked to increased mucosal presence of ILC2 in a model of inflammatory lung disease. Moreover, IL-27-treatment inhibited ILC2 proliferation and cytokine production and significantly reduced their accumulation in vivo.
These data suggest a novel role of the sympathetic neuroendocrine system for the modulation of IL-27-dependent acute inflammation.
results identified a novel mechanism of action of IL-27 on Tregs in the context of cancers.
The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
, IL-27 p28 subunit
, IL-27 subunit alpha
, interleukin 30
, interleukin-27 subunit alpha
, interluekin 27
, interleukin 27 p28 subunit