Interferon, alpha-Inducible Protein 6 蛋白 (IFI6)

IFI6 was first identified as one of the many genes induced by interferon. 再加上,我们可以发IFI6 抗体 (46)IFI6 试剂盒 (7)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
IFI6 2537 P09912
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Showing 3 out of 3 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50至55个工作日
小麦胚 GST tag 10 μg Log in to see 11至12个工作日
酵母菌 His tag   50 μg Log in to see 8至11个工作日

IFI6 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,

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Human Interferon, alpha-Inducible Protein 6 (IFI6) interaction partners

  1. In insulitic islets from living patients with recent-onset T1D, most of the overexpressed ISGs, including GBP1 (显示 GBP1 蛋白), TLR3 (显示 TLR3 蛋白), OAS1 (显示 OAS1 蛋白), EIF2AK2 (显示 EIF2AK2 蛋白), HLA-E (显示 HLAE 蛋白), IFI6, and STAT1 (显示 STAT1 蛋白), showed higher expression in the islet core compared with the peri (显示 PLIN1 蛋白)-islet area containing the surrounding immune cells

  2. In conclusion, over-expression of IFI6 promotes hepatitis C virus RNA replication and rescues the interferon alpha (显示 IFNA 蛋白)-mediated anti-hepatitis C virus activity.

  3. IFI6 inhibits HCV entry by impairing EGFR (显示 EGFR 蛋白) mediated CD81 (显示 CD81 蛋白)/CLDN1 (显示 CLDN1 蛋白) interactions. This may be relevant to other virus entry processes employing EGFR (显示 EGFR 蛋白).

  4. Here we elucidate G1P3, a survival protein induced by interferons (IFNs), as a target of estrogen signaling and a contributor to poor outcomes in estrogen receptor (显示 ESR1 蛋白)-positive (ER(+)) breast cancer.

  5. PRINS regulates G1P3, a gene with anti-apoptotic effects in keratinocytes. siRNA-mediated inhibition of PRINS gene resulted in altered cell morphology and gene expression alterations.

  6. G1P3 protein may have function as a cell survival protein by inhibiting mitochondrial-mediated apoptosis

  7. Respiratory syncytial virus upregulated the mRNA expression of chemokines CC and CXC and interfered with type alpha/beta interferon (显示 IFNA 蛋白)-inducible gene expression by upregulation of MG11 (显示 SAMHD1 蛋白) and downregulation of G1P3.

  8. IFN-alpha2b (显示 ADRA2B 蛋白) induced the expression of G1P3 and antagonized the TRAIL induced apoptosis in myeloma suggesting that either the deregulated or the induced expression of G1P3 could lead to apoptosis resistance in tumor cells.



This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.

Gene names and symbols associated with IFI6

  • interferon, alpha-inducible protein 6 (IFI6)
  • interferon alpha inducible protein 6 (IFI6)
  • 6-16 蛋白
  • FAM14C 蛋白
  • G1P3 蛋白
  • Ifi-6-16 蛋白
  • IFI616 蛋白

Protein level used designations for IFI6

interferon alpha-inducible protein 6 , interferon, alpha-inducible protein clone IFI-6-16 , interferon-induced protein 6-16 , ifi-6-16

100190421 Taeniopygia guttata
2537 Homo sapiens
512913 Bos taurus
450178 Pan troglodytes
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