Inositol-Tetrakisphosphate 1-Kinase (ITPK1) ELISA试剂盒

Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. 再加上,我们可以发ITPK1 抗体 (83)ITPK1 蛋白 (11)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
ITPK1 3705 Q13572
ITPK1 217837 Q8BYN3
大鼠 ITPK1 ITPK1 500709  
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适于 ITPK1 相互作用对的更多 ELISA 试剂盒

Human Inositol-Tetrakisphosphate 1-Kinase (ITPK1) interaction partners

  1. The results suggested that the maternal rs3783903 of ITPK1 might be associated with spina bifida, and the allele G of rs3783903 might affect the binding of AP-1 (显示 FOSB ELISA试剂盒) and the decrease of maternal plasma inositol hexakisphosphate concentration.

  2. Activation of PLC (显示 HSPG2 ELISA试剂盒) by an endogenous cytokine (GBP (显示 HADHA ELISA试剂盒)) in Drosophila S3 cells and its application as a model for studying inositol phosphate signalling through ITPK1.

  3. HEK293 cells stably expressing acetylated ITPK1 had reduced levels of the higher phosphorylated forms of inositol, compared with the levels seen in cells expressing unacetylated ITPK1

  4. 5/6-kinase modifies TNFalpha (显示 TNF ELISA试剂盒)-induced apoptosis by interfering with the activation of TNF-R1 (显示 TNFRSF1A ELISA试剂盒)-associated death domain

  5. analysis of inositol phosphate signaling pathway integration via human ITPK1

Mouse (Murine) Inositol-Tetrakisphosphate 1-Kinase (ITPK1) interaction partners

  1. Data suggest that relative deficiency of one or more inositol phosphates accounts for neural tube defects in inositol 1,3,4-trisphosphate 5/6-kinase knockout mice.

  2. Apical localization of Itpk1 enhances its ability to be a modifier gene product in a murine tracheal cell model of cystic fibrosis (显示 S100A8 ELISA试剂盒).

ITPK1 抗原简介

Antigen Summary

Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain (By similarity). Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway.

Gene names and symbols associated with ITPK1

  • inositol-tetrakisphosphate 1-kinase (ITPK1) 抗体
  • inositol 1,3,4-triphosphate 5/6 kinase (Itpk1) 抗体
  • inositol-tetrakisphosphate 1-kinase L homeolog (itpk1.L) 抗体
  • inositol-tetrakisphosphate 1-kinase a (itpk1a) 抗体
  • inositol-tetrakisphosphate 1-kinase (Itpk1) 抗体
  • BC031182 抗体
  • ITRPK1 抗体
  • wu:fj15d08 抗体
  • zgc:56075 抗体

Protein level used designations for ITPK1

inositol 1,3,4-triphosphate 5/6 kinase , inositol 1,3,4-trisphosphate 5/6 kinase , inositol 1,3,4-trisphosphate 5/6-kinase , inositol-triphosphate 5/6-kinase , ins(1,3,4)P(3) 5/6-kinase , inositol-tetrakisphosphate 1-kinase

GENE ID SPECIES
3705 Homo sapiens
217837 Mus musculus
379828 Xenopus laevis
406290 Danio rerio
423421 Gallus gallus
500709 Rattus norvegicus
518488 Bos taurus
100152339 Sus scrofa
100717610 Cavia porcellus
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