anti-IgA 抗体

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). 再加上,我们可以发IgA 试剂盒 (60)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
973 P11912
小鼠  238447  
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Showing 3 out of 4 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 ELISA, IHC, WB 100 μL 11至13个工作日
非结合性 WB PIGA antibody used at 1 ug/ml to detect target protein. 50 μg 9至11个工作日
猕猴 非结合性 ICC, IHC, WB   100 μL 15至18个工作日


Human IgA interaction partners

  1. Aberrant CD79a and/or PAX5 expression can be found in Acute Myelogenous Leukemia cases with RUNX1 mutations even without the translocation t(8; 21).

  2. The incidence of MYD88 and CD79B mutations in patients with CD5(+) DLBCL is lower than that in patients with DLBCL-SS, suggesting that CD5(+) DLBCL is not the same disease as DLBCL-SS in terms of gene mutation status.

  3. Data show that Bruton tyrosine kinase (BTK)inhibitor Ibrutinib augments MALT lymphoma associated translocation protein (MALT1) inhibition by S-Mepazine in CD79 antigen mutant activated B cell-subtype (ABC) of diffuse large B cell lymphoma (DLBCL).

  4. Phosphorylation of CD79a causes a decrease in helical propensity in the C-terminal region, for CD79b, the opposite was observed and phosphorylation resulted in an increase of helical propensity in the C-terminal part.

  5. High intensity of caries is associated with increased levels of some salivary components - sIgA, histatin-5 and lactoperoxidase.

  6. CD79a plays a functional role in the tumor promoting effects of myeloid cells, and may represent a novel target for cancer therapy.

  7. STN produced significant antitumor effects in a mouse xenograft model of CD79A/B-mutated DLBCL.

  8. CD79a may be helpful marker in the differential diagnosis of classical Hodgkin's lymphoma and primary mediastinal B-cell lymphoma

  9. Unlike the B29 octamer motif, the mb-1 octamer motif does not have the essential sequence required for OBF-1/Bob1 interaction, therefore its promoter is not transactivated by OBF-1/Bob1.

  10. B cell-restricted mb-1 gene: expression, function, and lineage infidelity. Review.

  11. There is a somatic hypermutation of this gene in B-cell lymphoma and multiple myeloma.

  12. Results indicate that PAX5 is a more specific marker than CD79a for B-cell ALL diagnosis.

  13. lower levels of B-cell receptor surface expression observed in chronic lymphocytic leukemia are accounted for by an impaired glycosylation and folding of the mu and CD79a chains.

  14. FISH findings indicate that CD79a, despite its specificity for B-cell differentiation, represented the aberrant presence of a B-cell antigen in leukemias of distinct myeloid linage.

  15. Acute leukemia with t(8;21) coexpresses CytCD79a represent biphenotypic acute leukemia.

  16. Anti-CD79b antibodies downregulated surface B-cell receptor and were trafficked to the lysosomal-like major histocompatibility complex class II-positive compartment of a mouse xenograft model of non-Hodgkin lymphoma.

  17. Ig-alpha was phosphorylated in all myeloma IgG BCR isolates, the 31-kD variant being phosphorylated most frequently. It was not phosphorylated in normal control B cells.

  18. Median survival time of cytoplasmic CD79 alpha positive group was shorter than that of cytCD79a negative group in acute myeloid leukemia.

  19. we determined the significance of loss or downregulation of CD79a, overexpression of cyclinD1, and c-maf expression in bone marrow specimens with plasma cell myeloma

Mouse (Murine) IgA interaction partners

  1. In transgenic mice, IgAN pathogenesis involves impaired clearance of abnormal IgA via CD89, primarily by the Kupffer cells. Conditional IgAN progression in CD89 transgenic mice thus reveals important aspects of IgAN pathogenesis.

  2. Increased production of IL-5 from Peyer's patch cells and the restored Th1-type immune response might cause the production of abnormal IgA and might induce the glomerular deposition of IgA in IGA nephropathy.

  3. pIgR/SIgA deficiency in the airways leads to persistent activation of innate immune responses to resident lung microbiota, driving progressive small airway remodelling and emphysema.

  4. The differential and synergistic effect of retinoic acid and TGF-beta on switching of different B cell subpopulations to IgA, is reported.

  5. Our data suggest a critical role of O-linked glycans attached to the hinge region in the development of IgA nephropathy-like disease induced by 6-19 IgA rheumatoid factor in mice.

  6. Data indicate the importance of the mucosal IgA response in defense against HIV/AIDS.

  7. Glycosylation of the CH2/CH3 interface inhibits interaction with the pathogen IgA binding protein SSL7, while maintaining binding of pIgR, essential to the biosynthesis and transport of SIgA.

  8. Caloric restriction reduces IgA levels and modifies cytokine mRNA expression in mouse small intestine

  9. Aberrant glycosylation of immunoglobulin A causes IGA nephropathy. (review)

  10. CD37 protects against glomerular IgA deposition and renal pathology

  11. IgA of the Igh-2(a) allotype was found to be unique in its total lack of a covalent bond between alpha and L: -chains, formation of which apparently depends on the presence of an "extra" Cys in the hinges of all of the other five allotypes.

  12. Mouse IgA allotypes have major differences in their hinge regions.

  13. secretions of IgAs rather than innate defense peptides are critical to regulation of commensal bacterial flora and that the segmented filamentous bacteria antigens are strong stimuli of the mucosal immune system

  14. ligation of CD40 on B cells, without the addition of other B cell activators or cytokines, results in germline transcription and switch recombination that are largely restricted to the gamma2a gene.

  15. These results suggest that activin A induces IgA isotype switching via Smad3/4-mediated germ line alpha transcription.

  16. Results suggest that mesenteric lymph nodes may play a complementary role in secretory IgA production in aged animals.

  17. tetraspanin protein CD37 inhibits IgA responses and regulates the anti-fungal immune response.

  18. The variable regions associated with IgA of peritoneal B1b cells displayed extensive variation due to somatic hypermutation.

IgA 抗原简介


The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with anti-IgA 抗体

  • CD79a molecule (CD79A) 抗体
  • immunoglobulin heavy constant alpha (Igha) 抗体
  • IG-alpha 抗体
  • IgA 抗体
  • Igh-2 抗体
  • MB-1 抗体

Protein level used designations for anti-IgA 抗体

B-cell antigen receptor complex-associated protein alpha chain , CD79A antigen (immunoglobulin-associated alpha) , MB-1 membrane glycoprotein , ig-alpha , membrane-bound immunoglobulin-associated protein , surface IgM-associated protein , B-cell antigen receptor complex-associated protein alpha-chain , CD79a antigen (immunoglobulin-associated alpha)

281674 Bos taurus
484483 Canis lupus familiaris
973 Homo sapiens
238447 Mus musculus
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