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IKZF3 抗体

(IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012].
IKZF3 抗体 IKZF3 抗体 IKZF3 抗体 (ABIN7267842)

IKZF3 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

IKZF3 抗体  (AA 1-509) IKZF3 抗体  (AA 1-509) IKZF3 抗体 (AA 1-509) (ABIN564938)

IKZF3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3H5-G7 unconjugated

IKZF3 抗体  (AA 1-509) IKZF3 抗体  (AA 1-509) IKZF3 抗体 (AA 1-509) (ABIN524769)

IKZF3 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

IKZF3 抗体 by 适用

Find IKZF3 抗体 for a variety of species such as anti-Human IKZF3, anti-Mouse IKZF3, anti-Cow IKZF3. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find IKZF3 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find IKZF3 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

IKZF3 抗体 by 克隆形成能力

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Find IKZF3 抗体 with a specific conjugate such as PE, Biotin, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular IKZF3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN7267842
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (2)
Cat. No. ABIN564938
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN524769
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN5580710
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7236301
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6258240
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6749714
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN6142290
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Mouse, Pig, Rabbit, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN2780886
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7176569
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IF
Validations
  • (1)
Cat. No. ABIN7263283
Quantity 200 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6737865
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (2)
Cat. No. ABIN651843
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
Cat. No. ABIN682198
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN682200
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our IKZF3 抗体

Zhu, Shi, Bruins, Wang, Riggs, Porter, Ahmann, de Campos, Braggio, Bergsagel, Stewart: "Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4." in: Blood cancer journal, Vol. 9, Issue 2, pp. 19, (2019) (PubMed).

Kinoshita, Ri, Kanamori, Aoki, Yoshida, Narita, Totani, Ito, Kusumoto, Ishida, Komatsu, Iida: "Potent antitumor effect of combination therapy with sub-optimal doses of Akt inhibitors and pomalidomide plus dexamethasone in multiple myeloma." in: Oncology letters, Vol. 15, Issue 6, pp. 9450-9456, (2018) (PubMed).

Nguyen, Li, Lu, Mamrosh, Lu, Cathers, Deshaies: "p97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 14, pp. 3565-3571, (2017) (PubMed).

Gao, Geng, Song, Lin, Liu, Cai, Cang: "Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase." in: The Journal of biological chemistry, Vol. 292, Issue 9, pp. 3683-3691, (2017) (PubMed).

Uehara, Minoshima, Sagane, Sugi, Mitsuhashi, Yamamoto, Kamiyama, Takahashi, Kotake, Uesugi, Yokoi, Inoue, Yoshida, Mabuchi, Tanaka, Owa: "Selective degradation of splicing factor CAPERα by anticancer sulfonamides." in: Nature chemical biology, Vol. 13, Issue 6, pp. 675-680, (2017) (PubMed).

Costa, Vescovini, Bolzoni, Marchica, Storti, Toscani, Accardi, Notarfranchi, Dalla Palma, Manferdini, Manni, Todaro, Lisignoli, Piazza, Aversa, Giuliani: "Lenalidomide increases human dendritic cell maturation in multiple myeloma patients targeting monocyte differentiation and modulating mesenchymal stromal cell inhibitory properties." in: Oncotarget, Vol. 8, Issue 32, pp. 53053-53067, (2017) (PubMed).

Zhu, Braggio, Shi, Kortuem, Bruins, Schmidt, Chang, Langlais, Luo, Jedlowski, LaPlant, Laumann, Fonseca, Bergsagel, Mikhael, Lacy, Champion, Stewart: "Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma." in: Blood, Vol. 124, Issue 4, pp. 536-45, (2014) (PubMed).

Matulic, Paradzik, Cicin-Sain, Kapitanovic, Dubravcic, Batinic, Antica: "Ikaros family transcription factors in chronic and acute leukemia." in: American journal of hematology, Vol. 84, Issue 6, pp. 375-7, (2009) (PubMed).

Thompson, Cobb, Sabbattini, Meixlsperger, Parelho, Liberg, Taylor, Dillon, Georgopoulos, Jumaa, Smale, Fisher, Merkenschlager: "Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits." in: Immunity, Vol. 26, Issue 3, pp. 335-44, (2007) (PubMed).

Aliases for IKZF3 抗体

IKAROS family zinc finger 3 (IKZF3) 抗体
IKAROS family zinc finger 3 L homeolog (ikzf3.L) 抗体
IKAROS family zinc finger 3 (Ikzf3) 抗体
5830411O07Rik 抗体
AIO 抗体
aio 抗体
AIOLOS 抗体
aiolos 抗体
Aiolos 抗体
IKZF3 抗体
Zfpn1a3 抗体
ZNFN1A3 抗体
znfn1a3 抗体
Znfn1a3 抗体
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