anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) 抗体

The protein encoded by HAVCR1 is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. 再加上,我们可以发HAVCR1 试剂盒 (50)HAVCR1 蛋白 (47)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
HAVCR1 26762 Q96D42
HAVCR1 286934 O54947
HAVCR1 171283 Q5QNS5
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antibodies-online.cn销售最多的anti-HAVCR1 抗体

Showing 10 out of 187 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 ICC, IHC (p), WB 100 μg 4至6个工作日
非结合性 WB WB Suggested Anti-HAVCR1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Human Muscle 100 μL 2至3个工作日
非结合性 WB 100 μg 4至6个工作日
大鼠 非结合性 IHC (fro), IHC (p), WB Anti-TIM 1 antibody, Western blotting Lane 1: SMMC Cell Lysate Lane 2: HELA Cell Lysate Lane 3: PANC Cell Lysate Lane 4: MM231 Cell Lysate Lane 5: MM453 Cell Lysate Anti-TIM 1 antibody, IHC(P) IHC(P): Rat Testis Tissue 100 μg 4至6个工作日
山羊 非结合性 ELISA, WB   100 μg 6至7个工作日
非结合性 IHC, IHC (p), WB Human Testis (formalin-fixed, paraffin-embedded) stained with HAVCR1 antibody ABIN292372 at 2.5-5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-TIM-1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11至14个工作日
非结合性 WB 0.1 mg 6至8个工作日
小鼠 非结合性 ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Mouse Tissue 100 μg 15至18个工作日
非结合性 WB 100 μL 11至14个工作日
非结合性 IHC (p), WB 50 μg 6至8个工作日

引用最多的anti-HAVCR1 抗体

  1. Human Polyclonal HAVCR1 Primary Antibody for ELISA, ICC - ABIN4359752 : Lim, Chan, Lai, Tang, Chow, Lam, Leung: Distinct role of matrix metalloproteinase-3 in kidney injury molecule-1 shedding by kidney proximal tubular epithelial cells. in The international journal of biochemistry & cell biology 2012 (PubMed)
    Show all 11 Pubmed References

  2. Human Monoclonal HAVCR1 Primary Antibody for CyTOF, FACS - ABIN4899579 : Ivie, Fennessey, Sheng, Rubin, McClain: Gene-trap mutagenesis identifies mammalian genes contributing to intoxication by Clostridium perfringens ε-toxin. in PLoS ONE 2011 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal HAVCR1 Primary Antibody for WB - ABIN4359750 : Xu, Cheng, Wen, Oh, Mou, Shi, Xu, Li: Inverse association between T-cell immunoglobulin and mucin domain-1 and T-bet in a mouse model of allergic rhinitis. in The Laryngoscope 2007 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal HAVCR1 Primary Antibody for WB - ABIN541534 : Ichimura, Bonventre, Bailly, Wei, Hession, Cate, Sanicola: Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury. in The Journal of biological chemistry 1998 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal HAVCR1 Primary Antibody for IHC (p), WB - ABIN541533 : Feigelstock, Thompson, Mattoo, Zhang, Kaplan: The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor. in Journal of virology 1998 (PubMed)
    Show all 3 Pubmed References

  6. Mouse (Murine) Polyclonal HAVCR1 Primary Antibody for ICC, IHC - ABIN1077715 : Schindler, Bondeva, Schindler, Claus, Franke, Wolf: Preconditioned suppression of prolyl-hydroxylases attenuates renal injury but increases mortality in septic murine models. in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2016 (PubMed)

  7. Human Polyclonal HAVCR1 Primary Antibody for WB - ABIN3016798 : Adeoye, Asenuga, Oyagbemi, Omobowale, Adedapo: The Protective Effect of the Ethanol Leaf Extract of Andrographis Paniculata on Cisplatin-Induced Acute Kidney Injury in Rats Through nrf2/KIM-1 Signalling Pathway. in Drug research 2018 (PubMed)


Human Hepatitis A Virus Cellular Receptor 1 (HAVCR1) interaction partners

  1. KIM-1 is a specific and stable marker of antemortem tubular injury in kidneys of adults and fetuses despite postmortem autolysis.

  2. uKIM-1 increased significantly after a very short period of exercise. It is not clear if the increase in KIM-1 is caused by post-exercise albuminuria

  3. KIM-1 is the most sensitive biomarker for early detection of acute kidney injury in patients receiving platinum based drugs.

  4. Serum kidney injury molecule 1 and beta2-microglobulin perform as well as larger biomarker panels for prediction of rapid decline in renal function in type 2 diabetes.

  5. The 157insMTTTVP variant of HAVCR1 gene was not associated with more severe outcome of hepatitis A virus infection in an Indian population.

  6. The urinary KIM-1 level corresponds with the severity of renal histological damage and can be a potential reliable predictor of adverse renal outcomes in acute tubular injury (ATI) patients. Moreover, combining urinary and plasma KIM-1 levels can increase the sensitivity and specificity of the diagnosis of severe ATI.

  7. HAVCR1 upregulation might serve as a valuable prognostic marker in terms of OS and RFS in GC patients

  8. We used the CRISPR/Cas9 system to knock-in reporter transgenes at the kidney injury molecule-1 (KIM-1) locus and isolated proximal tubule cell (HK-2) clones. PCR verified targeted knock-in of the luciferase and eGFP reporter at the KIM-1 locus. HK-2-KIM-1 reporter cells responded to various stimuli including hypoxia, cisplatin, and high glucose, indicative of upregulation of KIM-1 expression.

  9. The urinary KIM-1 increases rapidly upon the tubular injury, and its levels are associated with the degree of tubular injury, interstitial fibrosis, and inflammation in the injured kidney.

  10. In conclusion, these findings demonstrate that TIM-1 promotes Japanese encephalitis virus infection as an entry cofactor, and the polymorphism of TIM-1 is associated with Japanese encephalitis virus susceptibility to host cells.

  11. neither the inflammatory biomarker calprotectin, nor the tubular biomarkers NGAL and KIM-1, provide robust prognostic information on the loss of renal function in a heterogeneous CKD population. All of them, however, are candidate prognostic biomarkers in primarily inflammatory renal diseases.

  12. High KIM1 expression is associated with Clear Cell Renal Cell Carcinoma.

  13. Human oligodendrocytes undergo apoptosis when exposed to Sema4A and take up H-ferritin for meeting iron requirements and that these functions are mediated via the Tim-1 receptor. H-ferritin can block Sema4A-mediated cytotoxicity. Sema4A is detectable in the CSF of multiple sclerosis patients and HIV-seropositive persons and can induce oligodendrocyte cell death.

  14. Elevated plasma NT-proBNP and KIM-1 in patients with stage 5 chronic kidney disease (CKD5) undergoing maintenance hemodialysis (HD) and HF (+) (heart failure)CKD5-HD patients suggest that natriuretic peptides and KIM-1 may contribute to the pathogenesis of HF in CKD5-HD patients.

  15. These findings suggest that the TIMD4-HAVCR1 variants may be the genetic risk factors for coronary heart disease and ischemic strok

  16. These studies provide evidence that, in the absence of a functional alpha-dystroglycan, TIM-1 mediates the entry of Lassa virus pseudoviral particles through interactions of virions with the IgV PtdSer-binding pocket of TIM-1.

  17. total flavone of Desmodium styracifolium inhibited HK-2 cell apoptosis and autophagy by regulating KIM-1 via p38/MAPK pathway.

  18. Polymorphism +4259A>C in exon 3 of the TIM-3 gene is associated with susceptibility to multiple sclerosis but polymorphism -1637C>T in the promoter region of TIM-1 is not.

  19. High KIM1 expression is associated with decreased proximal tubular epithelial cell function.

  20. findings show that TIM1 is not an essential cellular receptor for hepatitis A virus entry into cultured cells

Chimpanzee Hepatitis A Virus Cellular Receptor 1 (HAVCR1) interaction partners

  1. Data suggest that T-cell immunoglobulin domain and mucin domain containing protein 1 (TIM1) to be under positive natural selection in primates.

Rhesus Monkey Hepatitis A Virus Cellular Receptor 1 (HAVCR1) interaction partners

  1. Data suggest that T-cell immunoglobulin domain and mucin domain containing protein 1 (TIM1) to be under positive natural selection in primates.

Mouse (Murine) Hepatitis A Virus Cellular Receptor 1 (HAVCR1) interaction partners

  1. Our findings suggest a role for UMOD-dependent inhibition of KIM-1 expression and its apoptotic cell scavenging responses during chronic obstruction-associated tubular injury

  2. findings show that TIM1 is not required for hepatitis A virus (HAV) replication and pathogenesis in permissive strains of mice, although it may facilitate early stages of infection by binding phosphatidylserine on the quasi-enveloped HAV surface

  3. the interaction of TIM4TIM1 was found to promote Th2cell proliferation through enhancing SIRT1 expression in mice with nasal allergic rhinitis.

  4. findings provide evidence for the role of Tim-1 in the induction of a cytokine storm phenomenon and the pathogenesis of Ebola virus disease

  5. Cisplatin enhances kidney injury molecule-1 (Kim-1) gene expression in kidney S3 cells.

  6. By preventing ERK1/2 phosphorylation following renal injury, STAT3 phosphorylation is decreased, leading to less phosphorylated STAT3 within the nucleus, and subsequently less KIM-1 mRNA increases post injury

  7. Study used a previously described highly mobile membrane mimetic membrane in combination with a conventional lipid bilayer model to generate a membrane-bound configuration of Tim1 in silico, identified two possible states for a membrane-bound form of Tim1.

  8. Our data reveal a previously unknown role for Galpha12 in regulating efferocytosis and that renal tubular epithelial cells require KIM-1 to mediate this process.

  9. Urinary L-FABP, NGAL, Kim-1 and albumin levels increased during the acute phase of kidney injury and were significantly correlated with the degree of tubulointerstitial fibrosis during the chronic phase. These markers could detect higher risk of progression to CKD.

  10. Blockade of Tim-1 changes Th1/Th2 balance and reduces circulating regulatory T cells to enhance atherosclerosis in LDL receptor knockout mice.

  11. Our results suggest that KIM-1 is an endogenous protective mechanism against renal ischemia-reperfusion injury

  12. data suggest that TIM-1 signaling plays a direct role in Breg maintenance and induction both under physiological conditions (in response to ACs) and in response to therapy through TIM-1 ligation

  13. Deletion of the mucin domain impaired KIM-1-mediated phagocytic function, resulting in increased proinflammatory cytokine production, decreased antiinflammatory growth factor secretion by proximal epithelial cells, and an increase in tissue macrophages.

  14. Tim-1 is critical for maintaining self-tolerance by regulating IL-10 production in Bregs

  15. blood biomarker that specifically reflects acute and chronic kidney injury

  16. Tim-1 expression was lower in a herpes simplex virus-induced Behcet's disease (BD) mouse model compared to that in asymptomatic BD normal (BDN) mice.

  17. Tim-1-Fc protects cardiac grafts from chronic rejection by suppressing CD4 Th17 development and functionality.

  18. KIM-1 shedding is accelerated by worsening renal cellular injury, and excess soluble KIM-1 competitively inhibits efferocytosis.

  19. Endogenous Tim-1 promotes severe systemic autoimmunity and renal disease MRL-Fas(lpr) mice.

  20. a major P-selectin ligand with a role in T cell trafficking during inflammatory responses and the induction of autoimmune disease

HAVCR1 抗原简介


The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with HAVCR1

  • hepatitis A virus cellular receptor 1 (HAVCR1) 抗体
  • hepatitis A virus cellular receptor 1 (Havcr1) 抗体
  • hepatitis A virus cellular receptor 1 homolog (LOC100226241) 抗体
  • AI503787 抗体
  • HAVCR 抗体
  • HAVCR-1 抗体
  • HAVCR1 抗体
  • KIM-1 抗体
  • Kim1 抗体
  • LOC100226241 抗体
  • TIM 抗体
  • TIM-1 抗体
  • Tim1 抗体
  • TIMD-1 抗体
  • Timd1 抗体

Protein level used designations for HAVCR1

T cell immunoglobin domain and mucin domain protein 1 , T-cell membrane protein 1 , kidney injury molecule 1 , HAVcr-1 , TIMD-1 , hepatitis A virus cellular receptor 1 homolog , t cell immunoglobulin and mucin domain-containing protein 1 , hepatitis A virus cellular receptor 1 , T-cell immunoglobulin and mucin domain containing 1 , t cell membrane protein 1 , T-cell immunoglobulin and mucin domain-containing protein 1

26762 Homo sapiens
286934 Rattus norvegicus
416249 Gallus gallus
462218 Pan troglodytes
612069 Canis lupus familiaris
614846 Bos taurus
715333 Macaca mulatta
100226241 Taeniopygia guttata
100303721 Sus scrofa
171283 Mus musculus
102141332 Macaca fascicularis
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