anti-Hematopoietically Expressed Homeobox (HHEX) 抗体

HHEX encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. 再加上,我们可以发Hematopoietically Expressed Homeobox 蛋白 (10)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
HHEX 3087 Q03014
HHEX 15242 P43120
HHEX 79237  
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Showing 10 out of 107 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 IHC, WB Human Muscle Rabbit Anti-HHEX Antibody  Catalog Number: ARP31443_P050 Formalin Fixed Paraffin Embedded Tissue: Human Adult heart  Observed Staining: Nuclei in adipocytes but not in cardiomyocytes Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 – 2.0 sec Protocol located in Reviews and Data. 100 μL 2至3个工作日
Cow 非结合性 WB WB Suggested Anti-HHEX Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 293T cell lysate 100 μL 2至3个工作日
非结合性 WB WB Suggested Anti-Hhex Antibody Titration:  0.2-1 ug/ml  Positive Control:  Mouse Thymus 100 μL 2至3个工作日
Cow 非结合性 WB WB Suggested Anti-Hhex Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Mouse Muscle 100 μL 2至3个工作日
非结合性 WB 100 μg 4至6个工作日
小鼠 非结合性 IF, WB 100 μL 11至14个工作日
小鼠 非结合性 ELISA, WB HHEX monoclonal antibody (M02), clone 1A5. Western Blot analysis of HHEX expression in human liver. HHEX monoclonal antibody (M02), clone 1A5 Western Blot analysis of HHEX expression in MES-SA/Dx5 100 μg 11至12个工作日
Cow 非结合性 WB 100 μL 11至14个工作日
小鼠 非结合性 IF, IHC, IHC (p) Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL 11至14个工作日
小鼠 非结合性 IF 100 μL 11至14个工作日

引用最多的anti-Hematopoietically Expressed Homeobox 抗体

  1. Human Polyclonal HHEX Primary Antibody for WB - ABIN966283 : Hromas, Radich, Collins: PCR cloning of an orphan homeobox gene (PRH) preferentially expressed in myeloid and liver cells. in Biochemical and biophysical research communications 1993 (PubMed)
    Show all 2 Pubmed References

更多抗Hematopoietically Expressed Homeobox的相互作用对抗体

Xenopus laevis Hematopoietically Expressed Homeobox (HHEX) interaction partners

  1. Data show that knockdown of hematopoietically expressed homeobox (hhex) resulted in a down-regulation of ventral pancreatic precursor 1 (vpp1) expression and a specific loss of the ventral pancreas.

  2. A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer.

Human Hematopoietically Expressed Homeobox (HHEX) interaction partners

  1. Genetic risk scores were calculated by summing the risk alleles of 4 selected single nucleotide polymorphisms, CDKAL1 rs7754840 and rs9460546, HHEX rs5015480, and OAS3

  2. Study clearly demonstrates that rs5015480 genetic variant in HHEX influences fasting glucose levels in Korean women and male heavy smokers.

  3. HHEX is expressed in multiple types of acute myeloid leukemia (AML), with the highest levels seen in t(8;21) AML.

  4. The SNPs in TCF7L2 and HHEX were genotyped by polymerase chain reaction-restriction fragment length polymorphism. There were no significant differences in the distribution of genotypes and alleles between polycystic ovary syndrome cases and controls

  5. Two differentiation-related genes, HHEX and HLX, are promoters of early phase reprogramming toward pluripotency.

  6. This finding highlights the potentially functional alteration with HHEX rs1111875 and rs7923837 polymorphisms may increase colorectal cancer susceptibility.

  7. The aim of this study was to examine the association between HHEX (rs5015480) and PROX1 (rs340874) gene polymorphisms and Gestational diabetes mellitus (GDM) .The HHEX gene rs5015480 C allele may be a risk allele of GDM that is associated with increased BMI during pregnancy

  8. Vascular smooth muscle protein kinase CK2 inhibition suppresses neointima formation via a proline-rich homeodomain-dependent mechanism.

  9. HHEX over expression induced by human cytomegalovirus infection closely associated with vascular proliferative diseases.

  10. The multivariate logistic regression analysis with reference to both alleles and genotypes of CDKAL1 SNPs showed significant association, suggesting an important role for this gene in the T2DM pathophysiology. INTERPRETATION & CONCLUSIONS: A significant association was seen of all the three SNPs of CDKAL1 and CDKN2A/B genes with T2DM but none of the two SNPs of HHEX.

  11. These studies identify uPA-dependent de-repression of vegfr1 and vegfr2 gene transcription through binding to HHEX/PRH as a novel mechanism by which uPA mediates the pro-angiogenic effects of VEGF and identifies a potential new target for control of pathologic angiogenesis.

  12. Low HHEX mutation is associated with Thyroid Dysgenesis.

  13. Data suggest that hematopoietically expressed homeobox protein (HHEX) downmodulation by promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein (PML-RARalpha) is a key event during acute promyelocytic leukemia (APL) pathogenesis.

  14. Hhex binds to the Cdkn2a locus and directly interacts with the Polycomb-repressive complex 2 (PRC2) to enable H3K27me3-mediated epigenetic repression

  15. Data suggest that Hhex is a novel regulator of c-Myc function that limits c-Myc activity in transformed cells.

  16. PRH controls the migration of multiple epithelial cell lineages in part at least through the direct transcriptional regulation of Endoglin

  17. HHEX promotes hepatic specification by repressing EOMES expression.

  18. Data indicate the potential importance of CDKAL1 protein and homeobox protein HHEX in glucose homeostasis in this Alaska Native population with a low prevalence of type 2 diabetes (T2D).

  19. In all the CHD patients, we did not find any causative mutations in the coding region of the HHEX gene.

  20. Tissue-specific knockdown of the HHEX ortholog dHHEX (CG7056) directed metabolic defects and enhanced lethality; for example, fat-body-specific loss of dHHEX led to increased hemolymph glucose and reduced insulin sensitivity

Mouse (Murine) Hematopoietically Expressed Homeobox (HHEX) interaction partners

  1. Hematopoietic stem cells require Hhex to promote PRC2-mediated Cdkn2a repression to enable continued self-renewal and response to hematopoietic stress.

  2. The Hhex evolutionarily conserved non-coding region appears to be a core node for the convergence of the transcription factor network that governs the emergence of Hematopoietic stem cells.

  3. Hhex(-/-) mESCs fail to differentiate from definitive endoderm to hepatic endoderm.

  4. results implicate Hhex in the maintenance of LT-HSCs and in lineage allocation from multipotent progenitors especially in stress hematopoiesis.

  5. Data suggest that Hhex is a novel regulator of c-Myc function that limits c-Myc activity in transformed cells.

  6. Hhex regulates Kit to promote radioresistance of self-renewing thymocytes in Lmo2-transgenic mice.

  7. Hhex is a key regulator of early lymphoid development, functioning, at least in part, via regulation of the cell cycle.

  8. Hhex and Cer1 are indispensable components of the Sox17 pathway for cardiopoiesis.

  9. Hhex as the first transcriptional regulator specifically required for islet delta cells and suggest compromised paracrine control as a contributor to T2DM

  10. Data suggest that GPC3 down-regulates hepatocyte proliferation by binding to hedgehog (HH) and down-regulating the HH signaling pathway and binding with CD81, thus making it unavailable to bind to Hhex and causing its nuclear translocation.

  11. Hex expression and subcellular localization are associated with chondrocyte maturation

  12. Loss of Hhex is associated with reduction in hematopoietic maturation accompanied by reduced proliferation.

  13. the interaction between Hhex and SOX13 may contribute to control Wnt/TCF1 signaling in the early embryo.

  14. identified and characterized a bone morphogenetic protein-responsive element (BRE) within the mouse Hex gene promoter

  15. necessary for B cell development and function and its absence results in a dramatic increase in B220(-)CD19(+) cells

  16. Hex is a novel regulator of hemangioblast differentiation to hematopoietic and endothelial cells.

  17. Hex can act as a T lineage oncogene when misexpressed in hematopoietic precursor cells

  18. Controls production of a diffusible heart-inducing factor.

  19. Hex functions at multiple stages of development within differentiating embryoid bodies and acts as a negative regulator of the hemangioblast and the endothelial lineage

  20. Hex promotes endoderm organogenesis by promoting the transition to a pseudostratified epithelium, which in turn allows hepatoblasts to emerge into the stromal environment and continue differentiating.

Zebrafish Hematopoietically Expressed Homeobox (HHEX) interaction partners

  1. Overall, the data show that HHEX controls blood vessel and lymphatic vessel formation by regulating the VEGFC/FLT4/PROX1 signaling axis.

  2. hhex, nk2.1a, and pax2.1 regulate thyroid growth and differentiation downstream of Nodal-dependent transcription factors.

  3. Data suggest that zebrafish hhex appears to be activated by Wnt/beta-catenin in the dorsal yolk syncytial layer, where bozozok acts in a permissive way to limit repression of hhex by Vega1 and Vega2.

Hematopoietically Expressed Homeobox (HHEX) 抗原简介


This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation.

Gene names and symbols associated with HHEX

  • Homeobox protein PRH (Bm1_31285) 抗体
  • hematopoietically expressed homeobox (hhex) 抗体
  • hematopoietically expressed homeobox (HHEX) 抗体
  • hematopoietically expressed homeobox (Hex1) 抗体
  • hematopoietically expressed homeobox L homeolog (hhex.L) 抗体
  • hematopoietically expressed homeobox (Hhex) 抗体
  • HEX 抗体
  • Hex1 抗体
  • HHEX 抗体
  • hhex-A 抗体
  • Hhex-rs2 抗体
  • HMPH 抗体
  • HOX11L-PEN 抗体
  • Prh 抗体
  • Prhx 抗体
  • PROBOX 抗体
  • tHex 抗体
  • XHex 抗体

Protein level used designations for HHEX

Homeobox protein PRH , hematopoietically-expressed homeobox protein hhex , homeobox protein hex , homeodomain transcription factor , hematopoietically expressed homeobox , hematopoietically-expressed homeobox protein HHEX , homeobox protein HEX , homeobox protein PRH , homeobox, hematopoietically expressed , proline-rich homeodomain-containing transcription factor , hematopoietically expressed homeobox protein , hematopoietically expressed homeobox, related sequence 2 , hematopoietically-expressed homeobox protein Hhex , mHex

6101149 Brugia malayi
100305190 Oncorhynchus mykiss
395060 Xenopus (Silurana) tropicalis
450612 Pan troglodytes
7235725 Branchiostoma floridae
100303530 Saccoglossus kowalevskii
373590 Xenopus laevis
3087 Homo sapiens
608175 Canis lupus familiaris
397232 Sus scrofa
539542 Bos taurus
15242 Mus musculus
79237 Rattus norvegicus
396182 Gallus gallus
30098 Danio rerio
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