Use your antibodies-online credentials, if available.
The protein encoded by HPGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). 再加上，我们可以发HPGDS 抗体 (22) 和 HPGDS 蛋白 (11)和数多这个蛋白质的别的产品。
Showing 4 out of 13 products:
we have utilized a broad-scaled affinity proteomics approach to identify three proteins (CCL5 (显示 CCL5 ELISA试剂盒), HPGDS, and NPSR1 (显示 NPSR1 ELISA试剂盒)) with altered plasma levels in asthmatic children compared to healthy controls, representing the first evaluation of HPGDS and NPSR1 (显示 NPSR1 ELISA试剂盒) in plasma.
the development of a competition binding assay amenable to high-throughput screening (HTS (显示 APCDD1 ELISA试剂盒)) in a scintillation proximity assay (SPA (显示 FASL ELISA试剂盒)) format. This assay was used to screen an in-house compound library of approximately 280,000 compounds for novel H-PGDS inhibitors.
The effect of C. molle alkaloid extract on H-PGDS was studied. The alkaloid extract exhibited a 70% inhibition on H-PGDS with an IC50 of 13.7 mug/ml.
the Val187Ile HPGDS isoenzyme common among African Americans is not associated with colorectal cancer risk
COX-1 and H-PGDS were rapidly ubiquitinated and degraded through the ubiquitin-proteasome system in response to the elevation of the intracellular calcium level
In patients with mixed atrophy, testicular mast cell numbers and phenotypes change with respect to the ability to express COX2 (显示 COX2 ELISA试剂盒) and PGDS (显示 PTGDS ELISA试剂盒)-H.
New polymorphisms of haematopoietic prostaglandin D synthase (显示 PTGDS ELISA试剂盒)
Data suggest that the suppressive effect of hematopoietic prostaglandin D synthase on lung injury could be partly mediated by edema formation and inhibition of genes involved in fibrosis.
X-ray structure of human H-PGDS complexed with an inhibitor, 2-(2'-benzothiazolyl)-5-styryl-3-(4'-phthalhydrazidyl) tetrazolium chloride (BSPT) at 1.9 A resolution in the presence of Mg(2 (显示 MUC7 ELISA试剂盒)+).
PU.1 cooperates with MAPK (显示 MAPK1 ELISA试剂盒)-activated cJun (显示 JUN ELISA试剂盒) to maximally induce L-PGDS (显示 PTGDS ELISA试剂盒) expression in macrophages.
H-PGDS deficiency accelerates the production of SDF-1alpha and the activity of MMP-9 (显示 MMP9 ELISA试剂盒) in the antigen-stimulated intestine. SDF-1alpha receptor blockade or MMP-9 (显示 MMP9 ELISA试剂盒) inhibition relieves the exacerbated mast cell hyperplasia and manifestations observed in H-PGDS(-/-).
HPGDS may play a role in the regulation of inflammation and epithelial cell health within the oviduct.
Data suggest a role for hematopoietic prostaglandin D synthase-produced prostaglandin D(2) in the initial nuclear translocation of SOX9 (显示 SOX9 ELISA试剂盒).
These data suggest that PGD(2) generated via HPGDS has detrimental effects after spinal cord injury and that blocking the activity of this enzyme can be beneficial.
hPGD (显示 HPGD ELISA试剂盒)(2)S-derived cyclopentenone prostaglandins may protect against inflammatory diseases, where T lymphocytes play a pathogenic role, as in rheumatoid arthritis, atopic eczema, and chronic rejection
Our results demonstrated that the neuroprotective effects of HPGDS in our model are mediated by suppression of activation and infiltration of inflammatory cells.
Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes.
, glutathione S-transferase sigma
, glutathione-dependent PGD synthase
, glutathione-dependent PGD synthetase
, glutathione-requiring prostaglandin D synthase
, hematopoietic prostaglandin D2 synthase
, prostaglandin-H2 D-isomerase
, prostaglandin D2 synthase, hematopoietic
, glutathione S-transferase
, prostaglandin D2 synthase 2, hematopoietic
, prostaglandin-D synthase
, hematopoietic prostaglandin D synthase
, hematopoietic prostaglandin D synthase a
, prostaglandin D2 synthase, hematopoietic a