Hematopoietic Prostaglandin D Synthase (HPGDS) ELISA试剂盒

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member.

list all ELISA KIts 基因 基因ID UniProt
 HPGDS HPGDS 27306 O60760
小鼠 HPGDS HPGDS 54486 Q9JHF7
大鼠 HPGDS HPGDS 58962 O35543
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小鼠 0.065 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13至16个工作日
$720.00
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0.09 ng/mL 0.312-20 ng/mL   96 Tests Log in to see 2至3个工作日
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< 34 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Log in to see 11至18个工作日
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小鼠 < 6.8 pg/mL 15.62 pg/mL - 1000 pg/mL   96 Tests Log in to see 11至18个工作日
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大鼠 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11至18个工作日
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0.78-50 ng/mL   96 Tests Log in to see 15至18个工作日
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适于 HPGDS 相互作用对的更多 ELISA 试剂盒

Human Hematopoietic Prostaglandin D Synthase (HPGDS) interaction partners

  1. Thus, our results suggest decreased NK cell-mediated eosinophil regulation, possibly through an increased level of PGD2, as a previously unrecognized link between PG dysregulation and eosinophilic inflammation in CRS.

  2. These observations suggest that tumor cell-derived inflammatory cytokines increase L-PGDS (显示 PTGDS ELISA试剂盒) expression and subsequent PGD2 (显示 PTGDS ELISA试剂盒) production in the tumor endothelial cells (ECs). This PGD2 (显示 PTGDS ELISA试剂盒) acts as a negative regulator of the tumorigenic changes in tumor ECs.

  3. we have utilized a broad-scaled affinity proteomics approach to identify three proteins (CCL5 (显示 CCL5 ELISA试剂盒), HPGDS, and NPSR1 (显示 NPSR1 ELISA试剂盒)) with altered plasma levels in asthmatic children compared to healthy controls, representing the first evaluation of HPGDS and NPSR1 (显示 NPSR1 ELISA试剂盒) in plasma.

  4. the development of a competition binding assay amenable to high-throughput screening (HTS (显示 APCDD1 ELISA试剂盒)) in a scintillation proximity assay (SPA (显示 FASL ELISA试剂盒)) format. This assay was used to screen an in-house compound library of approximately 280,000 compounds for novel H-PGDS inhibitors.

  5. Serum levels of beta trace protein and beta 2 microglobulin (显示 B2M ELISA试剂盒) can be used to predict residual kidney function in hemodialysis patients.

  6. BTP and B2M levels are less affected than serum by amputation, and should be considered for future study of GFR estimation

  7. Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function

  8. levels of L-PGDS (显示 PTGDS ELISA试剂盒) in cervicovaginal secretions of pregnant women at different stages of parturition correlate with preterm birth.

  9. PTGDS (显示 PTGDS ELISA试剂盒) mRNA expression was down-regulated in rapid-cycling bipolar disorder patients in a euthymic, depressive, and manic/hypomanic state compared with healthy control subjects.

  10. Expression of MR and prostaglandin D2 synthase (显示 PTGDS ELISA试剂盒) is strongly correlated in adipose tissues from obese patients.

Mouse (Murine) Hematopoietic Prostaglandin D Synthase (HPGDS) interaction partners

  1. H-PGDS deficiency accelerates the production of SDF-1alpha and the activity of MMP-9 (显示 MMP9 ELISA试剂盒) in the antigen-stimulated intestine. SDF-1alpha receptor blockade or MMP-9 (显示 MMP9 ELISA试剂盒) inhibition relieves the exacerbated mast cell hyperplasia and manifestations observed in H-PGDS(-/-).

  2. HPGDS may play a role in the regulation of inflammation and epithelial cell health within the oviduct.

  3. Data suggest a role for hematopoietic prostaglandin D synthase-produced prostaglandin D(2) in the initial nuclear translocation of SOX9 (显示 SOX9 ELISA试剂盒).

  4. These data suggest that PGD(2) generated via HPGDS has detrimental effects after spinal cord injury and that blocking the activity of this enzyme can be beneficial.

  5. hPGD (显示 HPGD ELISA试剂盒)(2)S-derived cyclopentenone prostaglandins may protect against inflammatory diseases, where T lymphocytes play a pathogenic role, as in rheumatoid arthritis, atopic eczema, and chronic rejection

  6. Our results demonstrated that the neuroprotective effects of HPGDS in our model are mediated by suppression of activation and infiltration of inflammatory cells.

HPGDS 抗原简介

Antigen Summary

The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.

Gene names and symbols associated with HPGDS

  • hematopoietic prostaglandin D synthase (HPGDS) 抗体
  • prostaglandin D2 synthase (PTGDS) 抗体
  • hematopoietic prostaglandin D synthase (hpgds) 抗体
  • hematopoietic prostaglandin D synthase (Hpgds) 抗体
  • hematopoietic prostaglandin D synthase L homeolog (hpgds.L) 抗体
  • gsts 抗体
  • GSTS1-1 抗体
  • H-PGDS 抗体
  • hpgds 抗体
  • hpgds-a 抗体
  • hpgds-b 抗体
  • hpgdsa 抗体
  • L-PGDS 抗体
  • LPGDS 抗体
  • PDS 抗体
  • PGD2 抗体
  • pgds 抗体
  • PGDS2 抗体
  • Ptgds2 抗体
  • XlGSTS1 抗体

Protein level used designations for HPGDS

GST class-sigma , glutathione S-transferase sigma , glutathione-dependent PGD synthase , glutathione-dependent PGD synthetase , glutathione-requiring prostaglandin D synthase , hematopoietic prostaglandin D2 synthase , prostaglandin-H2 D-isomerase , PGD2 synthase , beta-trace protein , cerebrin-28 , glutathione-independent PGD synthase , glutathione-independent PGD synthetase , lipocalin-type prostaglandin D synthase , lipocalin-type prostaglandin-D synthase , prostaglandin D synthase , prostaglandin-D2 synthase , prostaglandin D2 synthase, hematopoietic , glutathione S-transferase , prostaglandin D2 synthase 2, hematopoietic , H-PGDS , prostaglandin-D synthase , hematopoietic prostaglandin D synthase , hematopoietic prostaglandin D synthase a , prostaglandin D2 synthase, hematopoietic a

GENE ID SPECIES
27306 Homo sapiens
5730 Homo sapiens
448666 Xenopus (Silurana) tropicalis
54486 Mus musculus
58962 Rattus norvegicus
395863 Gallus gallus
100139892 Bos taurus
398969 Xenopus laevis
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