HLA Class II DO alpha 蛋白 (HLA-DOA)

HLA-DOA belongs to the HLA class II alpha chain paralogues. 再加上,我们可以发HLA-DOA 抗体 (34)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
HLA-DOA 3111 P06340
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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HLA-DOA 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,

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Human HLA Class II DO alpha (HLA-DOA) interaction partners

  1. Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis

  2. significant association was found between white wine liking and rs9276975:C>T polymorphism in the HLA-DOA gene.

  3. TAP2 (显示 TAP2 蛋白), HLA-DOA, HLA-DOB (显示 HLA-DOB 蛋白), and tapasin (显示 TAPBP 蛋白) loci are novel candidate regions for susceptibility to HCV infection and viral clearance in the Chinese population

  4. HLA-DO regulates surface presentation of human leukocyte antigen class II (显示 HLA-DRB5 蛋白)-restricted antigens on B cell malignancies.

  5. HLA-DOA, HLA-DRA, and HLA-DQA1 associated with spontaneous autoimmunity

  6. HLA-DOA mutations were analyzed for association with autoimmune diseases and B-cell leukemias.

  7. In transgenic mice expressing human HLA-DOA & HLA-DOB from a DC-specific promoter, as DO increased, A(b)-CLIP increased & class II-peptides decreased. DO impaired H-2M function, causing Ag-specific downmodulation of class II Ag processing/presentation.

  8. four novel HLA-DOA alleles, DOA*010106, DOA*0102, DOA*0103, and DOA*0104N, were identified by sequence-based typing

  9. minor allele of the SNP rs9296068 is significantly associated with liver transplantation rejection and with enhanced B-lymphocyte (显示 AKAP17A 蛋白) participation in rejection, likely because of a dysfunctional HLA-DOA gene product.

  10. HLA-DOA polymorphisms are associated with Diabetes Mellitus, Type 1.

蛋白简介HLA-DOA

蛋白简介

HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

Gene names and symbols associated with HLA Class II DO alpha 蛋白 (HLA-DOA)

  • major histocompatibility complex, class II, DO alpha (HLA-DOA)
  • HLA-DNA 蛋白
  • HLA-DZA 蛋白
  • HLADZ 蛋白

Protein level used designations for HLA Class II DO alpha 蛋白 (HLA-DOA)

HLA class II histocompatibility antigen, DO alpha chain , HLA-D0-alpha , MHC DN-alpha , MHC DZ alpha , MHC class II antigen DOA , lymphocyte antigen , major histocompatibility complex, class II, DN alpha

GENE ID SPECIES
3111 Homo sapiens
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