GNRHR 抗体
(Gonadotropin-Releasing Hormone Receptor (GNRHR))
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008].
recommended
GNRHR 适用: 人, 大鼠 WB, ELISA, IHC (p), IHC (fro), ICC, IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
recommended
recommended
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GNRHR 抗体 by 适用
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Reactivity
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Validations
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Datasheet
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Datasheet
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Latest Publications for our GNRHR 抗体
: "Androgen receptor as a prognostic biomarker and therapeutic target in uterine leiomyosarcoma." in: Journal of gynecologic oncology, Vol. 29, Issue 3, pp. e30, (2019) (PubMed).: "Investigation of hormone receptor expression and its prognostic value in endometrial stromal sarcoma." in: Virchows Archiv : an international journal of pathology, Vol. 473, Issue 1, pp. 61-69, (2018) (PubMed).
: "The expression of several reproductive hormone receptors can be modified by perfluorooctane sulfonate (PFOS) in adult male rats." in: Chemosphere, Vol. 155, pp. 488-97, (2016) (PubMed).
: "Effects of di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-ovarian axis in adult female rats." in: Reproductive toxicology (Elmsford, N.Y.), Vol. 46, pp. 141-7, (2014) (PubMed).
: "Expression and transcriptional regulation of the GnRH receptor gene in human neuronal cells." in: Molecular human reproduction, Vol. 11, Issue 11, pp. 837-42, (2006) (PubMed).
: "Characterization of a new upstream GnRH receptor promoter in human ovarian granulosa-luteal cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 7, pp. 1552-64, (2002) (PubMed).
: "Endogenous regulation of the GnRH receptor by GnRH in the human placenta." in: Molecular human reproduction, Vol. 7, Issue 1, pp. 89-95, (2001) (PubMed).
: "Inhibition of gonadotropin-releasing hormone receptor signaling by expression of a splice variant of the human receptor." in: Molecular endocrinology (Baltimore, Md.), Vol. 11, Issue 9, pp. 1305-18, (1997) (PubMed).
: "Brain gonadotropin releasing hormone receptors: localization and regulation." in: Recent progress in hormone research, Vol. 52, pp. 475-90; discussion 490-1, (1997) (PubMed).
: "GnRH receptor mRNA expression by in-situ hybridization in the primate pituitary and ovary." in: Molecular human reproduction, Vol. 2, Issue 2, pp. 117-21, (1997) (PubMed).
Aliases for GNRHR 抗体
gonadotropin releasing hormone receptor (GNRHR) 抗体gonadotropin releasing hormone receptor (Gnrhr) 抗体
gonadotropin releasing hormone receptor (gnrhr) 抗体
gonadotropin-releasing hormone receptor (gnrh-r) 抗体
GH1 抗体
gnrh-r 抗体
GNRHR 抗体
GNRHR1 抗体
GNRHR1/III 抗体
GNRHR2 抗体
gnrhr3/ii 抗体
GRHR 抗体
HH7 抗体
LHRHR 抗体
Lhrhr 抗体
LRHR 抗体
xgnrhr 抗体
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