Glycoprotein M6A 蛋白 (GPM6A)

GPM6A encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. 再加上,我们可以发Glycoprotein M6A 抗体 (101)Glycoprotein M6A 试剂盒 (4)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
GPM6A 2823 P51674
GPM6A 234267 P35802
大鼠 GPM6A GPM6A 306439 Q812E9
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Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50至55个工作日
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Insect Cells rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50至55个工作日
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
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GPM6A 蛋白 by Origin and Source

Origin 在表达 标记
Human ,
,
Mouse (Murine)

更多Glycoprotein M6A (GPM6A)互动伙伴

Human Glycoprotein M6A (GPM6A) interaction partners

  1. HDAC5 (显示 HDAC5 蛋白) emerges as a cellular conductor of MEF2C (显示 MEF2C 蛋白) and M6a activity and is regulated by miR (显示 MLXIP 蛋白)-124 and miR (显示 MLXIP 蛋白)-9 to control neurite development.

  2. findings thus indicate a critical role of correct GPM6A/M6 levels for cognitive function and support a role of the GPM6A duplication for the patient's phenotype

  3. Data indicate that neuronal membrane glycoproteins GPM6A and GPM6B (显示 GPM6B 蛋白) may act as novel oncogenes in the development of lymphoid leukemia.

  4. loosing dynamic regulation of neuronal GPM6A expression poses a genetic risk for claustrophobia

  5. Results indicate that M6a modulates mu-opioid receptor (显示 OPRM1 蛋白) endocytosis and post-endocytotic sorting and has an important role in receptor regulation.

  6. Results suggest that expression level of GPM6A is associated with the differentiation and neuronal migration of neurons derived from undifferentiated human embryonic stem cells.

Mouse (Murine) Glycoprotein M6A (GPM6A) interaction partners

  1. GPM6a induces the clustering of lipid rafts and acts as a signal transducer that responds to extracellular signals.

  2. This study demonistrated that M6a is essential for the support of neurite extension in developmental brain.

  3. analysis of actin-independent behavior and membrane deformation exhibited by the four-transmembrane protein M6a

  4. M6a-deficient axons grow actively but are not growth suppressed by antibodies bound to four-transmembrane actin-based glycoprotein M6a concentrated on the edge of the axon growth cone.

  5. expression of shRNA against GPM6A markedly reduced the expression of neuroectodermal-associated genes (OTX1, Lmx1b (显示 LMX1B 蛋白), En1 (显示 EN1 蛋白), Pax2, Pax5 (显示 PAX5 蛋白), Sox1 (显示 SOX1 蛋白), Sox2 (显示 SOX2 蛋白), and Wnt1 (显示 WNT1 蛋白)), and also the number of neural stem cells (NSC) derived from D3mshM6A cells

  6. These results suggest that M6a plays a role in retinal development by regulating neurites, and it may also function to modulate synaptic activities in the adult retina.

Zebrafish Glycoprotein M6A (GPM6A) interaction partners

蛋白简介Glycoprotein M6A (GPM6A)

蛋白简介

This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

Gene names and symbols associated with Glycoprotein M6A 蛋白 (GPM6A)

  • glycoprotein M6A (GPM6A)
  • glycoprotein m6a (Gpm6a)
  • glycoprotein M6A (gpm6a)
  • glycoprotein M6A (Gpm6a)
  • glycoprotein M6A L homeolog (gpm6a.L)
  • glycoprotein M6Ab (gpm6ab)
  • DMbeta/M6a 蛋白
  • DMbeta2 蛋白
  • EMA 蛋白
  • gm6a 蛋白
  • Gpm6 蛋白
  • gpm6a 蛋白
  • gpm6a-A 蛋白
  • M6a 蛋白
  • MGC145278 蛋白

Protein level used designations for Glycoprotein M6A 蛋白 (GPM6A)

neuronal membrane glycoprotein M6-a , neuronal proteolipid GPM6A , M6a , glycoprotein M6A , glycoprotein M6A L homeolog , glycoprotein M6A, myelin PLP-related membrane protein DM beta

GENE ID SPECIES
2823 Homo sapiens
234267 Mus musculus
306439 Rattus norvegicus
422569 Gallus gallus
475641 Canis lupus familiaris
507389 Bos taurus
698488 Macaca mulatta
742345 Pan troglodytes
780312 Xenopus (Silurana) tropicalis
100172611 Pongo abelii
100229820 Taeniopygia guttata
100359107 Oryctolagus cuniculus
100725735 Cavia porcellus
394384 Xenopus laevis
407734 Danio rerio
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