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Induces apoptosis.. 再加上，我们可以发Gasdermin A 蛋白 (4)和数多这个蛋白质的别的产品。
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modest changes (8-13%) in promoter methylation levels of ZPBP2 (显示 ZPBP2 抗体) and GSDMA may cause substantial changes in RNA levels and allelic expression of ZPBP2 (显示 ZPBP2 抗体) and ORMDL3 (显示 ORMDL3 抗体) is mediated by DNA methylation (显示 HELLS 抗体)
GSDMA was identified as a susceptibility gene for systemic sclerosis.
we investigated the association between GSDMA and GSDMB (显示 GSDMB 抗体) variants and the incidence of adult and childhood asthma among Jordanians.An association between the GSDMB (显示 GSDMB 抗体) T/C single nucleotide polymorphism (SNP) genotype and the incidence of childhood asthma was found
The local genotype influences methylation levels at SLC22A5 (显示 SLC22A5 抗体) and ZPBP2 (显示 ZPBP2 抗体) promoters independently of the asthma status. Further studies are necessary to confirm the relationship between GSDMA-ZPBP2 (显示 ZPBP2 抗体) and SLC22A5 (显示 SLC22A5 抗体) methylation and asthma in females and males separately.
Based on our results and published findings on GSDMA, GSDMB, LRRC3C, and related proteins, we propose that this locus in part affects IBD susceptibility via effects on apoptosis and cell proliferation
Study identified significantly white blood cell count (WBC) level associated SNPs of three separate genes GSDMA, MED24 (显示 MED22 抗体), and PSMD3 (显示 PSMD3 抗体) in European continent (EA) subjects.
The GSDMA (rs7212938) and GSDMB (显示 GSDMB 抗体) (rs7216389) polymorphisms are associated with asthma susceptibility and intermediate asthma phenotypes.
Results suggest an association of 17q21 polymorphisms with ORMDL3 (显示 ORMDL3 抗体), GSDMA expression, and IL-17 (显示 IL17A 抗体) secretion early in life. These observations may imply a functional role of the 17q21 locus affecting T-cell development during immune maturation.
The present data suggest that TGF-beta (显示 TGFB1 抗体), LMO1 (显示 LMO1 抗体), possibly RUNX3 (显示 RUNX3 抗体), and GSDM form a regulatory pathway for directing the pit (显示 IRF6 抗体) cells to apoptosis.
Study investigated the expression pattern of the GSDM family genes in the upper gastrointestinal epithelium and cancers.
, gasdermin A1
, gasdermin A