G-2 and S-Phase Expressed 1 (GTSE1) ELISA试剂盒

The protein encoded by GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. 再加上,我们可以发GTSE1 抗体 (74)GTSE1 蛋白 (3)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
GTSE1 29870 Q8R080
GTSE1 51512 Q9NYZ3
大鼠 GTSE1 GTSE1 300126  
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小鼠 < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11至18个工作日
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< 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11至18个工作日
$810.17
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Human G-2 and S-Phase Expressed 1 (GTSE1) interaction partners

  1. Knockdown of GTSE1 obviously suppressed the proliferation, migration, and invasion capacity whereas increasing GTSE1 led to the opposite trend, which suggested that GTSE1 could serve as a potential therapeutic target for bladder cancer. GTSE1 overexpression in bladder cancer might participate in the regulation of FoxM1/CCNB1 expression via the induction of the transfer of p53 to cytoplasm

  2. High expression of GTSE1 is commonly noted in hepatocellular carcinoma (HCC) and is closely correlated with migration and invasion by epithelial-to-mesenchymal transition modulation. Activated GTSE1 significantly interferes with chemotherapy efficacy and influences the probability of survival of patients with HCC.

  3. G2 and S-phase expressed 1 (GTSE1) expression promotes AM progression and correlates with clinical outcomes of patients with acral melanoma (AM), and may represent a promising therapeutic target to suppress AM progression.

  4. GTSE1 is expressed exclusively in late G2 and M phase. From nuclear envelope breakdown until anaphase onset, GTSE1 binds preferentially to the most stable mitotic spindle microtubules and promotes their turnover.

  5. Results indicated for the first time that overexpression of GTSE1 was involved in the progress of HCC, enhancing proliferation and promoting cell invasion in HCC cells.

  6. GTSE1 inhibition of MCAK activity regulates the balance of MT stability that determines the fidelity of chromosome alignment, segregation, and chromosomal stability.

  7. Study identifies GTSE1 as a biomarker for cisplatin resistance in gastric cancer cells and suggests its repressive role in cisplatin induced apoptosis making it a potential therapeutic target for better clinical management of gastric cancer patients.

  8. GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration.

  9. GTSE1 is overexpressed dramatically in lung cancer patients' tissues.

  10. Data show that G2 and S-phase-expressed 1 (GTSE1) protein, a negative regulator of p53, is required for G2 checkpoint recovery and that Plk1 phosphorylation of GTSE1 promotes its nuclear localization.

  11. hGTSE-1 mediated-p21(CIP1/WAF1) stabilization is clearly involved in the ability of cells to counteract cytotoxicity induced by the microtubule poison paclitaxel.

  12. GTSE-1 controls DNA damage-induced apoptosis by affecting p53 function

  13. requires an intact nuclear export signal and functional Mdm2 for the regulation of p53

GTSE1 抗原简介

Antigen Summary

The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

Gene names and symbols associated with GTSE1

  • G2 and S-phase expressed 1 S homeolog (gtse1.S) 抗体
  • G2 and S-phase expressed 1 (gtse1) 抗体
  • G2 and S-phase expressed 1 (GTSE1) 抗体
  • G-2 and S-phase expressed 1 (gtse1) 抗体
  • G2 and S-phase expressed 1 L homeolog (gtse1.L) 抗体
  • G two S phase expressed protein 1 (Gtse1) 抗体
  • G-2 and S-phase expressed 1 (Gtse1) 抗体
  • B99 抗体
  • fb70b04 抗体
  • fj88g09 抗体
  • Gtse-1 抗体
  • GTSE1 抗体
  • MGC81588 抗体
  • MGC89498 抗体
  • MGC114722 抗体
  • RGD1563164 抗体
  • wu:fb70b04 抗体
  • wu:fj88g09 抗体
  • wu:fy65d12 抗体

Protein level used designations for GTSE1

G-2 and S-phase expressed 1 , G2 and S phase-expressed protein 1 , G2 and S phase-expressed protein 1-like , g2 and S phase-expressed protein 1-like , protein B99 homolog , G two S phase expressed protein 1

GENE ID SPECIES
447452 Xenopus laevis
448634 Xenopus (Silurana) tropicalis
458984 Pan troglodytes
553652 Danio rerio
734417 Xenopus laevis
100386121 Callithrix jacchus
100455508 Pongo abelii
100579683 Nomascus leucogenys
29870 Mus musculus
425204 Gallus gallus
51512 Homo sapiens
608855 Canis lupus familiaris
507901 Bos taurus
300126 Rattus norvegicus
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