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The protein encoded by FUT1 is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. 再加上，我们可以发FUT1 蛋白 (16)和数多这个蛋白质的别的产品。
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Cow (Bovine) Polyclonal FUT1 Primary Antibody for WB - ABIN2781768
Kondoh, Tateno, Hirabayashi, Yasumoto, Nakao, Oishi: Molecular clock regulates daily ?1-2-fucosylation of NCAM within mouse secondary olfactory neurons. in The Journal of biological chemistry 2014
Fut1 plays an important role in regulating angiogenesis and ICAM-1 (显示 ICAM1 抗体) expression in inflammatory arthritis.
We found that Fut1 mRNA and Fut4 (显示 FUT4 抗体) mRNA were upregulated, while Fut2 (显示 FUT2 抗体) mRNA and Fut9 (显示 FUT9 抗体) mRNA were downregulated by androgen in the caput epididymis.
fucosyltransferase (Fut)-deficient (Fut1, Fut2 (显示 FUT2 抗体) and Fut4 (显示 FUT4 抗体)) mice which lack LeX (显示 FUT4 抗体) or LeY antigen are still fertile.
These results indicate that Fut2 (显示 FUT2 抗体)-mediated fucosylated epithelial cells (F-ECs) share M cell-related fucosylated molecules but maintain distinctive EC characteristics, Fut1 is, therefore, a reliable marker for M cells.
FUT1 is essential for fucosylation of glycolipid GA1 in the pancreas.
In null mutant mice lacking FUT1, the absence of blood group (显示 DARC 抗体) H carbohydrate resulted in the delayed maturation of the glomerular layer of the main olfactory bulb.
Vasculogenesis was the most clearly affected by FUT1 expression, suggesting that tumor angiomorphogenesis may depend on E-selectin (显示 SELE 抗体)-mediated interaction between HCC (显示 FAM126A 抗体) and endothelial cells, the inhibition of which remarkably retards tumor growth.
High FUT1 expression is associated with breast cancer.
downregulation of FUT1, which leads to the perinuclear localization of LAMP-1 (显示 LAMP1 抗体) and 2, is correlated with increased rate of autophagic flux by decreasing mTOR (显示 FRAP1 抗体) signaling and increasing autolysosome formation.
The H blood group (显示 DARC 抗体) system is defined by a terminal fucose residue found on red blood cells and in secretions formed by the action of alpha-1,2-fucosyltransferases 1 (alpha2FucT1) and 2 (alpha2FucT2), respectively. Mutant alleles of the corresponding FUT1 and FUT2 (显示 FUT2 抗体) genes result in either a H- phenotype (Bombay phenotype) or a weak H phenotype (para-Bombay). Review.
Two novel FUT1 mutations have been identified in the proband's FUT1 gene. The insertion mutation in the FUT1 that caused a shift of the open reading frame and formed a termination codon early at Amino Acid Position 334 may be the main reason for H deficiency in this case.
Protein O-fucosyltransferase 1 (显示 POFUT1 抗体) promotes trophoblast cell proliferation by activating MAPK (显示 MAPK1 抗体) and PI3K (显示 PIK3CA 抗体)/Akt (显示 AKT1 抗体) signaling pathways.[poFUT1 (显示 POFUT1 抗体)]
Data suggest that the identification of genes in response to alpha1,2-fucosyl transferase (FUT1) may provide a theoretical basis for the investigations of the molecular mechanism of ovarian cancer.
alpha(1,2)-fucosyltransferase activity is involved in the development of multidrug resistance of chronic myeloid leukemia (显示 BCL11A 抗体) cells probably through FUT1 regulated the activity of EGFR (显示 EGFR 抗体)/MAPK (显示 MAPK1 抗体) signaling pathway and the expression of P-gp (显示 ABCB4 抗体).
data confirm the hypothesis that the h2 allele is linked to Se(357, 716), and the concurrence of unique FUT1 and FUT2 (显示 FUT2 抗体) mutations is geographically specific.
We show that fut1 in RA synovial fibroblasts is important in angiogenesis, leukocyte-synovial fibroblast adhesion, and synovial fibroblast proliferation
FUT1 expression levels and low FUT2 (显示 FUT2 抗体) expression levels in the intestines of Sutai pigs affected FUT1 and FUT2 (显示 FUT2 抗体) enzymes, the synthesis of type 2 H and type 1 H antigens, and E. coli F18 (显示 MAMLD1 抗体) adhesion. Moreover, low FUT2 (显示 FUT2 抗体) expression levels conferred resistance to E. coli F18 (显示 MAMLD1 抗体).
Polymorphism of FUT1 and MUC4 (显示 MUC4 抗体) associated with resistance to colibacteriosis was determined.
The 5'-flanking region of the FUT1 gene (-1150 to +50 bp) exhibited promoter activity and the -1150-bp to -849-bp region showed negative regulation of the gene.
Studied the beneficial effects of alpha (1,2)-fucosyltransferase (FUT1) M307 (A) on piglet survival on commercial farms. Piglet survival for individuals with the AA genotype was almost two-fold greater than for GG individuals.
The results indicated that Sutai pigs with the AA genotype in M307 of FUT1 gene have relatively strong general disease resistance ability in piglets.
The mutation at M307 in the FUT1 gene determines susceptibility of small intestinal epithelium to E. coli F18 (显示 MAMLD1 抗体) adhesion in Sutai piglets.
FUT1 mutations might play a role in pig infection by multi-pathogens, and the AA may be a favourable genotype for increasing the resistance to disease.
Beneficial genotype of swine FUT1 gene governing resistance to E. coli F18 (显示 MAMLD1 抗体) is associated with important economic traits
transgenic male pigs were produced that possess an alpha alpha-1,3-galactosyltransferase knockout allele and express a randomly inserted human alpha 1,2-fucosylosyltransferase transgene
Results showed that the genetic polymorphisms of the FUT1 locus were only detected in the 3 exotic pig breeds and indicated that FUT 1 gene and the type of breeds significantly affected total number born.
Data show that si-RNA induced down-regulation of FUT1 and FUT2 (显示 FUT2 抗体) reduced expression of fucosylated nucleolin (显示 NCL 抗体) glycoforms and their exposure at the cell surface.
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group.
GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1
, H transferase
, alpha(1,2)FT 1
, beta-galactoside alpha-1,2-fucosyltransferase
, galactoside 2-alpha-L-fucosyltransferase 1
, alpha 1,2-fucosyltransferase A
, alpha 12-fucosyltransferase
, alpha12-fucosyltransferase a
, fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase)
, alpha (1,2) fucosyltransferase
, blood group H alpha 2-fucosyltransferase
, alpha(1-2) fucosyltransferase 1
, fucosyltransferase 1