anti-Dihydropyrimidinase-Like 5 (DPYSL5) 抗体

DPYSL5 encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. 再加上,我们可以发Dihydropyrimidinase-Like 5 试剂盒 (15)Dihydropyrimidinase-Like 5 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
DPYSL5 56896 Q9BPU6
DPYSL5 65208 Q9JHU0
DPYSL5 65254 Q9EQF6
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Showing 10 out of 51 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 IHC (p), IHC, WB Western Blot: CRMP5 Antibody [NBP1-33419] - Sample (30 ug of whole cell lysate) A: H1299 B: Raji 7. 5% SDS PAGE; antibody diluted at 1:1000. Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-33419] - Paraffin-embedded SW480 xenograft, using antibody at 1:500 dilution. 0.1 mL Log in to see 8至11个工作日
$514.63
详细
小鼠 非结合性 ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) . Dilution: 1:500~1000 Western Blot analysis of DPYSL5 expression in transfected 293T cell line by DPYSL5 monoclonal antibody (M02), clone 2G4.Lane 1: DPYSL5 transfected lysate(61.4 KDa).Lane 2: Non-transfected lysate. Dilution: 1:500~1000 100 μg Log in to see 8至11个工作日
$461.00
详细
非结合性 IHC, IHC (p) Immunohistochemistry: CRMP5 Antibody [NBP1-85461] - Staining of human lateral ventricle shows strong cytoplasmic and nuclear positivity in neuronal cells. Immunohistochemistry-Paraffin: CRMP5 Antibody  - Staining of human lateral ventricle shows moderate cytoplasmic positivity in neuronal cells. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
Cow 大鼠 非结合性 ICC, IF, IHC, IHC (fro), WB Immunohistochemistry-Paraffin: CRMP5 Antibody (CR-3) [ABIN2614984] - Biopsies of deparaffinized Human glioma tissue. Immunohistochemistry-Paraffin: CRMP5 Antibody (CR-3) [ABIN2614984] - Biopsies of deparaffinized Human tonsil tissue. 0.1 mL Log in to see 7至9个工作日
$444.19
详细
Cow 大鼠 非结合性 ICC, IF, IHC, IHC (fro), IHC (p), WB Immunohistochemistry-Paraffin: CRMP5 Antibody (CR-1) [ABIN2614995] - Biopsies of deparaffinized Human brain tissue. Immunohistochemistry-Paraffin: CRMP5 Antibody (CR-1) [ABIN2614995] - Biopsies of deparaffinized Human glioma tissue. 0.1 mL Log in to see 7至9个工作日
$444.19
详细
小鼠 非结合性 IF, WB Western blot analysis of extracts of various cell lines, using DPYSL5 antibody. 100 μL Log in to see 16 Days
$334.02
详细
小鼠 非结合性 ELISA, WB 100 μg Log in to see 11至14个工作日
$537.17
详细
小鼠 非结合性 IF, ELISA, WB DPYSL5 monoclonal antibody (M04), clone 2D10. Western Blot analysis of DPYSL5 expression in rat brain. Detection limit for recombinant GST tagged DPYSL5 is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 11至12个工作日
$440.00
详细
小鼠 非结合性 IF/ICC, WB Western blot analysis of extracts of various cell lines, using DPYSL5 antibody (ABIN3049350). 100 μL Log in to see 11至16个工作日
$426.40
详细

更多抗Dihydropyrimidinase-Like 5的相互作用对抗体

Human Dihydropyrimidinase-Like 5 (DPYSL5) interaction partners

  1. Study describes the relevance of DRP5 during osteosarcoma development. DRP5 was upregulated in osteosarcoma specimens and cell lines and shown to function via the downstream MMPs. Inhibition of DRP5 suppressed the growth of cancer cells in vitro and in vivo, and high expression levels of DRP5 were associated with poor prognosis in osteosarcoma patients.

  2. Our findings suggest that CRMP5 serves as a major mediator of Notch (显示 NOTCH1 抗体) signaling and Akt (显示 AKT1 抗体) activation by controlling the degradation of the Notch (显示 NOTCH1 抗体) receptor, with implications for defining a biomarker signature in glioblastoma

  3. present study suggested that CRAM (显示 CCRL2 抗体) could be a clinical prognostic marker for patients with cervical cancer

  4. study elucidates a novel regulatory mechanism that utilizes CRMP5-induced mitophagy to orchestrate proper dendrite outgrowth and neuronal function.

  5. identified residues that are crucial for determining the preference for hetero-oligomer or homo-oligomer formation. In spite of being the CRMP family member most closely related to dihydropyrimidinase (显示 DPYS 抗体), CRMP-5 does not have amidohydrolase activity.

  6. New CRMP5 isoform present in the nucleus is associated with Glioma.

  7. CRMP-5-IgG defines a paraneoplastic ophthalmological entity of combined optic neuritis and retinitis with vitreous inflammatory cells.

  8. CRMP-5 autoimmune myelopathy and occult neoplasia are important considerations in patients with insidiously progressive myelopathy, especially with known cancer risk.

  9. We describe a patient with optic neuropathy and vitritis as the only clinical manifestations of paraneoplastic optic neuropathy secondary to lung cancer marked by an extremely high titer of CRMP-5 antibody.

  10. findings point at CRMP5 as a novel marker for distinguishing between highly aggressive neuroendocrine carcinoma and the other lung cancers.

Mouse (Murine) Dihydropyrimidinase-Like 5 (DPYSL5) interaction partners

  1. study elucidates a novel regulatory mechanism that utilizes CRMP5-induced mitophagy to orchestrate proper dendrite outgrowth and neuronal function.

  2. CRMP5-deficient mice show abnormal Schwann process extension resulting in abnormal cell-axon segregation, indicating that CRMP5 is involved in the morphologic adaptation of Schwann cells to surround axons.

  3. These findings provide the first evidence that CRMP5 is involved in the generation and survival of newly generated neurons in areas of the adult brain with a high level of activity-dependent neuronal plasticity.

  4. Data show that CRMP5 is involved in the development, maintenance and synaptic plasticity of Purkinje cells.

  5. The CRMP5 binding to tubulin (显示 TUBB 抗体) modulates CRMP2 (显示 DPYSL2 抗体) regulation of neurite outgrowth and neuronal polarity during brain development.

  6. CRAM regulates filopodial dynamics and growth cone development, thereby restricting the response of growth cone to repulsive guidance cues

  7. In the olfactory bulb, CRMP1 (显示 CRMP1 抗体), CRMP2 (显示 DPYSL2 抗体) and CRMP5 are abundant in neuronal progenitors of the subependymal layer and in differentiating interneurons.

  8. Our results are therefore consistent with a role for CRMP5 in neuronal process extension.We conclude that expression of CRMP5 is consistent with a dynamic implicit role in forebrain development.

  9. Hypoxia-ischemia (HI)induces dephosphorylation of CRMPs (CRMP1 (显示 CRMP1 抗体), 2, and 5) in neonatal brain. Hypophosphorylated CRMPs might be implicated in the pathogenesis of HI-related neurological disorders.

Dihydropyrimidinase-Like 5 (DPYSL5) 抗原简介

蛋白简介

This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with DPYSL5

  • dihydropyrimidinase like 5 (DPYSL5) 抗体
  • dihydropyrimidinase-like 5 (Dpysl5) 抗体
  • Dihydropyrimidinase-related protein 5 (dpyl5) 抗体
  • dihydropyrimidinase-like 5a (dpysl5a) 抗体
  • dihydropyrimidinase like 5 (dpysl5) 抗体
  • dihydropyrimidinase like 5 (Dpysl5) 抗体
  • dihydropyrimidinase-like 5b (dpysl5b) 抗体
  • CRAM 抗体
  • CRMP-5 抗体
  • CRMP-5a 抗体
  • CRMP-5b 抗体
  • Crmp5 抗体
  • crmp5.1 抗体
  • crmp5.2 抗体
  • DPYSL5 抗体
  • fc28b06 抗体
  • im:7146614 抗体
  • si:ch211-152c2.6 抗体
  • Ulip6 抗体
  • wu:fc28b06 抗体

Protein level used designations for DPYSL5

CRMP3-associated molecule , DRP-5 , ULIP-6 , UNC33-like phosphoprotein 6 , collapsin response mediator protein 5 , collapsin response mediator protein-5 , dihydropyrimidinase-related protein 5 , dihydropyrimidinase-like 5 , Dihydropyrimidinase-related protein 5 , dihydropyrimidinase-related protein 5-like , collapsin response mediator protein 5.2

GENE ID SPECIES
56896 Homo sapiens
65208 Rattus norvegicus
65254 Mus musculus
483004 Canis lupus familiaris
699648 Macaca mulatta
100126171 Bos taurus
100196759 Salmo salar
100353506 Oryctolagus cuniculus
324416 Danio rerio
100030914 Monodelphis domestica
100071300 Equus caballus
100386950 Callithrix jacchus
100478389 Ailuropoda melanoleuca
100496348 Xenopus (Silurana) tropicalis
100511810 Sus scrofa
100558703 Anolis carolinensis
100598354 Nomascus leucogenys
100725488 Cavia porcellus
553410 Danio rerio
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