DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).[supplied by OMIM, Mar 2008].
Sengerová, Allerston, Abu, Lee, Hartley, Kiakos, Schofield, Hartley, Gileadi, McHugh: "Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases." in: The Journal of biological chemistry, Vol. 287, Issue 31, pp. 26254-67, (2012) (PubMed).
Aliases for DCLRE1B 抗体
DNA cross-link repair 1B (DCLRE1B) 抗体 DNA cross-link repair 1B (Dclre1b) 抗体 DNA cross-link repair 1B (dclre1b) 抗体 AI452214 抗体 APOLLO 抗体 Apollo 抗体 im:6894074 抗体 mSNM1B 抗体 SNM1B 抗体 SNMIB 抗体 zgc:154089 抗体