anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) 抗体

CYP2D6 encodes a member of the cytochrome P450 superfamily of enzymes. 再加上,我们可以发Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 蛋白 (14)Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 试剂盒 (13)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CYP2D6 171522 Q64680
CYP2D6 1565 P10635
CYP2D6    
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antibodies-online.cn销售最多的anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 抗体

Showing 10 out of 134 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-CYP2D6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>OVCAR-3 cell lysate WB Suggested Anti-CYP2D6 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: OVCAR-3 cell lysate <br /> CYP2D6 is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 IHC, WB WB Suggested Anti-CYP2D6 <br /> Antibody Titration: 2.5 µg/mL <br /> Positive Control: Human Liver 100 μL Log in to see 2至3个工作日
$229.00
详细
非结合性 WB Western blot analysis of Cytochrome P450 2D6 expression in MCF7 (A), NIH3T3 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 IP, WB Western blot analysis of Cytochrome P450 2D6 expression in A431 (A), K562 (B), HuvEc (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 WB Western blot analysis of Cytochrome P450 2D6 expression in MCF7 (A), NIH3T3 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 IP, WB Western blot analysis of Cytochrome P450 2D6 expression in A431 (A), K562 (B), HuvEc (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 ELISA, WB Western blot analysis of extracts from 293/HuvEc/MCF-7 cells, using Cytochrome P450 2D6 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 ELISA, WB Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2D6 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 WB   200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 IHC (p), WB   100 μg Log in to see 4至6个工作日
$280.00
详细

通过反应活性、应用领域、克隆类型和共轭标记 CYP2D6 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 抗体

  1. Human Polyclonal CYP2D6 Primary Antibody for IHC (p), WB - ABIN658441 : Gao, Zhang, Cui, Akinyi: Comparison of Paeoniflorin and Albiflorin on Human CYP3A4 and CYP2D6. in Evidence-based complementary and alternative medicine : eCAM 2015 (PubMed)

更多抗Cytochrome P450, Family 2, Subfamily D, Polypeptide 6的相互作用对抗体

Human Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) interaction partners

  1. The study results indicated the good response pattern was influenced by the concentration of donepezil, but not by APOE (显示 APOE 抗体) and CYP2D6 polymorphisms.

  2. tamoxifen biotransformation to endoxifen is highly dependent on CYP2D6 activity; however, it is unclear whether there is an association between CYP2D6 genotype or endoxifen concentration and tamoxifen efficacy.

  3. even though the available recommendations are against the CYP2D6 screening, the negative results of clinical trials may have been biased by issues in data collection, analysis and interpretation.

  4. CYP2D6 protein and activity levels did not differ significantly between the genotypes (CYP2D6*1/*1, *1/*10, and *10/*10 genotypes) in the small intestine of the Japanese population.

  5. genetic association studies in Chinese population: Data suggest that genetic polymorphisms and mutations in CYP2D6 are associated with alterations in metabolism of the anti-hemangioma medication hemangeol; some genetic alterations exclude hemangeol as a substrate for CYP2D6.

  6. Genetic polymorphisms of some CYP (显示 PPIG 抗体) enzymes, especially CYP2D6*10, could affect enzyme activity in hepatocellular carcinoma

  7. This study demonstrates that the GSTP1 (显示 GSTP1 抗体)*B and *C allelic variants may be considered a candidate gene for AD[Alzheimer disease]. It can be suggested that although CYP2D6*4 polymorphism is not a risk of AD[Alzheimer disease], the CYP2D6*4 and GSTP1 (显示 GSTP1 抗体) polymorphism may interact with beta-HCH (显示 DOCK2 抗体), dieldrin, and copper to influence the risk of AD [Alzheimer disease].

  8. The number of functional CYP2D6 genes was positively associated with an increased risk of tardive dyskinesia, and suggest that this could be due to the generation of neurotoxic metabolites.

  9. study found the 1846A allele frequency in Tatars was lower than in Russians, but the difference was not statistically significant; a statistically significant association between the development of extrapyramidal disorders (EPD) during haloperidol monotherapy and heterozygous 1846GA genotype and 1846A allele frequency was revealed among all schizophrenic patients and among those of Tatar ethnicity

  10. The loss of function CYP2D6*3 (g.2549delA, rs35742686) genetic variant was found and contained the CYP2D6 g.2470T>C (rs17002852) variation, which had an allele frequency of 2.47%.

Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) 抗原简介

蛋白简介

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug\; sparteine and propafenone, both anti-arrythmic drugs\; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population\; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CYP2D6

  • cytochrome 2D6 (CYP2D6) 抗体
  • cytochrome P450 2D6 (CYP2D6) 抗体
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) 抗体
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6-b) 抗体
  • cytochrome P450 family 2 subfamily D member 6 S homeolog (cyp2d6.S) 抗体
  • cytochrome P450 family 2 subfamily D member 6 (cyp2d6) 抗体
  • cytochrome P450, family 2, subfamily d, polypeptide 4 (Cyp2d4) 抗体
  • cytochrome P450 family 2 subfamily D member 6 (CYP2D6) 抗体
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D14) 抗体
  • CPD6 抗体
  • CYP2D 抗体
  • cyp2d2 抗体
  • Cyp2d4v1 抗体
  • Cyp2d4v2 抗体
  • CYP2D6 抗体
  • cyp2d6-a 抗体
  • CYP2D7AP 抗体
  • CYP2D7BP 抗体
  • CYP2D7P2 抗体
  • CYP2D8P2 抗体
  • Cyp2d18 抗体
  • Cyp2d22 抗体
  • CYP2D42 抗体
  • CYP2DL1 抗体
  • CYPIID6 抗体
  • MGC64445 抗体
  • P450-DB1 抗体
  • P450C2D 抗体
  • P450DB1 抗体

Protein level used designations for CYP2D6

cytochrome P450 2D6 , cytochrome P450 CYP2D42 , cytochrome P450, family 2, subfamily D, polypeptide 6 , CYPIID18 , CYPIID4 , Cytochrome P450, subfamily IID4 , P450 2D-29/2D-35 , P450-CMF3 , P450-DB4 , cytochrome P450 2D-29 , cytochrome P450 2D-35 , cytochrome P450 2D4 , cytochrome P450 2d18 , cytochrome P450, family 2, subfamily d, polypeptide 22 , cytochrome P450, subfamily 2D, polypeptide 6 , cytochrome P450, subfamily IID, polypeptide 6 , cytochrome P450-CMF3 , cytochrome P450-DB4 , debrisoquine 4-hydroxylase , cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2 , cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2 , cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1 , cytochrome P450-DB1 , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , CYPIID14 , cytochrome P450 2D14 , CYPIID6

GENE ID SPECIES
100500743 Felis catus
100568286 Ovis aries
678691 Macaca mulatta
379479 Xenopus laevis
446878 Xenopus laevis
548436 Xenopus (Silurana) tropicalis
171522 Rattus norvegicus
1565 Homo sapiens
282211 Bos taurus
470228 Pan troglodytes
anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) 抗体 精选生产商
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