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Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. 再加上，我们可以发CYBB 抗体 (114) 和 CYBB 蛋白 (6)和数多这个蛋白质的别的产品。
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Human CYBB ELISA Kit for Sandwich ELISA - ABIN418998
Tassone, Perticone, Sciacqua, Mafrici, Settino, Malara, Mollace, Sesti, Perticone: Low dose of acetylsalicylic acid and oxidative stress-mediated endothelial dysfunction in diabetes: a short-term evaluation. in Acta diabetologica 2015
Rat (Rattus) CYBB ELISA Kit for Sandwich ELISA - ABIN433568
Du, Wang, Wang: Role of RhoA/MERK1/ERK1/2/iNOS signaling in ocular ischemic syndrome. in Graefe's archive for clinical and experimental ophthalmology 2016
The nox1 (显示 NOX1 ELISA试剂盒), nox2/cybb expression in zebrafish during early nervous system development from 12 to 48 hours post fertilization
Data indicate that NADPH oxidase (显示 NOX1 ELISA试剂盒) NOx2 inhibition attenuates endoplasmic reticulum (ER) stress and apoptosis.
Nox2 activity efficiently contributes to the mechanism of oxidative stress-induced (显示 SQSTM1 ELISA试剂盒) increase in premature aging conferred by doxorubicin. The importance of modulation of Nox2 in human EPCs could reveal a useful tool to restore endothelial progenitor cells physiological function and properties.
We examined the pattern of NOX expression in spinal cords of patients and mouse models of ALS (显示 IGFALS ELISA试剂盒) and analyzed the impact of genetic deletion of the NOX1 (显示 NOX1 ELISA试剂盒) and 2 isoforms as well as pharmacological NOX inhibition in the SOD1 (显示 SOD1 ELISA试剂盒)(G93A) ALS (显示 IGFALS ELISA试剂盒) mouse model.In contrast to previous publications, survival of SOD1 (显示 SOD1 ELISA试剂盒)(G93A) mice was not modified upon breeding with constitutive NOX1 (显示 NOX1 ELISA试剂盒) and NOX2 deficient mice.
Recent studies reveal that AKT2 (显示 AKT2 ELISA试剂盒)-NOX2 signaling has critical roles in Ca mobilization, ROS (显示 ROS1 ELISA试剂盒) generation, degranulation, and control of the ligand-binding function of cell surface molecules, thereby promoting heterotypic cell-cell interactions in thromboinflammation.
Study demonstrate that Nox2 signaling via inactivation of phosphatase and tensin homolog and activation of the PI3K (显示 PIK3CA ELISA试剂盒)/Akt (显示 AKT1 ELISA试剂盒) pathway leads to membrane ruffling and macropinocytosis.
Our findings indicate that Nox2 deficiency results in exaggerated experimental asthma, which is caused by enhanced Th2 effector function in a T-cell-intrinsic manner.
In a family study of a patient with chronic granulomatous disease, the mutation in the CYBB gene was confirmed to be pathogenic, and the three variants in the CYBA gene were benign.
Finally, overexpression of miR34a in EBNA1-expressing SNU719 cells induced typical apoptosis, suggesting that reactivation of miR34a in EBNA1-expressing gastric cancer cells could be a strategy for treatment of EBV-infected gastric cancer cells.
NOX2 expression was significantly higher in the cortex of asphyctic suicide subjects than in non-suicidal asphyxia and controls.
Acute myeloid leukemia (显示 BCL11A ELISA试剂盒) cells -derived NOX2 drives transfer of mitochondria via the generation of superoxide.
NOX2, NOX4 (显示 NOX4 ELISA试剂盒), and mitochondrial-derived reactive oxygen species contribute to angiopoietin-1 (显示 ANGPT1 ELISA试剂盒) signaling and angiogenic responses in endothelial cells.
Data indicate that the efficiency of NADPH oxidase (显示 NOX1 ELISA试剂盒) enzymatic activity is higher at endoplasmic reticulum (ER).
A p47(phox) and Src kinase (显示 CSK ELISA试剂盒) activation of peroxide production by Nox2 appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C (显示 PKC ELISA试剂盒)
Role of Protein Kinase C (显示 PKC ELISA试剂盒) and Nox2-Derived Reactive Oxygen Species Formation in the Activation and Maturation of Dendritic Cells by Phorbol Ester and Lipopolysaccharide.
this study shows that neutrophil pyroptosis mediates pathology of Pseudomonas aeruginosa lung infection in the absence of the NADPH oxidase (显示 NOX1 ELISA试剂盒) NOX2
Data indicate that increased NADPH oxidase (显示 NOX1 ELISA试剂盒) activity after traumatic brain injury drives M1-like activation in microglia/macrophages that contributes to inflammatory-mediated neurodegeneration.
Neurofibromin (显示 NF1 ELISA试剂盒) regulates macrophage superoxide production via p21Ras.Neurofibromin-deficient smooth muscle cells are sensitive to oxidative stress.NADPH oxidase 2 is required for NF1 (显示 NF1 ELISA试剂盒) arterial stenosis.Neurofibromatosis type 1 patients have evidence of chronic oxidative stress.
We examined the pattern of NOX expression in spinal cords of patients and mouse models of ALS and analyzed the impact of genetic deletion of the NOX1 (显示 NOX1 ELISA试剂盒) and 2 isoforms as well as pharmacological NOX inhibition in the SOD1 (显示 SOD1 ELISA试剂盒)(G93A) ALS mouse model.In contrast to previous publications, survival of SOD1 (显示 SOD1 ELISA试剂盒)(G93A) mice was not modified upon breeding with constitutive NOX1 (显示 NOX1 ELISA试剂盒) and NOX2 deficient mice.
Spinal cord injury leads to a significant increase in NOX2 expression. The reduction in M2 polarization is associated with a peak in NOX2 expression.
NOX2 has a role in leukocyte activation and in thrombus formation
mice deficient in reactive oxygen species production by NOX2 due to the absence of the gp91 subunit had significantly more severe pathology in the later stages of infection with Leishmania amazonensis
indicate that following traumatic brain injury NOX2 inhibition promotes a robust anti-inflammatory response in macrophages/microglia that is mediated by the IL-10 (显示 IL10 ELISA试剂盒)/STAT3 (显示 STAT3 ELISA试剂盒) signaling pathway
The results suggest that Nrf2 (显示 NFE2L2 ELISA试剂盒) is an important regulator of the retinal milieu during tissue ischemia, and that the Nrf2 (显示 NFE2L2 ELISA试剂盒)/NOX2 balance may play a critical role in determining the fate of ischemic revascularization.
These results suggested that resveratrol strongly enhances the RA-induced O2(-)-generating activity via up-regulation of gp91-phox gene expression in U937 cells.
sub-vasomotor concentration of ET-1 (显示 EDN1 ELISA试剂盒) leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 kinase-mediated production of superoxide from NADPH oxidase (显示 NOX1 ELISA试剂盒) following ETA receptor activation
Reactive oxygen species generated by NADPH oxidase (显示 NOX1 ELISA试剂盒) contribute to the aberrant pulmonary arterial responses in piglets exposed to 3 days of hypoxia.
Upregulation of PPAR-gamma and NADPH oxidases are involved in restenosis.
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase\; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
cytochrome b-245, beta polypeptide
, NADPH oxidase 2
, cytochrome b-245, beta polypeptide (chronic granulomatous disease)
, Cytochrome b-245 heavy chain
, NADPH oxidase heavy chain subunit
, NADPH oxidase 1
, NADPH oxidase flavocytochrome b subunit
, cytochrome b-245 heavy chain
, cytochrome b(558) subunit beta
, cytochrome b558 subunit beta
, heme-binding membrane glycoprotein gp91phox
, neutrophil cytochrome b 91 kDa polypeptide
, p22 phagocyte B-cytochrome
, superoxide-generating NADPH oxidase heavy chain subunit
, endothelial type gp91-phox
, predicted NADPH oxidase-2