anti-Complement Component 3a Receptor 1 (C3AR1) 抗体

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. 再加上,我们可以发C3AR1 试剂盒 (16)C3AR1 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
C3AR1 719 Q16581
C3AR1 12267 O09047
C3AR1 84007 O55197
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antibodies-online.cn销售最多的anti-C3AR1 抗体

Showing 10 out of 98 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
大鼠 小鼠 FITC IHC (fro), FACS 0.1 mg 6至8个工作日
$335.50
详细
非结合性 IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using C3AR1 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of COS7 cells, using C3AR1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2至3个工作日
$302.50
详细
非结合性 IHC, IHC (p) 50 μg 11至14个工作日
$484.00
详细
非结合性 IHC, IHC (p) 50 μg 11至14个工作日
$484.00
详细
非结合性 ELISA, WB Western blot analysis of C3AR1 using 293 whole cell lysates 100 μL 11至12个工作日
$390.77
详细
大鼠 小鼠 Biotin IHC (fro), FACS   0.1 mg 6至8个工作日
$335.50
详细
大鼠 小鼠 PE IHC (fro), FACS   50 μg 6至8个工作日
$335.50
详细
大鼠 小鼠 非结合性 IHC (fro), FACS   0.25 mg 6至8个工作日
$335.50
详细
小鼠 非结合性 FACS, WB Western Blot analysis of C3AR1 expression in transfected 293T cell line by C3AR1 MaxPab polyclonal antibody.Lane 1: C3AR1 transfected lysate(53.02 KDa).Lane 2: Non-transfected lysate. FACS analysis of negative control 293 cells (Black) and C3AR1 expressing 293 cells (Green) using C3AR1 purified MaxPab mouse polyclonal antibody. 50 μg 11至12个工作日
$364.00
详细
非结合性 IF (p), IHC (p), WB 293T lysates probed with C3a Receptor Polyclonal Antibody, Unconjugated  at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C. A549 lysates probed with C3a Receptor Polyclonal Antibody, Unconjugated  at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C. 100 μL 3至7个工作日
$329.45
详细

引用最多的anti-C3AR1 抗体

  1. Human Polyclonal C3AR1 Primary Antibody for IHC, IHC (p) - ABIN4299887 : Gu, Mickler, Cummings, Sandusky, Weber, Gracon, Woodruff, Wilkes, Vittal: Crosstalk between TGF-β1 and complement activation augments epithelial injury in pulmonary fibrosis. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal C3AR1 Primary Antibody for IHC (fro), FACS - ABIN2477790 : Rosenquist: Lingual sulcoplasty with a modified preparation technique. in International journal of oral surgery 1979 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal C3AR1 Primary Antibody for FACS - ABIN2477792 : Zwirner, Götze, Begemann, Kapp, Kirchhoff, Werfel: Evaluation of C3a receptor expression on human leucocytes by the use of novel monoclonal antibodies. in Immunology 2000 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal C3AR1 Primary Antibody for FACS - ABIN2477794 : Werfel, Kirchhoff, Wittmann, Begemann, Kapp, Heidenreich, Götze, Zwirner: Activated human T lymphocytes express a functional C3a receptor. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 4 Pubmed References

  5. Human Polyclonal C3AR1 Primary Antibody for IF (p), IHC (p) - ABIN682213 : Shinjyo, de Pablo, Pekny, Pekna: Complement Peptide C3a Promotes Astrocyte Survival in Response to Ischemic Stress. in Molecular neurobiology 2015 (PubMed)

更多抗C3AR1的相互作用对抗体

Zebrafish Complement Component 3a Receptor 1 (C3AR1) interaction partners

  1. Neural crest cells are coattracted via the complement fragment C3a and its receptor C3aR, revealing an unexpected role of complement proteins in early vertebrate development.

Human Complement Component 3a Receptor 1 (C3AR1) interaction partners

  1. this study shows that C3AR1 expression on M2 macrophages is down-regulated by stimulating the histamine H4 receptor and the IL-4 receptor

  2. Anaphylatoxin C3a has novel roles involved in regulating platelet function and thrombus formation.

  3. This study demonstrate a crucial role for activation of the C3-C3aR network in mediating neuroinflammation and tau pathology.

  4. This study aimed to investigate the role of C3aR and C5aR in these two diseases...Our data indicates that increased C3aR expression may lead to over activation of the Th17 cell response and may therefore contribute to the pathogenesis of Behcet's disease (BD) and Vogt-Koyanagi-Harada disease (VKH).

  5. C3aR has roles in platelet function, thrombus formation and in vivo hemostasis

  6. C3aR-positive cells are found more often in patients with inflammatory cardiomyopathy. The relevance of C3aR-positive cells in patients with non-ischaemic cardiomyopathy should be further evaluated as potential predictors or modulators of adverse cardiac remodelling, the substrate of progressive heart failure.

  7. Studies indicate that the complement response lie the active fragments, C3a and C5a, acting through their specific receptors, C3aR, C5aR1 and C5aR2 to direct the cellular response to inflammation.

  8. High C3aR1 expression is associated with acute myeloid leukemia-M2.

  9. these findings suggest a critical role for C3a through autocrine/paracrine induction of C3aR in the pathogenesis of cigarette smoke-induced sterile inflammation and provide new therapeutic targets for the treatment of emphysema.

  10. Medulloblastoma cells express C3aR, and siRNA-mediated knockdown of C3aR inhibits proliferation of these cells in vitro.

  11. Observed a positive correlation between the expression of anaphylatoxin-receptors C3aR and C5aR with platelet activation in patients with coronary artery disease.

  12. The obesity-induced down-regulation of complement C3 and C3aR which is specific to subcutaneous adipose tissue.

  13. In patients with IgAN, urinary and renal C3a and C5a and renal expression of C3aR and C5aR are significantly correlated with the activity and severity of renal injury.

  14. C3aR and CD46 activation via intrinsic generation of their respective ligands is an integral part of human Th1 (but not Th2) immunity.

  15. functional regulation of C3aR by NHERFs in human mast cells

  16. significantly decreased expression of C3aR mRNA and protein expression in placentas with preeclampsia compared to controls

  17. study demonstrates that although C3a causes phosphorylation of its receptor at multiple sites, Ser459, Thr463, Ser465, Thr466 and Ser470 participate in C3aR desensitization

  18. Complement C3a receptor activation contributes to the pathogenesis of preeclampsia.

  19. a new level of complexity for C3aR regulation

  20. shows that both beta-arrestin-1 and beta-arrestin-2 play a novel and shared role in inhibiting G protein-dependent ERK1/2 phosphorylation. These findings reveal a new level of complexity for C3aR regulation by beta-arrestins in human mast cells

Mouse (Murine) Complement Component 3a Receptor 1 (C3AR1) interaction partners

  1. C3aR and C5aR1 are potent regulators of ethanol-induced adipose inflammation in murine model of alcohol-related liver disease (ALD). C5aR1 modulates the impact of chronic ethanol on the content of the adipose secretome, likely contributing to intra-organ injury in ALD.

  2. Anaphylatoxin C3a has novel roles involved in regulating platelet function and thrombus formation.

  3. C3aR has roles in platelet function, thrombus formation and in vivo hemostasis

  4. C3aR(-/-) animals also have altered neural progenitor cell proliferation, but demonstrate an opposing phenotype to animals subjected to pharmacological blockade of C3aR.

  5. Development of burn-induced mechanical allodynia, thermal allodynia, weight bearing changes and edema was assessed in C3aR(-/-), C5aR1(-/-) and C5aR2(-/-) mice and compared to their wild type controls over three days. Burn-induced mechanical allodynia, thermal allodynia and weight bearing changes developed normally C3aR(-/-), C5aR1(-/-) and C5aR2(-/-) mice.

  6. Complement component 3a receptor 1 role in the lung cancer progression.

  7. The complement 3a receptor (C3aR1) participates in microglial signaling under pathological conditions and was recently shown to be activated by the neuropeptide TLQP-21.

  8. whilst the C3aR modulates some elements of disease pathogenesis, overall it is not critical in effector responses and glomerular injury caused by autoimmunity to MPO

  9. study provided detailed insights into the C3aR expression pattern in immune and stromal cells under steady-state conditions

  10. proposal that C3aR activation alters the tumor inflammatory milieu, thereby promoting tumor growth

  11. The roles of C3, CfB, and C3a receptor in the severity of S. aureus induced septic arthritis are reported.

  12. increased circulating lipopolysaccharide induces upregulation of complement C3a receptor on neutrophils and activation of the complement cascade.

  13. showed that C3a receptor/C5a receptor-deficient mice developed much less severe uveitis than did control mice using all retinal examination methods

  14. these findings suggest a critical role for C3a through autocrine/paracrine induction of C3aR in the pathogenesis of cigarette smoke-induced sterile inflammation and provide new therapeutic targets for the treatment of emphysema.

  15. C3a/C3aR signaling during host immune response suppresses Fas expression and caspase-3 activity while increasing Bcl-2 proto-oncogene protein expression, providing protection to myeloid and lymphoid cells against L. monocytogenes-induced apoptosis.

  16. This study indicated that C3a and C5a-mediated functions are not critical to the development of experimental autoimmune uveitis.

  17. The binding of TLQP-21 to C3AR1 not only has effects on signaling but also modulates cellular functions

  18. C3a receptor promotes viral containment in mice inoculated with vaccinia virus at sites of allergic skin inflammation.

  19. The role of the anaphylatoxin C3a receptor in acute dextran sulfate sodium-induced colitis in mice, was investigated.

  20. ALI in H5N1-infected mice was caused by excessive complement activation, as demonstrated by deposition of C3, C5b-9, and MBL-C in lung tissue, and by up-regulation of MBL-associated serine protease-2 and the complement receptors C3aR and C5aR.

C3AR1 抗原简介

蛋白简介

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity).

Gene names and symbols associated with C3AR1

  • C3a anaphylatoxin chemotactic receptor (c3ar1) 抗体
  • complement C3a receptor 1 (C3AR1) 抗体
  • complement component 3a receptor 1 (C3ar1) 抗体
  • complement C3a receptor 1 (C3ar1) 抗体
  • AZ3B 抗体
  • C3a-R 抗体
  • C3AR 抗体
  • c3ar1 抗体
  • HNFAG09 抗体

Protein level used designations for C3AR1

c3a anaphylatoxin chemotactic receptor , C3AR , C3a anaphylatoxin chemotactic receptor , C3a-R , complement component 3a receptor 1 , complement component 3 receptor 1 , anaphylatoxin C3a receptor

GENE ID SPECIES
794255 Danio rerio
100136104 Oncorhynchus mykiss
100171704 Pongo abelii
466942 Pan troglodytes
716086 Macaca mulatta
100231704 Taeniopygia guttata
719 Homo sapiens
12267 Mus musculus
84007 Rattus norvegicus
100351157 Oryctolagus cuniculus
100379246 Cavia porcellus
486704 Canis lupus familiaris
540702 Bos taurus
418198 Gallus gallus
101104226 Ovis aries
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