anti-Choline Kinase beta (CHKB) 抗体

Choline kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to phosphocholine/phosphoethanolamine. 再加上,我们可以发Choline Kinase beta 蛋白 (11)Choline Kinase beta 试剂盒 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CHKB 1120 Q9Y259
CHKB 29367 O54783
CHKB 12651 O55229
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antibodies-online.cn销售最多的anti-Choline Kinase beta 抗体

Showing 10 out of 42 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IHC, WB Immunohistochemical analysis of CHKB staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated wit Western blot analysis of CHKB expression in HepG2 (A), U2OS (B) whole cell lysates. 200 μL Log in to see 13至14个工作日
非结合性 ELISA, WB Western blot analysis of extracts from HepG2/A549 cells, using CHKB Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
山羊 非结合性 ELISA, WB   0.1 mg Log in to see 6至7个工作日
非结合性 ELISA, ICC, IF, WB Western blot analysis of extracts from HepG2 cells using CHKB antibody. ABIN6274550 staining HepG2 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. 100 μL Log in to see 11至12个工作日
非结合性 IHC, IHC (p), WB Immunohistochemistry-Paraffin: ethanolamine kinase Antibody [NBP1-31606] - H358 xenograft. Western Blot: ethanolamine kinase Antibody [NBP1-31606] - Sample(30 ug whole cell lysate)A:A431 B:Hep G2 10% SDS PAGE, antibody diluted at 1:1000. 0.1 mL Log in to see 8至11个工作日
Hamster 非结合性 WB Antibody is used in Western blot to detect EKI1 in CHO cell lysate. 400 μL Log in to see 2至3个工作日
非结合性 IHC, IHC (p) Immunohistochemistry: ethanolamine kinase Antibody [NBP2-33292] - Pancreatic cancer Immunohistochemistry: ethanolamine kinase Antibody [NBP2-33292] - Immunohistochemical staining of human kidney shows cytoplasmic and nuclear positivity in cells in tubules. 0.1 mL Log in to see 10至13个工作日
山羊 非结合性 ELISA   100 μg Log in to see 11至14个工作日
小鼠 非结合性 IF, WB Western Blot analysis of CHKB expression in transfected 293T cell line by CHKB MaxPab polyclonal antibody.Lane 1: CHKB transfected lysate(43.45 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to CHKB on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Log in to see 11至12个工作日
非结合性 ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: Choline Kinase beta Antibody [NBP1-85632] - Immunofluorescent staining of human cell line U-2 OS shows positivity in cytoplasm. Antibody staining is shown in green. Immunohistochemistry: Choline Kinase beta Antibody [NBP1-85632] - Staining of human thyroid gland shows strong positivity in glandular cells. 0.1 mL Log in to see 10至13个工作日

引用最多的anti-Choline Kinase beta 抗体

  1. Dog (Canine) Polyclonal CHKB Primary Antibody for ELISA - ABIN449837 : Aoyama, Liao, Ishidate: Structure and function of choline kinase isoforms in mammalian cells. in Progress in lipid research 2004 (PubMed)

更多抗Choline Kinase beta的相互作用对抗体

Human Choline Kinase beta (CHKB) interaction partners

  1. findings suggest that CKbeta, in concert with CKalpha, and depending on its phosphorylation status, might play a critical role as a druggable target in carcinogenesis

  2. The whole exome sequencing revealed a novel homozygous missense mutation in the Choline Kinase-Beta (CHKB) gene in exon 9.

  3. A new form of congenital muscular dystrophy with multisystem involvement and characteristic mitochondrial structural changes, due to choline kinase beta gene defects has been characterized.

  4. A novel silent variant in the choline kinase beta causing muscular dystrophy.

  5. Its mutations cause congenital muscular dystrophy.[Review]

  6. study identified a novel haplotype consisting of the indel variation, which had not been detected in previous studies in Japanese and Korean populations, and observed four single-nucleotide polymorphisms in CHKB/CPT1B

  7. CHKB encodes choline kinase beta, an enzyme that catalyzes the first de-novo biosynthetic step of phosphatidylcholine, the most abundant phospholipid in the eukaryotic membrane [review]

  8. CHKB activity was reduced in all three patients, significant reduction in choline:N-acetyl aspartate and choline:creatine ratios in keeping with a general decrease in the amount of choline and phosphocholine-based substrate

  9. The study extends on the observation of a strong multiethnic association of polymorphisms in the TCRA and P2RY11 with narcolepsy, but does not confirm the association of CPT1B/CHKB (rs5770917) in the Chinese population.

  10. homozygous or compound heterozygous mutations in the gene encoding choline kinase beta were identified in individulas with congenital muscular dystrophy.

  11. kinetic studies revealed that HC-3 is a much more potent inhibitor for ChoKalpha isoforms (alpha1 and alpha2) compared with ChoKbeta.

  12. ChoKalpha and ChoKbeta isoforms have different physiological roles and implications in human carcinogenesis

  13. A single nucleotide polymorphism located between CPT1B and CHKB, was associated with narcolepsy in Japanese (rs5770917[C], odds ratio (OR) = 1.79, combined P = 4.4 x 10(-7)) and other ancestry groups (OR = 1.40, P = 0.02).

  14. Japanese CNS hypersomnias (essential hypersomnia: EHS) other than narcolepsy with cataplexy was significantly associated with SNP rs5770917 (located between CPT1B and CHKB) and HLA-DRB1*1501-DQB1*0602 haplotype

Mouse (Murine) Choline Kinase beta (CHKB) interaction partners

  1. CHKB is a new modulator of bone homeostasis

  2. Our data indicate that choline kinase beta plays an important role in endochondral bone formation by modulating growth plate physiology.

  3. Loss of choline kinase beta in skeletal muscle causes mitochondrial dysfunction and increased mitophagy.

  4. Experimental evidence for the presence of heteromeric ChoK/EtnK in any source. The activity of ChoK/EtnK in the cell is controlled not only by the level of each isoform but also by their combination to form the active oligomer complex.

  5. choline kinase beta is the first enzyme in phosphatidylcholine biosynthesis and has a role in rostrocaudal muscular dystrophy

  6. Mutation of the corresponding D276 of CK-beta to A276 did not show any effect on either its homo- or hetero-dimerization but it caused a strong inhibition of CK activity in either case.

  7. The hindlimb muscular dystrophy in Chkb -/- mice is due to attenuated phosphatidylcholine biosynthesis and enhanced catabolism of phosphatidylcholine.

Choline Kinase beta (CHKB) 抗原简介


Choline kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to phosphocholine/phosphoethanolamine. This is the first enzyme in the biosynthesis of phosphatidylcholine/phosphatidylethanolamine in all animal cells. The highly purified CKs from mammalian sources and their recombinant gene products have been shown to have EK activity also, indicating that both activities reside on the same protein. The choline kinase-like protein encoded by CHKL belongs to the choline/ethanolamine kinase family\; however, its exact function is not known. Read-through transcripts are expressed from this locus that include exons from the downstream CPT1B locus.

Gene names and symbols associated with anti-Choline Kinase beta (CHKB) 抗体

  • choline kinase beta (CHKB) 抗体
  • choline kinase beta (Chkb) 抗体
  • choline kinase beta (chkb) 抗体
  • Chetk 抗体
  • Chkl 抗体
  • Ck 抗体
  • Ck/Ek 抗体
  • Ck/Ek-beta 抗体
  • Ckb 抗体
  • Ckekb 抗体
  • Ek 抗体
  • EKB 抗体
  • fc21g05 抗体
  • MDCMC 抗体
  • si:ch211-218c17.2 抗体
  • wu:fc21g05 抗体

Protein level used designations for anti-Choline Kinase beta (CHKB) 抗体

choline kinase-like protein , choline/ethanolamine kinase , ethanolamine kinase beta , choline kinase beta , CK , CKB , CKEKB , EK , choline/ethanolamine kinase beta , ethanolamine kinase , choline/ethanolamine kinase-b , choline/ethanolaminekinase

1120 Homo sapiens
100353391 Oryctolagus cuniculus
606800 Canis lupus familiaris
29367 Rattus norvegicus
12651 Mus musculus
100505461 Sus scrofa
536213 Bos taurus
563589 Danio rerio
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