anti-Chemokine (C-X-C Motif) Ligand 10 (CXCL10) 抗体

CXCL10 encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. 再加上,我们可以发CXCL10 蛋白 (86)CXCL10 试剂盒 (68)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CXCL10 3627 P02778
CXCL10 15945 P17515
CXCL10 245920 P48973
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antibodies-online.cn销售最多的anti-CXCL10 抗体

Showing 10 out of 306 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 ELISA, WB Observed bind size: 34KD 100 μg 4至6个工作日
小鼠 非结合性 ELISA, WB Anti- IP10 Picoband antibody, Western blottingAll lanes: Anti IP10  at 0.5ug/ml  Lane 1: Mouse Ovary Tissue Lysate at 50ug  Lane 2: HEPA Whole Cell Lysate at 40ug Predicted bind size: 11KD Observed bind size: 19KD 100 μg 4至6个工作日
Cow 非结合性 ELISA, WB Western blot using  protein-A purified anti-bovine CXCL10 antibody shows detection of recombinant bovine CXCL10 at 9.3 kDa (arrowhead) raised in yeast. The protein was purified and resolved by SDS-PAGE, then transferred to PVDF membrane. Membrane was blocked with 3% BSA (BSA-30, diluted 1:10), and probed with 1 µg/mL primary antibody overnight at 4°C. After washing, membrane was probed with Conjugated Goat Anti-Rabbit IgG  for 45 min at room temperature. 100 μg 5至7个工作日
非结合性 IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain labeled with Anti-CXCL10 Polyclonal Antibody, Unconjugated (ABIN687442) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rat lung labeled with Anti-CXCL10 Polyclonal Antibody, Unconjugated (ABIN687442) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL 3至7个工作日
非结合性 EIA, Func, WB   50 μg 6至8个工作日
大鼠 非结合性 ELISA, Neut, WB 100 μg 11至14个工作日
非结合性 ELISA, Neut, WB 100 μg 11至14个工作日
小鼠 非结合性 ICC, IF, WB 100 μg 11至14个工作日
非结合性 ELISA, IHC, WB Western blot analysis of extracts of HeLa, using CXCL10 antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276682 at 1/100 staining Human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11至12个工作日
非结合性 IHC (p), WB Anti-IP10 antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue Anti-IP10 antibody, Western blotting Lane 1: Recombinant Human CXCL10 Protein 10ng Lane 2: Recombinant Human CXCL10 Protein 5ng Lane 3: Recombinant Human CXCL10 Protein 2.5ng 100 μg 4至6个工作日

引用最多的anti-CXCL10 抗体

  1. Human Monoclonal CXCL10 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899706 : Lauw, Dekkers, te Velde, Speelman, Levi, Kurimoto, Hack, van Deventer, van der Poll: Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees. in The Journal of infectious diseases 1999 (PubMed)
    Show all 25 Pubmed References

  2. Human Polyclonal CXCL10 Primary Antibody for CyTOF, FACS - ABIN4899708 : Keane, Donnelly, Belperio, Goodman, Dy, Burdick, Fishbein, Strieter: Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 18 Pubmed References

  3. Human Polyclonal CXCL10 Primary Antibody for ELISA (Detection), FACS - ABIN4900661 : Gounni Abdelilah, Wellemans, Agouli, Guenounou, Hamid, Beck, Lamkhioued: Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. in Clinical immunology (Orlando, Fla.) 2006 (PubMed)
    Show all 15 Pubmed References

  4. Human Monoclonal CXCL10 Primary Antibody for IA, IHC (fro) - ABIN2191895 : Hamamdzic, Phillips-Dorsett, Altman-Hamamdzic, London, London: Reovirus triggers cell type-specific proinflammatory responses dependent on the autocrine action of IFN-beta. in American journal of physiology. Lung cellular and molecular physiology 2001 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal CXCL10 Primary Antibody for IA, IHC (fro) - ABIN2191896 : Giustizieri, Albanesi, Scarponi, De Pità, Girolomoni: Nitric oxide donors suppress chemokine production by keratinocytes in vitro and in vivo. in The American journal of pathology 2002 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal CXCL10 Primary Antibody for IA, IHC (fro) - ABIN2191897 : Curbishley, Eksteen, Gladue, Lalor, Adams: CXCR 3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow. in The American journal of pathology 2005 (PubMed)
    Show all 3 Pubmed References

  7. Human Polyclonal CXCL10 Primary Antibody for IF (p), IHC (p) - ABIN687442 : Li, Nishikawa, Kaneda: Platelet-cytokine Complex Suppresses Tumour Growth by Exploiting Intratumoural Thrombin-dependent Platelet Aggregation. in Scientific reports 2016 (PubMed)
    Show all 3 Pubmed References

  8. Human Monoclonal CXCL10 Primary Antibody for ELISA - ABIN2689797 : Luster, Ravetch: Biochemical characterization of a gamma interferon-inducible cytokine (IP-10). in The Journal of experimental medicine 1987 (PubMed)
    Show all 2 Pubmed References

  9. Rat (Rattus) Polyclonal CXCL10 Primary Antibody for ICC, IHC - ABIN1859462 : Han, Wang, Qin, Xia, Wu: LPS alters the immuno-phenotype of glioma and glioma stem-like cells and induces in vivo antitumor immunity via TLR4. in Journal of experimental & clinical cancer research : CR 2017 (PubMed)


Pig (Porcine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. a SNP in CXCL10 was significantly associated with percentage of lymphocyte in blood of 20-day-old pigs and with hematocrit and mean red cell volume in blood of 80-day-old pigs

  2. CXCL10 protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.

  3. Authors identified chemokine (C-X-C motif) ligand 10 (CXCL10), also named interferon-gamma inducible protein-10 (IP-10), as a novel target gene of miR-21.

  4. These in vitro and in vivo observations suggest that interferon-gamma inducible protein 10 (IP-10) may be a reliable biomarker for immune activity induced by CpG oligodeoxynucleotides in pigs.

  5. The swine CXCL10 gene contains four exons and three introns.

Human Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. TNFalpha by itself has no effect on the secretion of CXCL10, whereas it increases dose-dependently the secretion of CXCL8 in Graves' thyrocytes, and in Grave's opthalmopathy fibroblasts and preadipocytes, while IFNgamma does stimulate the secretion of CXCL10 but it inhibits that of CXCL8. This differential modulation of CXCL10 and CXCL8 chemokines may reflect a different role of the two chemokines in the course of the ...

  2. sCD163, CCL2, and CXCL10 are associated with activation of macrophages and may have a serious impact on overall survival in patients with idiopathic pulmonary fibrosis .

  3. Expression of CXCL10 was up-regulated in hepatocellular carcinoma (HCC) tissues, expression of CXCR3 was down-regulated in HBV-related HCC tissues

  4. results suggest that the CXCL10/CXCR3 axis may contribute to the pathogenesis of Behcet's disease

  5. Suggest that a novel and functionally interdependent interplay between EZH2 and G9a regulates histone methylation-mediated epigenetic repression of the antifibrotic CXCL10 gene in idiopathic pulmonary fibrosis.

  6. Studied role of chemokines (including C-X-C motif chemokine ligand 11 [CXCL11] and C-X-C motif chemokine ligand 10 [CXCL10] in the CXCR3 axis with regards to angiogenesis in adipose tissue of morbidly obese patients.

  7. CXCL10 blood level is associated with tuberculosis in the HIV infected patients.

  8. ur results showed that a fragment consisting of residues 196-413 in MERS-N is sufficient to up-regulate CXCL10, while the N-terminal domain and serine-arginine (SR)-rich motif of MERS-N do not play a role in this up-regulation.

  9. A strong correlation between elevated serum levels of IP-10 and DPPIV activity was seen in different cholestatic patient groups.

  10. The level of the serum IP-10 is higher in Chronic Hepatitis C patients compared to control group, and its level significantly decreased with effective antiviral treatment.

  11. hepatocellular carcinoma patients with a high concentration of CXCL10 in the tumor microenvironment had significantly poorer overall survival and disease-free survival than those with lower CXCL10 expression levels

  12. Inflammatory cytokines interleukin (IL)-1alpha, IL-1beta and interferon-gamma-induced protein (IP)-10 are biomarkers for detecting asymptomatic STIs and vaginal dysbiosis (bacterial vaginosis (BV) or intermediate microbiota).

  13. IP-10 is an alternative biomarker to IFN-gamma in the QFT-Plus format for the diagnosis of latent tuberculosis infection.

  14. Combination of IP-10 and RANTES could be potentially used as diagnostic and monitoring biomarker in pulmonary tuberculosis management.

  15. upregulated in synovium and chondrocytes following trauma

  16. The SNPs of CXCL9 (rs10336) and CXCL10 (rs3921) are not associated with the incidence of acute cellular rejection

  17. IP-10 is an accurate biomarker to screen febrile HIV-seronegative individuals.

  18. Elevated plasma level of CXCL10 is predictive of the active phase of tuberculosis infection.

  19. Results found that hepatitis A virus infection strongly induces the production of helper 1 T cell-associated chemokines, particularly CXCL10 via RIG-I-like receptor signaling, even without secreted interferons.

  20. Findings show that a combination of CRP, PCT, TRAIL and IP-10 can identify bacterial infections with higher accuracy than single biomarkers and combinations of a single bacterial biomarkers combined with TRAIL and IP-10.

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. Loss of CXCL10 is associated with Kidney Disease in Diabetes.

  2. This work highlights CXCL10 as a downstream effector of type I IFN signaling and suggests a division of labor in pDCs subtypes that likely impacts their function as effectors of viral responses and as drivers of inflammation.

  3. Study show that CXCL9 and CXCL10 are overexpressed in skin of HPV16 E7 transgenic mice when compared with non-transgenic animals. Immune cell infiltration to E7 transgenic skin is a consequence of epidermal hyperplasia, and that hyperplasia induces CXCL9 and CXCL10 production to recruit a subset of CXCR3+ T cells, promoting rejection of grafted E7 transgenic skin depleted of immunosuppressive lymphocytes.

  4. Forced expression of CXCL10 prevents in vitro growth and metastasis of colon carcinoma cells by recruiting natural killer cells.

  5. upregulated in synovium and chondrocytes following intra-articular fracture

  6. FNDC4 could suppress osteoclast formation via NF-kappaB pathway and downregulation of CXCL10

  7. This study explored the effect of CXCL10 on COPD induced by cigarette smoke (CS) and its underlying mechanism.

  8. CXCL10, not CXCL9 or CXCL11, induced IL-9 expression in the liver tissue.

  9. in vivo experiments show that the CXCL10/CXC chemokine receptor family 3 axis prevents the recruitment of macrophages, reduces inflammation, and halts the progression of the disease; the increased production of IL-1beta highlights the autoinflammatory nature of congenital hepatic fibrosis and may open novel therapeutic avenues

  10. CXCL10 and blood-brain barrier permeability enhancement in rabies virus infection

  11. Study shows that circulating interferon- that binds to receptors on brain endothelial cells and induces Cxcl10, is a central link in the signaling chain eliciting inflammation-induced aversion.

  12. The knockout of either CXCL10 or TNF-alpha reduced germ cell apoptosis in the co-cultures of germ cells and Sertoli cells in response to MuV infection. Local injection of MuV into the testes of mice confirmed the involvement of CXCL10 in germ cell apoptosis in vivo.

  13. CXCL10 has strong inhibitory effects on neovascularization, whereas MMP13 is required for neovascularization in C. albicans-infected corneas.

  14. Study provided the evidence that CXCL10/CXCR3 signaling in periaqueductal gray is involved in the development of morphine analgesic tolerance via neuron-microglia interaction.

  15. Results suggest that CXCL10(-/-) mice are protected against diet-induced nonalcoholic steatohepatitis (NASH), in an obesity-independent manner.

  16. In conclusion, upregulated CXCL10 in steatohepatitis impairs autophagic flux by reducing autolysosome formation, thereby inhibiting autophagic protein degradation and the accumulation of ubiquitinated proteins, leading to the development of steatohepatitis.

  17. These findings highlight the importance of CXCL10 signaling in the pathogenesis of rheumatoid arthritis and provide previously unidentified details of the mechanisms by which CXCL10 promotes the development of arthritis.

  18. Study revealed that CXCL10 evoked an ionic current mainly carried by Cl(-) channels, suggests that Cl(-) channels are likely key molecular candidates responsible for the CXCL10-evoked neuronal activation and itch-like behaviors in a murine model of allergic contact dermatitis induced by the antigen squaric acid dibutylester. Cl(-) channels may emerge as a promising drug target for the treatment of allergic itch.

  19. Collectively, these results suggest that the CXCL10/CXCR3-mediated NF-kappaB signaling pathway plays a role in the control of autonomous regulation of CXCL10 and malignant tumor properties in breast cancer 4T1 cells.

  20. results show an important role for CXCR3 and CXCL10 in the tissue distribution of preimmune memory phenotype CD8 T- cells

Cow (Bovine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. These results demonstrated that bovine colonic cells seem capable to respond to E. bovis merozoite I infection by the upregulation of CXCL10 and GM-CSF gene transcription.

  2. IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.

CXCL10 抗原简介


This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression.

Gene names and symbols associated with CXCL10

  • C-X-C motif chemokine ligand 10 (CXCL10) 抗体
  • C-X-C motif chemokine 10 (cxl10) 抗体
  • chemokine (C-X-C motif) ligand 10 (Cxcl10) 抗体
  • C-X-C motif chemokine ligand 10 (Cxcl10) 抗体
  • C7 抗体
  • CRG-2 抗体
  • CXCL10 抗体
  • gIP-10 抗体
  • Ifi10 抗体
  • INP10 抗体
  • IP-10 抗体
  • IP10 抗体
  • mob-1 抗体
  • Scyb10 抗体

Protein level used designations for CXCL10

chemokine (C-X-C motif) ligand 10 , C-X-C motif chemokine 10 , chemokine CXC-like protein , chemokine C-X-C motif ligand 10 , C-X-C motif chemokine 10-like protein , 10 kDa interferon gamma-induced protein , gamma IP10 , gamma-IP10 , interferon-inducible cytokine IP-10 , protein 10 from interferon (gamma)-induced cell line , small inducible cytokine subfamily B (Cys-X-Cys), member 10 , small-inducible cytokine B10 , interferon activated gene 10 , interferon-gamma induced protein CRG-2 , interferon-gamma-induced protein CRG-2 , small inducible cytokine B subfamily (Cys-X-Cys), member 10 , interferon-inducible protein 10 , protein Mob-1 , small inducible cytokine B subfamily (Cys-X-Cys) member 10 , gamma interferon inducible protein 10 , CXC chemokine ligand 10 , interferon-gamma-inducible protein 10 , interferon-gamma-inducible protein-10 , 10 kDa interferon-gamma-induced protein , 10 kDa interferon-gamma-inducible protein CXCL10 , IP-10 , small inducible cytokine B10

461242 Pan troglodytes
494019 Sus scrofa
100050993 Equus caballus
100195999 Salmo salar
3627 Homo sapiens
15945 Mus musculus
245920 Rattus norvegicus
615107 Bos taurus
478432 Canis lupus familiaris
442997 Ovis aries
574243 Macaca mulatta
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