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Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity). 再加上，我们可以发Chaperonin GroEL 蛋白 (3)和数多这个蛋白质的别的产品。
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The mechanism involved in the interaction of HSP60-Ass conjugate with HLA-DR-DRB allele considering the fact that Ass (1-42) is highly immunogenic in human and interactions evoked highly robust T-cell response through MHC class II binding predictions.
HSP60 (显示 HSPD1 抗体) showed pro-inflammatory properties in bronchial epithelial cells mediated by activation of TLR-4 (显示 TLR4 抗体)-related molecules.
HSP60 (显示 HSPD1 抗体) silencing deactivates the mTOR (显示 FRAP1 抗体) pathway to suppress glioblastoma progression
the effect of Hsp60 (显示 HSPD1 抗体) on differentiation and invasion of hepatocellular carcinoma cells might be associated with mitochondrial biogenesis
The results demonstrate that HSP60 (显示 HSPD1 抗体) participates in mitochondrial progesterone synthesis. These findings provide novel insights into progesterone synthesis in the human placenta and its role in maintaining pregnancy.
Clinical data showed that upregulation of miR (显示 MLXIP 抗体)-382/3-NT and downregulation of HSPD1 (显示 HSPD1 抗体)/Trx (显示 VAC14 抗体) were also observed in IgA (显示 IgA 抗体) nephropathy patients with renal interstitial fibrosis. These data supported a novel mechanism in which miR (显示 MLXIP 抗体)-382 targets HSPD1 (显示 HSPD1 抗体) and contributes to the redox imbalance in the development of renal fibrosis.
Low HSP60 (显示 HSPD1 抗体) expression is associated with beta-cell hypertrophy and dysfunction.
high level of ROS (显示 ROS1 抗体) is needed for tumorigenesis and progression in tumors with low HSP60 (显示 HSPD1 抗体) expression
HSP60 (显示 HSPD1 抗体) regulation of SOX9 (显示 SOX9 抗体) ubiquitination mitigates the development of knee osteoarthritis.
These findings shed some light on how a tumor cell may avert apoptosis using Hsp60 (显示 HSPD1 抗体) and point to the anti-cancer potential of drugs, such as CubipyOXA, which interfere with Hsp60 (显示 HSPD1 抗体)/pC3 (显示 PCSK1 抗体) complex formation, and thus allow the apoptotic cascade to proceed.
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
60 kDa chaperonin
, 60 kDa heat shock protein, mitochondrial
, P60 lymphocyte protein
, chaperonin 60
, heat shock protein 65
, mitochondrial matrix protein P1
, short heat shock protein 60 Hsp60s1
, chaperonin GroEL
, molecular chaperone GroEL