anti-Cell Death-Inducing DFFA-Like Effector C (CIDEC) 抗体

CIDEC encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. 再加上,我们可以发CIDEC 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CIDEC 63924 Q96AQ7
CIDEC 14311 P56198
CIDEC 500292  
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antibodies-online.cn销售最多的anti-CIDEC 抗体

Showing 10 out of 101 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
小鼠 非结合性 ELISA, FACS, ICC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 2:Western blot analysis using CIDEC mAb against human CIDEC (AA: 53-141) recombinant protein. (Expected MW is 36 kDa) Dilution: 1/500 - 1/2000 100 μL 8至11个工作日
$577.50
详细
非结合性 WB CIDEC Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35 µg/lane). This demonstrates the CIDEC antibody detected the CIDEC protein (arrow). 100 μL 2至3个工作日
$265.00
详细
非结合性 ICC, IHC, WB Figure. Western Blot; Sample: Human Hela Cells. 100 μg 13至16个工作日
$384.00
详细
非结合性 IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using CIDEC Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using CIDEC Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2至3个工作日
$302.50
详细
小鼠 非结合性 ELISA, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 2:Western blot analysis using CIDEC mAb against human CIDEC (AA: 53-141) recombinant protein. (Expected MW is 36 kDa) Dilution: 1/500 - 1/2000 100 μL 8至11个工作日
$577.50
详细
非结合性 ICC, IF, IHC, IHC (p), WB Anti-FSP27 / CIDEC antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml. 50 μL 11至14个工作日
$484.00
详细
非结合性 ELISA, WB Western blot analysis of CIDEC using HeLa whole cell lysates 100 μL 11至12个工作日
$390.77
详细
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat heart tissue labeled with Anti-CIDEC Polyclonal Antibody, Unconjugated (ABIN872596) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-NFAT4 Polyclonal Antibody, Unconjugated (ABIN872596) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3至7个工作日
$317.90
详细
非结合性 WB Western blot analysis in MDA-MB453 cell line lysates (35ug/lane). 400 μL 2至3个工作日
$515.63
详细
非结合性 ELISA, IF, IHC   100 μL Available
$363.46
详细

引用最多的anti-CIDEC 抗体

  1. Human Polyclonal CIDEC Primary Antibody for ICC, IF - ABIN151889 : Guillén, Navarro, Arnal, Noone, Arbonés-Mainar, Acín, Surra, Muniesa, Roche, Osada: Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver. in Physiological genomics 2009 (PubMed)
    Show all 7 Pubmed References

  2. Human Polyclonal CIDEC Primary Antibody for WB - ABIN528484 : Ito, Nagasawa, Omae, Ide, Akasaka, Murakami: Differential regulation of CIDEA and CIDEC expression by insulin via Akt1/2- and JNK2-dependent pathways in human adipocytes. in Journal of lipid research 2011 (PubMed)

  3. Human Monoclonal CIDEC Primary Antibody for ELISA, WB - ABIN528486 : Christensen, Nellemann, Jørgensen, Pedersen, Jessen: Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo. in Lipids in health and disease 2016 (PubMed)

  4. Human Polyclonal CIDEC Primary Antibody for ICC, IF - ABIN4298770 : Dabir, Kluge, McColl, Liu, Lam, Halmos, Wildey, Dowlati: PIAS3 activates the intrinsic apoptotic pathway in non-small cell lung cancer cells independent of p53 status. in International journal of cancer 2013 (PubMed)

更多抗CIDEC的相互作用对抗体

Cow (Bovine) Cell Death-Inducing DFFA-Like Effector C (CIDEC) interaction partners

  1. CIDEC may affect body measurement traits and meat quality traits in Qinchuan cattle, and could be used in marker-assisted selection.

  2. This paper examined the tissue expression profile of CIDEC gene in cattle.

Human Cell Death-Inducing DFFA-Like Effector C (CIDEC) interaction partners

  1. ApoA5 can inhibit the adipogenic differentiation of AMSC,and this effect may be mediated by down-regulating the expression of CIDEC. Furthermore, our results indicate that CIDEC could be considered as a key factor in adipogenic differentiation.

  2. FTO increased the lipid accumulation in hepatocytes by increasing nuclear translocation of SREBP1c and SREBP1c maturation, thus improving the transcriptional activity of lipid droplet-associated protein CIDEC.

  3. this study has indicated that 3' UTR variation in CIDEC is associated with the risk of elevated fasting glucose, the progression of hypertriglyceridemia and hypertension, and the efficacy of angiotensin II-targeted antihypertensive agents.

  4. Two tissue-specific CIDEc isoforms had different roles in lipid deposition.

  5. data suggested that Cidec could interact with and down-regulate AMPKalpha through an ubiquitin-proteasome degradation pathway, which provided a possible mechanism of Cidec in promoting human adipocytes differentiation

  6. Hepatic expression of FSP27/CIDEC is highly up-regulated in in patients with alcoholic steatohepatitis and this up-regulation contributes to alcohol-induced liver damage.

  7. It is insinuated that VAT is associated with late phase obesity CIDEC decrease and insulin resistance, while pioglitazone enhances CIDEC through activation of PPAR-gamma, increases its expression, and decreases lipolysis.

  8. After bariatric surgery-induced weight loss, CIDEC/FSP27 gene/protein expression in SAT increased significantly. Findings suggest a positive functional interaction between CIDEC/FSP27 & mitochondrial biogenesis-related genes in human adipose tissue

  9. Data indicate that fat-specific protein 27 (FSP27) increases the inhibitory effect of transcription factor Egr1 on the adipose triglyceride lipase (ATGL) promoter.

  10. results demonstrate a crucial role for FSP27-ATGL interactions in regulating lipolysis, triglyceride accumulation, and insulin signaling in human adipocytes

  11. homo-dimeric structure of the CIDE-N domain of FSP27 will provide important information that will enable better understanding of the function of FSP27.

  12. CIDE proteins expression correlate with tumor and survival characteristics in patients with renal cell carcinoma.

  13. Fsp27/CIDEC is a CREB target gene induced during early fasting in liver and regulated by FA oxidation rate.

  14. The results suggest that FSP27 not only modulates LD homeostasis but also modulates the response to osmotic stress via a physical interaction with NFAT5 at the LD surface.

  15. The expression of CIDE-3 was decreased in hepatocellular carcinoma (HCC) tissue, compared to adjacent normal tissues, and CIDE-3 expression and HCC differentiation were positively correlated.

  16. Results demonstrated that CIDEC-induced apoptosis was independent of FADD, suggesting that CIDEC-induced apoptosis might be in a death-receptor-independent, caspase-8-dependent manner.

  17. Insulin regulates CIDEA and CIDEC expression via PI3K, and it regulates expression of each protein via Akt1/2-and JNK2-dependent pathways, respectively, in human adipocytes.

  18. These results suggest that CIDEA and CIDEC are novel genes regulated by insulin in human adipocytes and may play key roles in the effects of insulin, such as anti-apoptosis and lipid droplet formation.

  19. Fat-specific protein 27 undergoes ubiquitin-dependent degradation regulated by triacylglycerol synthesis and lipid droplet formation

  20. Following gastric bypass the hepatic expression of CIDEC is downregulated by marked weight loss.

Mouse (Murine) Cell Death-Inducing DFFA-Like Effector C (CIDEC) interaction partners

  1. LXRalpha positively regulates Fsp27a and Fsp27b expression.

  2. a CIDEC domain that regulates LD fusion activity

  3. the role of gp78 and cidec in hepatic steatosis, were investigated.

  4. The current study demonstrated that insulin represses fasting-induced Fsp27 expression in the liver. The Fsp27 decreased by insulin is likely to cause the lower fat accumulation in liver.

  5. Fatty acids prevent CIDEC deacetylation by promoting the dissociation of CIDEC from HDAC6, resultin in increased association of CIDEC with PCAF on the endoplasmic reticulum.

  6. We show that partial silencing Fsp27 in either model results in the robust decrease in visceral fat, improved insulin sensitivity and whole-body glycemic control, and tissue-specific changes in transcripts controlling lipid oxidation and synthesis

  7. results suggest that FSP27beta negatively regulates CideA-promoted enlargement of lipid droplet size in brown adipocytes.

  8. Lipid droplet (LD) expansion depends on the FSP27 carboxy-terminal domain (amino acids 131-239). The negative charge of acidic residues D215, E218, E219 and E220 in the polar carboxy-terminal region (amino acids 202-239) is essential for LD enlargement.

  9. Data (including data from studies in knockout mice) suggest Cideb promotes lipid storage as droplets in hepatocytes under normal diet conditions; Cidea/Cidec promote fusion of lipid droplets leading to liver steatosis in fasting (16h) and obese mice.

  10. Cidea is highly associated with adiposity and insulin resistance, whereas Cidec is related to insulin sensitivity

  11. Hepatic expression of FSP27/CIDEC is highly up-regulated in mice following chronic-plus-binge ethanol feeding and this up-regulation contributes to alcohol-induced liver damage.

  12. Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice.

  13. CREBH-Fsp27beta axis is important for regulating lipid droplet dynamics and triglyceride storage in the liver

  14. Adipocyte-specific disruption of fat-specific protein 27 causes hepatosteatosis and insulin resistance in high-fat diet-fed mice.

  15. Promotion of FSP27 degradation may be an important factor responsible for the beneficial effect of AMPK activators on energy metabolism

  16. results demonstrate a crucial role for FSP27-ATGL interactions in regulating lipolysis, triglyceride accumulation, and insulin signaling in human adipocytes

  17. FSP27 mRNA expression in the liver depends on the etiology of fatty liver.

  18. Fsp27/CIDEC is a CREB target gene induced during early fasting in liver and regulated by FA oxidation rate.

  19. Perilipin1 (Plin1), another adipocyte-specific lipid droplet-associated protein, is an Fsp27 activator.

  20. FSP27 acts to constitutively limit the lipid droplet presence of ATGL, perilipin 1 plays an essential role in mediating the response of ATGL action to beta-adrenergic hormones.

Pig (Porcine) Cell Death-Inducing DFFA-Like Effector C (CIDEC) interaction partners

  1. CIDEC protects lipid droplets (LDs) by decreasing the specific surface area of LDs and is involved in the regulation of hepatic lipid deposition.

  2. CIDEa and CIDEc mRNA level in white adipose tissues and liver were significantly higher in obese pigs than in their lean counterparts

CIDEC 抗原简介

蛋白简介

This gene encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis. This gene is regulated by insulin and its expression is positively correlated with insulin sensitivity. Mutations in this gene may contribute to insulin resistant diabetes. A pseudogene of this gene is located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.

Gene names and symbols associated with CIDEC

  • cell death inducing DFFA like effector c (cidec) 抗体
  • cell death inducing DFFA like effector c S homeolog (cidec.S) 抗体
  • cell death inducing DFFA like effector c (CIDEC) 抗体
  • cell death-inducing DFFA-like effector c (cidec) 抗体
  • Cell death activator CIDE-3 (cidec) 抗体
  • cell death-inducing DFFA-like effector c (Cidec) 抗体
  • CIDE-3 抗体
  • CIDE-C 抗体
  • CIDE3 抗体
  • CIDEC 抗体
  • fd36c01 抗体
  • FPLD5 抗体
  • Fsp27 抗体
  • MGC82483 抗体
  • MGC89274 抗体
  • wu:fd36c01 抗体
  • zgc:153033 抗体

Protein level used designations for CIDEC

cell death-inducing DFFA-like effector c , cell death activator CIDE-3 , cell death-inducing DFFA-like effector protein C , fat-specific protein FSP27 homolog , Cell death activator CIDE-3 , fat specific protein 27 , CIDE-3alpha , fat specific gene 27 , fat-specific protein FSP27 , cell-death-inducing DNA-fragmentation-factor-like effector C

GENE ID SPECIES
493464 Xenopus (Silurana) tropicalis
446635 Xenopus laevis
460156 Pan troglodytes
484662 Canis lupus familiaris
534607 Bos taurus
564304 Danio rerio
703021 Macaca mulatta
100196180 Salmo salar
63924 Homo sapiens
14311 Mus musculus
100127161 Sus scrofa
500292 Rattus norvegicus
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