anti-Cartilage Acidic Protein 1 (CRTAC1) 抗体

CRTAC1 encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. 再加上,我们可以发Cartilage Acidic Protein 1 试剂盒 (11)Cartilage Acidic Protein 1 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CRTAC1 55118 Q9NQ79
CRTAC1 72832 Q8R555
CRTAC1 171438  
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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-CRTAC1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: HepG2 cell lysate 100 μL Log in to see 2至3个工作日
非结合性 IHC, IHC (p), WB Immunohistochemistry: CRTAC1 Antibody [NBP1-88864] - Staining of human heart muscle shows strong cytoplasmic positivity in dot like pattern in myocytes. Western Blot: CRTAC1 Antibody [NBP1-88864] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 1o. Lane 2: Human lung tissue. 0.1 mL Log in to see 10至13个工作日
非结合性 WB CRTAC1 Antibody (N-term)  western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the CRTAC1 antibody detected the CRTAC1 protein (arrow). 400 μL Log in to see 10至11个工作日
小鸡 非结合性 WB 50 μg Log in to see 11至14个工作日
非结合性 WB Western Blot: CRTAC1 Antibody [NBP1-57722] - HepG2 cell lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8至11个工作日
非结合性 WB Western blot analysis of extracts of NCI-H292 cells, using CRTAC1 antibody (ABIN4903382). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. 100 μL Log in to see 16 Days
小鼠 非结合性 WB Western Blot analysis of CRTAC1 expression in transfected 293T cell line by CRTAC1 MaxPab polyclonal antibody.Lane 1: CRTAC1 transfected lysate(49.61 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 11至12个工作日
非结合性 ELISA, WB   200 μL Log in to see 11至16个工作日
Alexa Fluor 350 IF (p)   100 μL Log in to see 14至21个工作日
Cy5 IF (p)   100 μL Log in to see 14至21个工作日

更多抗Cartilage Acidic Protein 1的相互作用对抗体

Human Cartilage Acidic Protein 1 (CRTAC1) interaction partners

  1. Confirm the increase of CRTAC1 in cartilage biopsies from OA patients undergoing joint replacement by real-time PCR and immunohistochemistry. Furthermore, we report that proinflammatory cytokines interleukin-1beta and tumor necrosis factor alpha upregulate CRTAC1 expression in primary articular chondrocytes and synovial fibroblasts.

  2. It was shown for the first time the propensity of CRTAC1 to form amyloid-like structures, and it was hypothesized that the aggregating property of CRTAC1 may be related to its disease-association.

  3. These results provided new insights into the mechanism of cataract development, and demonstrated that CRTAC1 could be a potentially novel target for cataract treatment.

  4. CRTAC1 acquired an alternate last exon from the tail-to-tail oriented neighbouring gene in humans resulting in the glycosylated isoform CRTAC1-A which represents a new extracellular matrix molecule of articular cartilage.

  5. in bone fracture patients, 12 proteins were related to bone/cartilage metabolism, including: TGF-beta induced protein IG-H(3), cartilage acidic protein 1, procollagen C proteinase enhancer protein and TGF-beta receptor III.

Mouse (Murine) Cartilage Acidic Protein 1 (CRTAC1) interaction partners

  1. Genetic deletion of Crtac1 significantly inhibited cartilage degradation, osteophyte formation and gait abnormalities of post-traumatic OA in female, but not male, animals undergoing the destabilization of medial meniscus (DMM) surgery.

  2. These data suggest that LOTUS functions as a potent endogenous antagonist for NgR1 when bound by all four known NgR1 ligands.

  3. These findings suggest that the UA/EC region is a functional domain of LOTUS serving for an antagonistic action to NgR1.

  4. found CRTAC1-B(LOTUS)is key molecule for lateral olfactory tract(LOT)formation; NgR1 is LOTUS-binding protein;LOTUS suppressed Nogo-NgR1 binding and Nogo-induced growth cone collapse;suggest endogenous antagonism of NgR1 by LOTUS crucial for LOT formation

Cartilage Acidic Protein 1 (CRTAC1) 抗原简介


This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with CRTAC1

  • cartilage acidic protein 1 (CRTAC1) 抗体
  • cartilage acidic protein 1a (crtac1a) 抗体
  • cartilage acidic protein 1 (crtac1) 抗体
  • cartilage acidic protein 1 (aspip) 抗体
  • cartilage acidic protein 1 (Crtac1) 抗体
  • 2810454P21Rik 抗体
  • ASPIC 抗体
  • ASPIC1 抗体
  • ASPIP 抗体
  • AW047536 抗体
  • cb184 抗体
  • CEP-68 抗体
  • crtac1 抗体
  • Crtac1B 抗体
  • Lotus 抗体
  • MGC146658 抗体
  • sb:cb184 抗体
  • W307 抗体
  • zgc:165343 抗体

Protein level used designations for CRTAC1

cartilage acidic protein 1 , ASPIC , cartilage acidic protein 1a , acidic secreted protein in cartilage , chondrocyte expressed protein 68 kDa CEP-68 , 68 kDa chondrocyte-expressed protein , CEP-68 , protein CRTAC1-B

425346 Gallus gallus
450660 Pan troglodytes
559626 Danio rerio
707486 Macaca mulatta
779826 Xenopus (Silurana) tropicalis
100021408 Monodelphis domestica
100060874 Equus caballus
100125469 Oryzias latipes
100352703 Oryctolagus cuniculus
100476456 Ailuropoda melanoleuca
100593381 Nomascus leucogenys
55118 Homo sapiens
72832 Mus musculus
608827 Canis lupus familiaris
100139581 Bos taurus
171438 Rattus norvegicus
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