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Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. 再加上，我们可以发Carbonic Anhydrase VB, Mitochondrial 试剂盒 (21) 和 Carbonic Anhydrase VB, Mitochondrial 蛋白 (15)和数多这个蛋白质的别的产品。
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Human Polyclonal CA5B Primary Antibody for ELISA, WB - ABIN564889
Pan, Waheed, Sly, Parkkila: Carbonic anhydrases in the mouse harderian gland. in Journal of molecular histology 2010
In 10 of 96 patients, mutations in CA5A (显示 CA5A 抗体) were identified on both alleles but none in CA5B. Exhibiting decreased enzyme activity or thermal stability, all CAVA (显示 CA5A 抗体) mutations were proven to cause disease, whereas the three variants showed no relevant effect
activators enhanced kcat, with no effect on KM, favoring the RDS (显示 PRPH2 抗体) in the catalytic cycle; the activation pattern of the two mitochondrial isoforms is very different from each other and as compared to those of the cytosolic isoforms hCA I and II.
both Car5A (显示 CA5A 抗体) and Car5B contribute to both ammonia detoxification (ureagenesis) and regulation of fasting blood sugar (gluconeogenesis).
Car5b and Car13 (显示 CA13 抗体) showed the highest signals in the mouse harderian gland.
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles.
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