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CA2 is one of several (at least 7) isozymes of carbonic anhydrase. 再加上，我们可以发Carbonic Anhydrase II 试剂盒 (64) 和 Carbonic Anhydrase II 蛋白 (49)和数多这个蛋白质的别的产品。
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Human Polyclonal CA2 Primary Antibody for ID, IF - ABIN2477889
Uggeri, Proctor, Johns: Halothane, enflurane, and isoflurane attenuate both receptor- and non-receptor-mediated EDRF production in rat thoracic aorta. in Anesthesiology 1992
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Human Polyclonal CA2 Primary Antibody for WB - ABIN1882068
Fisher, Kovalevsky, Domsic, Mustyakimov, Silverman, McKenna, Langan: Preliminary joint neutron and X-ray crystallographic study of human carbonic anhydrase II. in Acta crystallographica. Section F, Structural biology and crystallization communications 2009
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a bicarbonate transport metabolon proposed for the interaction between CAII and NBCe1 (显示 SLC4A4 抗体) does not work at least in Xenopus oocytes
CA2 is an integral membrane protein localized on the matrix-exposed side of the membrane arm of complex I.
It was concluded that both MCT1 (显示 MCTS1 抗体) and CAII are involved in the homeostatic control of pH in skeletal muscle, both at rest and at the onset of exercise. The improved muscle function and resistance to fatigue in MCT1 (显示 MCTS1 抗体)(+/-) mice remain unexplained.
two CA isoforms, CAII and CAIV (显示 CA4 抗体), are distributed along the epididymal epithelium and appear with the onset of puberty
The Na(+)-Cl(-) cotransporter NCC (显示 SLC12A3 抗体) /Carbonic anhydrase II double Knockout mice displayed significant downregulation of pendrin (显示 SLC26A4 抗体), along with polyuria and salt wasting.
CA2 expression is strongly regulated by intracellular pH and by cAMP, suggesting a role for soluble adenylyl cyclase (显示 ADCY10 抗体)
sclerostin (显示 SOST 抗体) upregulated osteocyte expression of carbonic anhydrase 2.
During inner ear development, transcripts of four cytosolic isozymes (Car1 (显示 CA1 抗体), Car2, Car3 (显示 CA3 抗体), and Car13 (显示 CA13 抗体)), two membrane-bound isozymes (Car12 and Car14 (显示 CA14 抗体)), and two CA-related proteins (Car8 (显示 CA8 抗体) and Car11 (显示 CA11 抗体)) were expressed at higher levels than other isozymes.
Car2, Car3, Car7, and Car15 mRNAs were barely within the detection limits in the mouse harderian gland.
Suggest that during amelogenesis CAII controls the differentiation of ameloblasts. Regulation of intracellular pH, followed by activation of the JNK (显示 MAPK8 抗体) signaling pathway, may be responsible for the effects of CAII on ameloblasts.
Both kNBC1 (显示 SLC4A4 抗体)-Asp (显示 C3 抗体)(986) and kNBC1 (显示 SLC4A4 抗体)-Asp (显示 C3 抗体)(988), but not kNBC1 (显示 SLC4A4 抗体)-Asp (显示 C3 抗体)(989), are required for the phosphorylation-induced shift in stoichiometry. A homologous motif (D887ADD) in the carboxy-terminus of the anion exchanger AE1 (显示 SLC4A1 抗体) binds to carbonic anhydrase II.
Results show that the stimulatory effect of the duodenal secretagogue prostaglandin E2 completely depends on carbonic anhydrase II.
These six-membered carbocycles showed nice inhibitory action against AChE and human carbonic anhydrase (hCA) II and I isoforms. The hCA I, II, and AChE were efficiently inhibited by these molecules, with Ki values in the range of 6.70-35.85 nM for hCA I, 18.77-60.84 nM for hCA II, and 0.74-4.60 for AChE, respectively
Discovery of potent carbonic anhydrase, acetylcholinesterase (显示 AChE 抗体), and butyrylcholinesterase (显示 BCHE 抗体) enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base.
This study provides the first evidence that extra-platelet nitrite and erythrocytic CAII may modulate platelet function in a cGMP-dependent manner.
Here are presented solved the first crystal structures of carbonic anhydrase 1and carbonic anhydrase 2 in complex with polmacoxib, at 2.0 A and 1.8 A, respectively.
CA II and CA XII, but not CA VII (显示 CA7 抗体) or CA IX (显示 CA9 抗体), could be useful in predicting survival in colorectal carcinomas
This article presents different classes of structures of the mutant His-107-Tyr (显示 TYR 抗体) of human CA-II by harvesting molecular dynamics trajectories at low and high temperatures. Identified are putative unfolding intermediates of the mutant His-107-tyr (显示 TYR 抗体) of human carbonic anhydrase II in a multidimensional property space.
The levels of expression of carbonic anhydrase 2, catalase (显示 CAT 抗体), and PRDX2 (显示 PRDX2 抗体) in the nipple discharge were significantly increased in breast ductal carcinoma patients as compared to controls.
This study suggests that the expression of CA II acts as independent prognostic biomarker for survival in pseudomyxoma peritonei
identified 2 novel mutations in 2 Chinese families with CAII deficiency syndrome; a nonsense mutation in exon 4 in both families; a splice mutation at the splice donor site of intron 3 in 1 family; the splice-site mutation causes exon 3 skipping in patient's mRNA resulting in an in-frame deletion and a novel premature stop codon
binding of dorzolamide to bovine and human carbonic anhydrase II
Increasing the number and distribution of surface acidic groups of CAII is sufficient to function in high-salt environments.
Folding analysis of the zinc protein, carbonic anhydrase 2 was performed using electrospray ionization ion mobility spectrometry coupled with collision-induced dissociation.
Intense positive staining for CA-II was found in luminal duct cells and for the first time also inside the duct lumen, clearly demonstrating the expression and secretion of salivary CA-II in bovine parotid glands.
structure refined to 1.95 A resolution; has a C-terminal knot (显示 KCNK7 抗体) structure; contains one zinc ion in the active site coordinated to 3 his and 1 water molecule; structure reveals a probable alternative proton-wire pathway that differs from that of HCA II.
novel series of mono- and bis (显示 BAG3 抗体)- benzene sulfonamides with potent binding affinity for bovine carbonic anhydrase II
catalytic activity of CAII affects the SNAT3 (显示 SLC38A3 抗体) conductance, but presumably not by increasing the local H+ buffer capacity
kinetics of refolding of carbonic anhydrase II following transfer from a buffer containing 5 m guanidinium chloride to a buffer containing 0.5 m guanidinium chloride
The urea-induced unfolding of bovine carbonic anhydrase II, BCA (显示 BLNK 抗体) II, is characterized by a combination of high-resolution NMR, circular dichroism spectroscopy and small angle X-ray scattering.
CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis.
, carbonic anhydrase 2
, carbonic anhydrase II
, carbonic anhydrase type 2
, erythrocyte carbonic anhydrase
, CA II
, carbonate dehydratase II
, carbonic anhydrase B
, carbonic anhydrase C
, carbonic dehydratase