Calsyntenin 1 (CLSTN1) ELISA试剂盒

Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. 再加上,我们可以发Calsyntenin 1 抗体 (69)Calsyntenin 1 蛋白 (14)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
小鼠 CLSTN1 CLSTN1 65945 Q9EPL2
CLSTN1 22883 O94985
大鼠 CLSTN1 CLSTN1 313717 Q6Q0N0
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产品编号 适用 灵敏度 范围 图像 规格 交付 价格 详细
0.094 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests 12至14个工作日
$630.00
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适于 Calsyntenin 1 相互作用对的更多 ELISA 试剂盒

Zebrafish Calsyntenin 1 (CLSTN1) interaction partners

  1. Our results suggest a model in which Clstn-1 patterns separate axonal compartments and define their ability to branch by directing trafficking of specific endosomes.

Mouse (Murine) Calsyntenin 1 (CLSTN1) interaction partners

  1. These results indicate that regulated intramembrane proteolysis of Alca by gamma-secretase regulates APP trafficking and the production of Abeta in vivo.

  2. these results highlight a key role for calsyntenin-1 in the transport of NMDA receptors to synaptic targets, which is necessary for the maturation of neuronal circuits during early development.

  3. Alcalpha is efficiently processed in part to minimize the inappropriate peripheral retention of kinesin-1

  4. Immunoisolated calsyntenin-1 organelles from murine brain homogenates; determined their proteome by MS. Found calsyntenin-1 organelles are endowed with components of the endosomal trafficking machinery and contained the beta-amyloid precursor protein (APP).

  5. Phosphorylation of KLC1 at serine 460 modulates binding and trafficking of calsyntenin-1.

  6. Calsyntenin-1 links a certain type of vesicular and tubulovesicular organelles to the Kinesin-1 motor.

  7. The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport.

Human Calsyntenin 1 (CLSTN1) interaction partners

  1. Results suggests that APP partially compensates for defective Alcalpha in anterograde transport by providing an alternative cargo receptor for kinesin-1.

  2. Calsyntenin-1 contributes to the early stages of the hepatitis C virus replication cycle and the formation of the replication complex.

  3. Increased plasma p3-Alcalpha35, a major fragment of alcalpha1, may indicate an endophenotype in Alzheimer's disease patients with progressive cognitive impairment.

  4. Increased plasma p3-alcadein (alc) alpha, evident in the early stages of cognitive impairment, suggests that alc metabolites are useful plasma biomarkers of Alzheimer's disease.

  5. findings show that calsyntenin-1 is reduced in Alzheimer's disease brains and that the extent of this reduction correlates with increased amyloid-beta

  6. CLSTN1 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells.

  7. Phosphorylation of KLC1 at serine 460 modulates binding and trafficking of calsyntenin-1.

  8. Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation [alcalpha1, alcbeta, alcgamma]

Calsyntenin 1 (CLSTN1) 抗原简介

Antigen Summary

Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2- mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1- binding. May modulate calcium-mediated postsynaptic signals (By similarity).

Gene names and symbols associated with Calsyntenin 1 (CLSTN1) ELISA试剂盒

  • calsyntenin 1 (CLSTN1) 抗体
  • calsyntenin 1 (clstn1) 抗体
  • calsyntenin 3 (clstn3) 抗体
  • beta-catenin-interacting protein 1 (LOC100356725) 抗体
  • calsyntenin-1 (LOC100435584) 抗体
  • calsyntenin 1 (Clstn1) 抗体
  • beta-catenin-interacting protein 1 (LOC479600) 抗体
  • 1810034E21Rik 抗体
  • ALC-ALPHA 抗体
  • alcalpha1 抗体
  • alcalpha2 抗体
  • CALSYNTENIN-1 抗体
  • CDHR12 抗体
  • clstn1 抗体
  • Cst-1 抗体
  • CSTN1 抗体
  • fm67g03 抗体
  • PIK3CD 抗体
  • wu:fk52g02 抗体
  • wu:fm67g03 抗体
  • XB31alpha 抗体
  • zgc:56528 抗体
  • zgc:153744 抗体

Protein level used designations for Calsyntenin 1 (CLSTN1) ELISA试剂盒

calsyntenin-1 , calsyntenin 1 , calsyntenin 3 , calsyntenin-1-like , alc-alpha , alcadein alpha , alcadein-alpha , alcadein alpha 1 , alzheimer-related cadherin-like protein , cadherin-related family member 12 , non-classical cadherin XB31alpha , non-classical cadherin XB31alpha1

GENE ID SPECIES
395372 Gallus gallus
722304 Macaca mulatta
777737 Danio rerio
100145668 Xenopus (Silurana) tropicalis
100356725 Oryctolagus cuniculus
100435584 Pongo abelii
100611252 Pan troglodytes
65945 Mus musculus
22883 Homo sapiens
313717 Rattus norvegicus
479600 Canis lupus familiaris
100520617 Sus scrofa
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