CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) ELISA试剂盒

CTDSP1 encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. 再加上,我们可以发CTDSP1 抗体 (111)CTDSP1 蛋白 (7)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
大鼠 CTDSP1 CTDSP1 363249  
CTDSP1 58190 Q9GZU7
CTDSP1 227292 P58466
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适于 CTDSP1 相互作用对的更多 ELISA 试剂盒

Human CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) interaction partners

  1. REST is a bona fide substrate for SCP1 in vivo and that SCP1 phosphatase activity protects REST against degradation.

  2. Our results provide a novel mechanistic insight into the activation of Myc by 27-HC via transcriptional repression of PP2A, SCP1 and FBW7 to increase Myc protein stability in breast cancer cells.

  3. SCP1 is the phosphatase that counterregulates the MAPK-mediated phosphorylation of Ser(68)-Twist1.

  4. SCP1 regulates c-Myc stability and functions through dephosphorylating c-Myc Serine-62.

  5. hSCP1 may be an beta-O-linked N-acetylglucosamine modified protein in vivo.

  6. CTDSP1 activity stabilizes REST in stem cells and ERK-dependent phosphorylation combined with Pin1 activity promotes REST degradation in neural progenitors.

  7. SCP1 phosphatase substrate specificity: CdcA3 could be an enzymatic substrate for SCP1.

  8. Captured the phosphoryl-aspartate intermediate in the crystal structure of a Scp1D206A mutant soaked with para-nitrophenyl phosphate (pNPP), providing strong evidence for the proposed mechanism.

  9. Polymorphisms vary significantly between races; Not associated with TB susceptibility in Caucasians.

  10. SCP1 may play a role in the regulation of gene expression, possibly by controlling the transition from initiation/capping to processive transcript elongation

  11. results show that REST/NRSF recruits SCPs to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells

  12. SCP1 acts as a phosphatase for regulatory phosphorylations in the linker region of Smad1 and Smad2.

Mouse (Murine) CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) interaction partners

  1. Consistently, the authors observed increased AKT phosphorylation and angiogenesis followed by enhanced tumorigenesis in Ctdsp1 (which encodes SCP1) gene - knockout mice. Importantly, they discovered that the membrane localization of SCP1 is crucial for impeding angiogenesis and tumor growth, and this localization depends on palmitoylation of a conserved cysteine motif within its NH2 terminus.

  2. Golli-BG21 enhanced SCP1/GIP phosphatase activity, whereas PKCalpha-phosphorylated BG21 inhibited its activity, suggesting a potential role of BG21 as a molecular switch ("quick-brake mechanism") on SCP1/GIP.

  3. Findings suggest that SCP1 may inhibit the osteoblastic differentiation induced by the BMP-Smad axis via Runx2 by suppressing downstream effector(s).

  4. Expression and purification of the active variant of recombinant murine Golli-interacting protein (GIP) and its characterization

CTDSP1 抗原简介

Antigen Summary

This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with CTDSP1

  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (CTDSP1) 抗体
  • CTD small phosphatase 1 (CTDSP1) 抗体
  • CTD small phosphatase 1 (Ctdsp1) 抗体
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (ctdsp1) 抗体
  • carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (HCAG_04820) 抗体
  • carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTRG_06220) 抗体
  • CTD small phosphatase 1 (ctdsp1) 抗体
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (Ctdsp1) 抗体
  • CTDSP1 抗体
  • fj83f12 抗体
  • GIP 抗体
  • im:7141428 抗体
  • Nif3 抗体
  • NLI-IF 抗体
  • NLIIF 抗体
  • SCP1 抗体
  • wu:fj83f12 抗体
  • zgc:113169 抗体

Protein level used designations for CTDSP1

carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 , CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 , NLI-interacting factor 3 , nuclear LIM interactor-interacting factor 3 , small C-terminal domain phosphatase 1 , golli-interacting protein , small CTD phosphatase 1

GENE ID SPECIES
608466 Canis lupus familiaris
516199 Bos taurus
459943 Pan troglodytes
363249 Rattus norvegicus
58190 Homo sapiens
553744 Danio rerio
5447218 Ajellomyces capsulatus NAm1
8301559 Candida tropicalis MYA-3404
100350904 Oryctolagus cuniculus
100380164 Xenopus (Silurana) tropicalis
227292 Mus musculus
100726065 Cavia porcellus
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