CD68 Molecule (CD68) ELISA试剂盒

CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. 再加上,我们可以发CD68 抗体 (559)CD68 蛋白 (29)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
CD68 12514 P31996
CD68 287435  
CD68 968 P34810
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小鼠 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 15至18个工作日
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3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 13至16个工作日
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大鼠 0.156 ng/mL 0.625-40 ng/mL Typical standard curve 96 Tests Log in to see 13至16个工作日
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引用最多的CD68 ELISA试剂盒

  1. Rat (Rattus) CD68 ELISA Kit for Sandwich ELISA - ABIN457212 : Schlegel, Graf, Clavien, Dutkowski: Hypothermic oxygenated perfusion (HOPE) protects from biliary injury in a rodent model of DCD liver transplantation. in Journal of hepatology 2013 (PubMed)

适于 CD68 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) CD68 Molecule (CD68) interaction partners

  1. Scavenger receptor CD68 antigen plays a role in chronic liver injury, which has implications for the design of anti-fibrotic therapies.

  2. Findings indicate that human CD68 and its mouse ortholog macrosialin located in the lysosomal membrane and share many structural similarities.

  3. Myeloid osteoclast precursors do not express CD68.

  4. CD68, a putative receptor for sporozoite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver.

  5. Results showed that activated microglia in Alzheimer's disease-like mice showed two-step transition: a CD68-negative activated form at 6-9 months and a CD68-positive form from 12 months of age

  6. Statins promote the beneficial remodeling of plaques in diseased mouse arteries through the stimulation of the CCR7 / CD68 emigration pathway in macrophages

  7. These findings demonstrate a role for CD68 in the function of osteoclasts.

  8. CD68-null mononuclear phagocytes exhibited a trend toward enhanced antigen presentation to CD4+ T cells, indicating that CD68 may function to negatively regulate antigen uptake, loading, or major histocompatibility complex class II trafficking.

  9. Atherogenic diet-induced reduction in lipid levels of Reversa model mouse leads to decreased monocyte-derived CD68-positive cells in advanced atherosclerotic plaques and is associated with emigration of these cells from the atherosclerotic plaques.

  10. Macrosialin does not function as an oxLDL receptor on the cell surface.

  11. Data show that macrosialin (CD68), a macrophage-specific protein, is increased by aging in selected brain regions of male C57BL/6NNia mice.

Human CD68 Molecule (CD68) interaction partners

  1. Study of the in-situ expression and significance of tumor-associated macrophages biomarkers (CD68, CD163, and MMP-9) in breast cancer with different estrogen receptor (ER) status revealed that high pan-macrophage marker CD68 correlated with poorer overall survival only in ER- breast cancer.

  2. CD68 seems to play a role in the oxLDL metabolism in the vessel wall at early stages of atherosclerosis.

  3. CD68(+) and/or CD163(+) tumor-associated macrophage infiltration as well as CLSs are present in adipose tissue nearby the breast cancer lesion, and are associated with various clinicopathologic parameters of breast cancer.

  4. Combined detection of tumor-associated macrophages markers, CD68 and Sema4D, in gastric carcinoma tissue shows potential to predict the trend of gastric carcinoma progression.

  5. The study revealed that CD16-CD68-expressing macrophages appear to participate in ureteral neoplastic transformation.

  6. A combination of CD68/CD206 density and HBV-positivity improves further predictive value for post-operative recurrence of hepatocellular carcinoma (HCC) . Quantification of CD68/CD206 macrophages and their distribution can be exploited for better postsurgical management of HCC patients.

  7. Report CD68 over-expression in multinucleated giant cells and mononuclear cells in central and peripheral giant cell granuloma of jaw.

  8. This study shown the CD68 expression in Microglia and Astrocytes in stroke, Alzheimer's disease, and Lewy body dementia.

  9. The results of this study found that the expression levels of Cd68 and Atp5b were significantly correlated with the neurofibrillary tangle burden in the Alzheimer's Disease brain and with their cognition.

  10. Taken together, these results suggested that the changes, including ox-LDL/LDL ratio, CD68(+)/RANK(+) cells number, and the levels of RANKL and HMGB1 in AS patients, favored osteoclastogenesis.

  11. High expression of CD68 is associated with nonalcoholic steatohepatitis.

  12. increased amount of CD68+TAM in gaps of ductal tumor structures is protective against metastatic spread in regional lymph nodes.

  13. Most cases of histiocytic sarcoma expressed histiocytic markers CD68 (6 of 7 cases), CD163 (5 of 5 cases), and PU.1 (3 of 4 cases).

  14. Renal expression of CD68 and the chronicity index are associated with progression to chronic kidney disease in patients with proliferative lupus nephritis.

  15. Results indicate that the expression of FoxP3 was not significantly associated with survival, and suggest prognostic significance of high CD68 expression in primary central nervous system lymphoma (PCNSL).

  16. Her-2 overexpression results in ICA were similar to previous reports, the finding of 28% in HGD was unexpected and may have clinical implications. Positive Her-2 DISH in 6% of LGD is novel, suggesting a role of Her-2 during BE progression

  17. CD68 may play key roles in the pathogenesis of Alzheimer's disease (AD) and its complications may be via induction of inflammation; CD68 may be considered as a risk factor for development of AD and also psychotic symptoms in the patients

  18. hCD68GFP/ApoE(-/-) mice provide a new approach to study macrophage accumulation in atherosclerotic plaque progression and to identify cells recruited from adoptively transferred monocytes.

  19. Findings indicate that human CD68 and its mouse ortholog macrosialin located in the lysosomal membrane and share many structural similarities.

  20. The strong CD68 and S100 co-expression in our case did not allow a clear-cut discrimination between the immunophenotype of histiocytic neoplasms and amelanotic melanoma, because of CD68 immunoreactivity occurring in 75% of metastatic malignant melanomas

CD68 抗原简介

Antigen Summary

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Gene names and symbols associated with CD68 Molecule (CD68) ELISA试剂盒

  • CD68 molecule (CD68) 抗体
  • CD68 antigen (Cd68) 抗体
  • Cd68 molecule (Cd68) 抗体
  • GP110 抗体
  • LAMP4 抗体
  • SCARD1 抗体

Protein level used designations for CD68 Molecule (CD68) ELISA试剂盒

macrosialin , CD68 antigen , macrophage antigen CD68 , scavenger receptor class D, member 1

GENE ID SPECIES
100344094 Oryctolagus cuniculus
12514 Mus musculus
287435 Rattus norvegicus
968 Homo sapiens
504960 Bos taurus
101099002 Felis catus
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