C-Type Lectin Domain Family 10, Member A (CLEC10A) ELISA试剂盒

CLEC10A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. 再加上,我们可以发CLEC10A 抗体 (140)CLEC10A 蛋白 (23)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
CLEC10A 10462 Q8IUN9
CLEC10A 17312 P49300
大鼠 CLEC10A CLEC10A 64195  
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Human C-Type Lectin Domain Family 10, Member A (CLEC10A) interaction partners

  1. this paper shows that key gene of intermediate proinflammatory monocytes, such as CLEC10A, is expressed three- to fourfold more in juvenile idiopathic arthritis-enthesitis-related arthritis

  2. BRAF(V600E) mutation induces MGL ligand expression, thereby providing a direct link between oncogenic transformation and aberrant expression of immunosuppressive glycans in colorectal neoplasms.

  3. These results indicate a role of MGL as an immunomodulator within the tumour microenvironment interfering with Treg functions, suggesting its possible use in the design of anticancer vaccines.

  4. expression of GalNAc moieties mirrors the T cell activation status, and thus only highly stimulated T cells are prone to the suppressive action of MGL.

  5. MGL triggering synergized with TLR2-induced pathways, leading to elevated IL-10 mRNA levels & enhanced TNF-alpha mRNA stability. It promoted phosphorylation of the ERK & CREB, fine-tuning the DC maturation phenotype.

  6. Described is the use of recombinant CLEC10A (CD301), a human glycoreceptor of the C-type lectin family, for the detection of ligands in sections from formalin-fixed, paraffin-embedded normal and cancerous mammary tissues.

  7. MGL engagement improved DC performance as antigen-presenting cells, promoting the upregulation of maturation markers, a decrease in phagocytosis, an enhancement of motility, and most importantly an increase in antigen-specific CD8(+) T-cell activation.

Mouse (Murine) C-Type Lectin Domain Family 10, Member A (CLEC10A) interaction partners

  1. Loss of Mgl1 expression is associated with enhanced alpha2-3Neu-von Willebrand factor clearance.

  2. Macrophage Galactose-Type Lectin-1 Deficiency Is Associated with Increased Neutrophilia and Hyperinflammation in Gram-Negative Pneumonia

  3. Mgl1-deficient mice displayed accelerated colonic propulsion and were hypersensitive to mu receptor-mediated inhibition of colonic motility.

  4. MGL1 is involved in T. crassiceps recognition and subsequent innate immune activation and resistance.

  5. The MGL1 functions as an attachment and entry receptor for influenza A virus.

  6. Syk was involved in the CLR-mediated activation of mast cells by BP

  7. Hoxc8 downregulates Mgl1 tumor suppressor gene expression and reduces its concomitant function on cell adhesion.

  8. The authors conclude that lectin-mediated interactions of influenza virus with the MMR or the MGL are required for the endocytic uptake of the virus into macrophages.

  9. mMGL1 preferentially binds Lewis X-conjugated soluble polyacrylamides

  10. Generation of mice deficient for macrophage galactose- and N-acetylgalactosamine-specific lectin: limited role in lymphoid and erythroid homeostasis and evidence for multiple lectins.

  11. sialoadhesin acts as an endogenous counter-receptor for MGL1

  12. The mMGL1 protein is induced in diverse populations of aaMF, including peritoneal macrophages elicited during infection with the protozoan Trypanosoma brucei brucei or the Helminth Taenia crassiceps and alveolar macrophages elicited.

  13. MGL1 expressed on a specific subpopulation of macrophages that secrete IL-1alpha was proposed to regulate specific cellular interactions crucial to granulation tissue formation

  14. MGL1/CD301a is involved in the clearance of apoptotic cells

  15. analysis of protein-protein interactions in the Mgl-1 oncoprotein

  16. MGL1 mutants of Ala89Arg and Ala89Arg/Pro115Arg showed beta-GalNAc bindings.

  17. Carbohydrate binding mechanism of the macrophage galactose-type C-type lectin 1 revealed by saturation transfer experiments.(

  18. MGL1/CD301a plays a protective role against colitis

  19. MGL1 as a novel regulator of inflammatory monocyte trafficking to adipose tissue in response to diet-induced obesity.

CLEC10A 抗原简介

Antigen Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with CLEC10A

  • C-type lectin domain family 10 member A (LOC607405) 抗体
  • C-type lectin domain containing 10A (CLEC10A) 抗体
  • C-type lectin domain family 10, member A (Clec10a) 抗体
  • C-type lectin domain containing 10A (Clec10a) 抗体
  • CD301 抗体
  • CD301a 抗体
  • CLEC10A 抗体
  • CLECSF13 抗体
  • CLECSF14 抗体
  • HML 抗体
  • HML2 抗体
  • M-ASGP-BP-1 抗体
  • Mgl 抗体
  • Mgl1 抗体
  • Mgll 抗体

Protein level used designations for CLEC10A

C-type lectin domain family 10, member A , C-type lectin, superfamily member 14 , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived) , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived) , C-type lectin domain family 10 member A , macrophage lectin 2 (calcium dependent) , macrophage asialoglycoprotein-binding protein 1 , macrophage galactose N-acetyl-galactosamine specific lectin 1 , Gal/GalNAc-specific lectin , M-ASGP-BP , M-ASGP-BP-1 , MMGL , macrophage galactose/N-acetylgalactosamine-specific lectin , monoglyceride lipase

GENE ID SPECIES
607405 Canis lupus familiaris
748824 Pan troglodytes
10462 Homo sapiens
17312 Mus musculus
64195 Rattus norvegicus
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