anti-BR serine/threonine Kinase 2 (BRSK2) 抗体

Serine/threonine-protein kinase that plays a key role in polarization of neurons. 再加上,我们可以发BR serine/threonine Kinase 2 蛋白 (8)BR serine/threonine Kinase 2 试剂盒 (6)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
BRSK2 9024 Q8IWQ3
BRSK2 75770 Q69Z98
BRSK2 293631  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • 在线下订单
  • orders@antibodies-online.cn

antibodies-online.cn销售最多的anti-BR serine/threonine Kinase 2 抗体

Showing 10 out of 75 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
山羊 非结合性 ELISA   100 μg Log in to see 6至7个工作日
$291.53
详细
非结合性 ELISA, WB Western blot analysis of BRSK2 (Phospho-Thr260) using EGF treated RAW264.7 whole cell lysates 100 μL Log in to see 11至12个工作日
$450.00
详细
非结合性 IHC (p), WB Western blot analysis of anti-STK29 Pab(ABIN391285) in HL60 cell line lysate (35 µg/lane). STK29(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10至11个工作日
$385.00
详细
非结合性 ELISA, WB Western blot analysis of BRSK2 using HuvEc whole cell lysates 100 μL Log in to see 11至12个工作日
$390.77
详细
小鼠 非结合性 WB Mouse Brsk2 Antibody (Center)  western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the Brsk2 antibody detected the Brsk2 protein (arrow). 400 μL Log in to see 10至11个工作日
$385.00
详细
非结合性 IHC, ELISA, WB   100 μg Log in to see 15至19个工作日
$527.03
详细
非结合性 ELISA, WB   100 μL Log in to see 11至13个工作日
$335.04
详细
小鼠 非结合性 WB Western blot analysis in mouse testis tissue lysates (35ug/lane). 400 μL Log in to see 2至3个工作日
$515.63
详细
小鸡 山羊 非结合性 ELISA   100 μg Log in to see 11至14个工作日
$507.83
详细
非结合性 EIA, IHC (p), WB   0.1 mg Log in to see 4至8个工作日
$522.50
详细

引用最多的anti-BR serine/threonine Kinase 2 抗体

  1. Human Polyclonal BRSK2 Primary Antibody for IHC (p), WB - ABIN541299 : Manning, Whyte, Martinez, Hunter, Sudarsanam: The protein kinase complement of the human genome. in Science (New York, N.Y.) 2002 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal BRSK2 Primary Antibody for IHC, ELISA - ABIN1001943 : Lizcano, Göransson, Toth, Deak, Morrice, Boudeau, Hawley, Udd, Mäkelä, Hardie, Alessi: LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. in The EMBO journal 2004 (PubMed)
    Show all 4 Pubmed References

  3. Dog (Canine) Polyclonal BRSK2 Primary Antibody for ELISA - ABIN547548 : Kishi, Pan, Crump, Sanes: Mammalian SAD kinases are required for neuronal polarization. in Science (New York, N.Y.) 2005 (PubMed)

更多抗BR serine/threonine Kinase 2的相互作用对抗体

Human BR serine/threonine Kinase 2 (BRSK2) interaction partners

  1. the intrinsic molecular merit that BRSK2 provides is a survival advantage to PDAC cells and strengthens the invasiveness of these neoplastic cells in energy-deprived environments.

  2. SAD-A and AMPK kinases are regulators of mTORC1 signaling in the pancreatic beta-cells.

  3. BRSK2 interacted with VCP/p97 via three of the four functional domains of VCP/p97. Immunofluorescence demonstrated that BRSK2 and VCP/p97 were co-localized and also that knockdown of endogenous BRSK2 induced increased levels of CD3delta.

  4. Anaphase-promoting complex/cyclosome-Cdh1, rather than Cdc20, promotes the degradation of BRSK2 in vivo.

  5. a novel function of BRSK2 in the regulation of GSIS in beta-cells via a PCTAIRE1-dependent mechanism and suggest that BRSK2 is an attractive target for developing novel diabetic drugs.

  6. these findings demonstrate ER stress may reduce BRSK2 protein and change BRSK2 subcellular localization, which in turn alleviate ER stress-induced apoptosis.

  7. these findings provide a novel regulatory mechanism of BRSK2 through direct interaction with Jab1.

  8. BRSK2 is up-regulated in pancreatic ductal adenocarcinoma.

  9. BRSK2 may be an autoantigen involved in the pathogenesis of small-cell lung cancer-associated limbic encephalitis.

  10. we identified cAMP-dependent protein kinase A (PKA) as another upstream kinase of BRSK2, which can phosphorylate BRSK2 at Thr260. Kinase activity of BRSK2 can be increased through phosphorylation by PKA.

  11. protein phosphatase 2C is a likely candidate for catalyzing the dephosphorylation and inactivation of BRSK1/2.

  12. level of SAD within neurons is modulated by TORC1

  13. STRADalpha.MO25alpha complexes containing LKB1 variants were equally effective at phosphorylating and activating AMPK, BRSK1, and BRSK2

Mouse (Murine) BR serine/threonine Kinase 2 (BRSK2) interaction partners

  1. Glucose and incretin stimulate insulin secretion through the phosphorylation of GDIalpha at Ser174 by SAD-A, which leads to the activation of Rho GTPases, culminating in insulin exocytosis.

  2. Taken together, these data suggest a model for synergistic autoinhibition and membrane activation of SAD kinases.

  3. SAD-A and AMPK kinases are regulators of mTORC1 signaling in the pancreatic beta-cells.

  4. SAD-A and SAD-B kinases have multiple, sequential roles in axonal differentiation

  5. SAD-A kinase controls islet beta-cell size and function as a mediator of mTORC1 signaling.

  6. SAD-A kinase is a pancreas-specific mediator of incretin response in islet beta cells.

  7. a novel function of BRSK2 in the regulation of GSIS in beta-cells via a PCTAIRE1-dependent mechanism and suggest that BRSK2 is an attractive target for developing novel diabetic drugs.

  8. a critical role of SAD-A in the activation of PAK1 during the onset of insulin exocytosis.

  9. The regulation of Wee1 by SadA and SadB kinases is essential for the differentiation of polarized neurons.

  10. results show that SAD-A and SAD-B, mammalian orthologs of a kinase needed for presynaptic differentiation in Caenorhabditis elegans, are required for neuronal polarization.

  11. Once activated, LKB1 phosphorylates and thereby activates SAD-A and SAD-B kinases, which are also required for neuronal polarization in the cerebral cortex.

BR serine/threonine Kinase 2 (BRSK2) 抗原简介

蛋白简介

Serine/threonine-protein kinase that plays a key role in polarization of neurons. Phosphorylates MAPT/TAU and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Ser-554'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity in polarized neurons.

Gene names and symbols associated with BRSK2

  • BR serine/threonine kinase 2 (BRSK2) 抗体
  • BR serine/threonine kinase 2 (Brsk2) 抗体
  • 4833424K13Rik 抗体
  • BRSK2 抗体
  • C11orf7 抗体
  • PEN11B 抗体
  • SAD-A 抗体
  • SAD1 抗体
  • SADA 抗体
  • STK29 抗体

Protein level used designations for BRSK2

BR serine/threonine-protein kinase 2 , brain-selective kinase 2 , brain-specific serine/threonine-protein kinase 2 , protein kinase SAD1B , serine/threonine-protein kinase 29 , serine/threonine-protein kinase BRSK2 , serine/threonine-protein kinase SAD-A , BR serine/threonine kinase 2 , BR serine/threonine-protein kinase 2-like , brain serine/threonine kinase 2

GENE ID SPECIES
9024 Homo sapiens
423098 Gallus gallus
535868 Bos taurus
746226 Pan troglodytes
100395256 Callithrix jacchus
100429659 Macaca mulatta
100443903 Pongo abelii
75770 Mus musculus
293631 Rattus norvegicus
483658 Canis lupus familiaris
anti-BR serine/threonine Kinase 2 (BRSK2) 抗体 精选生产商
您还需要查找其他产品吗?