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BAMBI encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. 再加上，我们可以发BAMBI 试剂盒 (14) 和 BAMBI 蛋白 (12)和数多这个蛋白质的别的产品。
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Human Monoclonal BAMBI Primary Antibody for ELISA, WB - ABIN565170
Tramullas, Lantero, Díaz, Morchón, Merino, Villar, Buscher, Merino, Hurlé, Izpisúa-Belmonte, Hurlé: BAMBI (bone morphogenetic protein and activin membrane-bound inhibitor) reveals the involvement of the transforming growth factor-beta family in pain modulation. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010
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Human Polyclonal BAMBI Primary Antibody for FACS, IF (p) - ABIN1714490
Bai, Chu, Mai, Zheng, Wang, Zhang, Yang: Identification and expression analyses of BAMBI mediated by FSH in swine luteinizing granulosa cells. in Theriogenology 2014
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BAMBI promotes macrophage proliferation and differentiation in gliomas.
These results showed that BMP2 (显示 BMP2 抗体) activated SMAD1 (显示 GARS 抗体)/5/8 phosphorylation and up-regulated BAMBI mRNA in human granulosa-lutein cells.
Data show that BAMBI is expressed in both circulating CD4 (显示 CD4 抗体)+ T cells and plasma and may be characterized as a novel immune regulator for COPD (显示 ARCN1 抗体). Strikingly, BAMBI expression was significantly stronger in COPD (显示 ARCN1 抗体) patients and displayed strong correlations with enhanced plasma TGF-beta 1 (显示 TGFB1 抗体) levels and the Th17/Treg ratio.
Lipopolysaccharides-mediated TLR4 (显示 TLR4 抗体) signaling enhances TGF-beta (显示 TGFB1 抗体) response through downregulating BAMBI during prostatic hyperplasia.
TGFbeta (显示 TGFB1 抗体) target genes including TGFBI (显示 TGFBI 抗体), BAMBI, COL3A1 (显示 COL3A1 抗体) and SERPINE1 (显示 SERPINE1 抗体) are significantly increased in Diamond Blackfan Anemia induced pluripotent stem cells
The observations illuminated that BAMBI inhibits adipogenesis by a feedback loop (BAMBI-->beta-catenin (显示 CTNNB1 抗体) nuclear translocation-->BAMBI), which forms with Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling.
betacatenin expression was downregulated as a result of knocking down of BAMBI, and TGF-beta (显示 TGFB1 抗体) was downregulated in a similar manner.
BAMBI alone or in combination with Smad7 (显示 SMAD7 抗体) was significantly associated with the OS and DFS (显示 FST 抗体). These findings suggest that BAMBI and Smad7 (显示 SMAD7 抗体) may cooperatively inhibit the TGF-beta (显示 TGFB1 抗体) signaling, and thus promote the progression of gastric cancer.
study demonstrates that LPS (显示 IRF6 抗体)- and TNF-alpha (显示 TNF 抗体)-induced NF-kappaBp50-HDAC1 (显示 HDAC1 抗体) interaction represses BAMBI transcriptional activity, which contributes to TLR4 (显示 TLR4 抗体)-mediated enhancement of TGF-beta (显示 TGFB1 抗体) signaling in hepatic stellate cells during liver fibrosis.
Overexpression of BAMBI is associated with the growth and invasion of human osteosarcoma.
results indicated that BMP and activin membrane-bound inhibitor homolog(BAMBI) is an FSH (显示 BRD2 抗体)-repressed gene in porcine luteinizing granulosa cells and it may be involved in the regulation of ovarian follicle development and oocyte maturation
This study shows that upregulation of bigh3 and bambia mRNA correlated with the process of fin regeneration and regulation of TGF-b signaling, suggesting a new role for these proteins.
BAMBI is required for normal C2C12 differentiation, and that its role in myogenesis is mediated by the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) pathway.
BAMBI modulates the effects of diabetes on glomerular permselectivity in association with altered ERK1/2 and Smad1 (显示 SMAD1 抗体)/5 signaling.
these results provide strong evidence for an important role of endothelium rather than platelet BAMBI as a positive regulator of both thrombus formation and stability.
we provide in vitro and in vivo evidence that BAMBI contributes to endothelial and vascular homeostasis
suggest that BAMBI is involved in negative feedback loops that restrain the TGF-beta (显示 TGFB1 抗体) remodeling signals to protect the pressure-overloaded myocardium from uncontrolled extracellular matrix deposition in humans and mice
BAMBI protein is expressed in endothelial cells and is regulated by autophagy and lysosomal degradation.
Transcript levels of TGF-betas and their intracellular effectors correlated directly with genes encoding opioid peptides, whereas BAMBI correlated inversely.
Overexpression of Nma/BAMBI in mouse odontoblast-like cell line MD10-A2 down-regulated expression of DSPP (显示 DSPP 抗体) by 66% and up-regulated expression of DMP1 (显示 DMP1 抗体) four-fold.
and has implications in tumor progression. Genomic organization of the mouse Nma/BAMBI gene and confirmed the chromosomal mapping to human chromosome 10 and mouse chromosome 2.
This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis.
BMP and activin membrane-bound inhibitor homolog
, non-metastatic gene A protein
, putative transmembrane protein NMA
, BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
, BMP and activin membrane-bound inhibitor, homolog
, kinase-deficient TGFbeta superfamily receptor subunit
, BAMBI protein (TGF-beta signalling)
, BMP and activin membrane-bound inhibitor L homeolog