anti-BMP Binding Endothelial Regulator (BMPER) 抗体

BMPER encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. 再加上,我们可以发BMPER 试剂盒 (19)BMPER 蛋白 (6)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
BMPER 168667 Q8N8U9
BMPER 73230 Q8CJ69
BMPER 300455  
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Showing 10 out of 35 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB 100 μL Log in to see 2至3个工作日
$289.00
详细
Bat 非结合性 IHC, IHC (p), WB Human Liver (formalin-fixed, paraffin-embedded) stained with BMPER antibody ABIN462252 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Lung, Respiratory Epithelium (formalin-fixed, paraffin-embedded) stained with BMPER antibody ABIN462252 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7至9个工作日
$727.83
详细
非结合性 ICC, IHC, WB Figure. Western Blot; Sample: Recombinant BMPER Human. Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Log in to see 13至16个工作日
$350.00
详细
小鼠 非结合性 ICC, IHC, WB Western Blot; Sample: Mouse Liver lysate; Primary Ab: 1µg/ml Rabbit Anti-Mouse BMPER Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) Figure. Western Blot; Sample: Recombinant BMPER, Human. 100 μg Log in to see 13至16个工作日
$360.00
详细
非结合性 ELISA, WB 50 μg Log in to see 2至3个工作日
$446.88
详细
非结合性 WB BMPER antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. Magnification is at 400X BMPER antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2至3个工作日
$510.36
详细
大鼠 非结合性 ELISA, WB   100 μg Log in to see 11至14个工作日
$925.83
详细
非结合性 ELISA, WB   200 μL Log in to see 11至16个工作日
$594.00
详细
PE ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
详细
FITC ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
详细

通过反应活性、应用领域、克隆类型和共轭标记 BMPER 抗体

特性 应用范围 宿主 克隆类型 标记
Human , ,
, ,
,
, , , , ,
Mouse (Murine)


Rat (Rattus)


更多抗BMPER的相互作用对抗体

Fruit Fly (Drosophila melanogaster) BMP Binding Endothelial Regulator (BMPER) interaction partners

  1. The bone morphogenetic protein- binding protein Cv-2 negatively regulates bone morphogenetic protein signaling.

  2. Cv-2 is a short-range, concentration-dependent, biphasic modulator of BMP signaling.

Zebrafish BMP Binding Endothelial Regulator (BMPER) interaction partners

  1. The NMR structure of the Danio rerio CV2 VWC1 (显示 VWCE 抗体) domain in its unbound state shows the key features for high affinity binding to BMP-2 (显示 BMP4 抗体) are a pre-oriented peptide loop.

  2. Crossveinless 2 functions in a positive-feedback loop to locally enhance BMP activity and is required for neural crest fate determination.

  3. LRP1 (显示 LRP1 抗体) acts as an endocytic receptor for Bmper and a coreceptor of Bmp4 (显示 BMP4 抗体) to mediate the endocytosis of the Bmper/Bmp4 (显示 BMP4 抗体) signaling complex.

  4. Binding of CV2 to Chordin (显示 CHRD 抗体) promotes BMP-2 (显示 BMP4 抗体) signaling.

  5. Cvl2 was identified as an essential pro-bone morphogenetic protein factor during zebrafish embryogenesis.

  6. Bmper is a conserved regulator of hematopoietic and vascular development in zebrafish.

  7. Initial crystallographic analysis suggests that a complete binary complex consisting of one BMP2 (显示 BMP4 抗体) dimer bound to two crossveinless 2 (CV2) von Willebrand type C (VWC1 (显示 VWCE 抗体)) domains is present in the asymmetric unit.

  8. The structure of the complex between CV-2 Von Willebrand factor (显示 VWF 抗体) type C (VWC) domain 1 and BMP-2 (显示 BMP4 抗体), is reported.

Xenopus laevis BMP Binding Endothelial Regulator (BMPER) interaction partners

  1. CV2/Chordin interaction may help coordinate bone morphogenetic protein (BMP) diffusion to the ventral side of the embryo, ensuring that BMPs liberated from Chordin inhibition by tolloid proteolysis cause peak signaling levels.

Human BMP Binding Endothelial Regulator (BMPER) interaction partners

  1. Overexpression of BMPER remarkably enhanced BMP-2 (显示 BMP2 抗体)-induced osteogenic differentiation, while suppression of BMPER effectively inhibited this process both in vitro and in vivo.

  2. that BMPER-modulated BMP pathway activity regulates VE-cadherin (显示 CDH5 抗体) expression and vascular barrier function

  3. BMPER variants associated with a novel, attenuated subtype of diaphanospondylodysostosis.

  4. BMPER-dependent pathway involved in high glucose induced alkaline phosphatase expression in vascular smooth muscle cells.

  5. The proangiogenic BMPER effect in endothelial cells is mediated by inhibition of antiangiogenic thrombospondin-1 (显示 THBS1 抗体) and enhanced expression and activation of the FGF signaling pathway that is crucial in the promotion of angiogenesis.

  6. these results suggest that BMPER and Tsg maintain a fine-tuned equilibrium that controls BMP pathway activity and is necessary for vascular cell homeostasis.

  7. BMPER is a novel regulator of the osteoblast-like differentiation of HCASMCs.

  8. Bmper is a critical regulator of Bmp-mediated vascular inflammation and that the fine-tuning of Bmp and Bmper levels is essential in the maintenance of normal vascular homeostasis.

  9. The data unequivocally demonstrated that BMPER is highly expressed in malignant tumors and that the growth of lung, colon, and uterine carcinomas is dependent on the presence of BMPER.

  10. Mutual regulation by BMP-9 (显示 GDF2 抗体) and CV2 is essential in regulating the development of the vascular endothelium.

Cow (Bovine) BMP Binding Endothelial Regulator (BMPER) interaction partners

  1. Results identified variant SNPs in BMPER gene associated with phenotypic variation in cattle that can be used as genetic markers for breeding.

Pig (Porcine) BMP Binding Endothelial Regulator (BMPER) interaction partners

  1. BMPER promoter polymorphisms have an effect on the intramuscular fat deposition in longissimus dorsi muscle content.

Mouse (Murine) BMP Binding Endothelial Regulator (BMPER) interaction partners

  1. BMPER contributes to the precise control of BMP activity within the aorta-gonad-mesonephros region, enabling the maturation of hematopoietic stem cells within a BMP-negative environment.

  2. CV2 binds directly to BMP10 (显示 BMP10 抗体), as determined by co-immunoprecipitation, and inhibits BMP10 (显示 BMP10 抗体) from initiating SMAD (显示 SMAD1 抗体) signaling, as determined by luciferase reporter gene assays. BMP10 (显示 BMP10 抗体) and CV2 have important roles in coordinating cardiomyogenesis in progenitor cells.

  3. BMPER/low-density lipoprotein receptor-related protein 1 (显示 LRP1 抗体) axis plays a pivotal role in pulmonary inflammatory response.

  4. The proangiogenic BMPER effect in endothelial cells is mediated by inhibition of antiangiogenic thrombospondin-1 (显示 THBS1 抗体) and enhanced expression and activation of the FGF signaling pathway that is crucial in the promotion of angiogenesis.

  5. BMPER-induced BMP signaling promotes coronary artery remodeling.

  6. BMPER appears to play a role in regulating both vessel density and cardiac development

  7. BMPER expression is decreased following lung injury, which in turn impairs epithelial integrity, characterized by reduction of E-cadherin (显示 CDH1 抗体) and epithelial leakage in vitro and in vivo.

  8. Bmper is a critical regulator of Bmp-mediated vascular inflammation and that the fine-tuning of Bmp and Bmper levels is essential in the maintenance of normal vascular homeostasis.

  9. The data unequivocally demonstrated that BMPER is highly expressed in malignant tumors and that the growth of lung, colon, and uterine carcinomas is dependent on the presence of BMPER.

  10. Bmper may play an important role in suppressing hepcidin (显示 HAMP 抗体) production in hypotransferrinemic mice.

BMPER 抗原简介

蛋白简介

This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis.

Gene names and symbols associated with BMPER

  • BMP binding endothelial regulator (BMPER) 抗体
  • crossveinless 2 (cv-2) 抗体
  • BMP binding endothelial regulator (bmper) 抗体
  • BMP-binding endothelial regulator protein (LOC100070275) 抗体
  • crossveinless 2 (cv2) 抗体
  • BMP binding endothelial regulator L homeolog (bmper.L) 抗体
  • BMP-binding endothelial regulator (Bmper) 抗体
  • 3110056H04Rik 抗体
  • BMPER 抗体
  • CG15671 抗体
  • Crim3 抗体
  • CT35855 抗体
  • CV-2 抗体
  • cv2 抗体
  • cv 2 抗体
  • cvl2 抗体
  • Dmel\\CG15671 抗体
  • id:ibd5071 抗体
  • RGD1563373 抗体

Protein level used designations for BMPER

BMP-binding endothelial regulator precursor protein , CG15671-PA , crossveinless-2 , cv-2-PA , BMP binding endothelial regulator , crossveinless 2 , BMP-binding endothelial regulator protein-like , BMP-binding endothelial regulator protein , cv2 , bone morphogenetic protein-binding endothelial cell precursor-derived regulator , hCV2

GENE ID SPECIES
100225434 Taeniopygia guttata
100349327 Oryctolagus cuniculus
45280 Drosophila melanogaster
463344 Pan troglodytes
733449 Xenopus (Silurana) tropicalis
100070275 Equus caballus
100303516 Saccoglossus kowalevskii
100415378 Callithrix jacchus
100472873 Ailuropoda melanoleuca
100605182 Nomascus leucogenys
338246 Danio rerio
734166 Xenopus laevis
420744 Gallus gallus
168667 Homo sapiens
534101 Bos taurus
475280 Canis lupus familiaris
100525197 Sus scrofa
73230 Mus musculus
300455 Rattus norvegicus
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