(B-Cell Scaffold Protein with Ankyrin Repeats 1 (BANK1))
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
Bernal-Quirós, Wu, Alarcón-Riquelme, Castillejo-López: "BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling." in: PLoS ONE, Vol. 8, Issue 3, pp. e59842, (2013) (PubMed).
Aliases for BANK1 抗体
B-cell scaffold protein with ankyrin repeats 1 (Bank1) 抗体 B-cell scaffold protein with ankyrin repeats 1 (BANK1) 抗体 B cell scaffold protein with ankyrin repeats 1 (Bank1) 抗体 A530094C12Rik 抗体 AI451642 抗体 AVIEF 抗体 BANK 抗体 LRRGT00104 抗体