anti-Atonal Homolog 7 (Drosophila) (ATOH7) 抗体

This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. 再加上,我们可以发ATOH7 蛋白 (6)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ATOH7 365564  
ATOH7 53404 Q9Z2E5
ATOH7 220202 Q8N100
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Showing 10 out of 73 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-ATOH7 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  THP-1 cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
小鼠 非结合性 WB WB Suggested Anti-Atoh7 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Mouse Heart 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: ATOH7 Antibody [NBP1-88639] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli. Immunohistochemistry-Paraffin: ATOH7 Antibody [NBP1-88639] - Staining of human colon shows strong membranous positivity in glandular cells. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
Cow 非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 ELISA, IHC, IHC (fro), WB Immunofluorescent staining of differentiated neural stem cells (Mouse) showing localization of ATH5.  1. Dissect tissues and freeze on dry ice 2. Cut on a cryostat - 10um slices 3. Dry slides at RT for 30-90 min 4. Fix with cold Acetone/Methanol (50/50) 2 min - then either process further or store at -20°C . Alternative is fixation with 4% PFA and treatment with a trypsin solution. (0.05% trypsin, incubation 10 minutes at 37°C, followed by 3 washes with PBS) 5. Let air dry 6. PBS 5min 7. Incubate in 50mM ammonium chloride 30 min 8. PBS 5min 9. Blocking serum 30-45min 10. Primary antibody 90min - dilution 1:100 - 1:600 11. Wash 3 times for 5 min 12. Secondary fluorescent conjug. antibody 30min 13. Wash 3 times for 5 min and mount 100 μg Log in to see 7至9个工作日
$925.83
详细
非结合性 WB Western blot analysis in A2058 cell line lysates (35ug/lane). 400 μL Log in to see 2至3个工作日
$515.63
详细
小鼠 非结合性 WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (31.06 KDa) . Dilution: 1:500~1000 Western Blot analysis of ATOH7 expression in transfected 293T cell line by ATOH7 monoclonal antibody (M02), clone 1E5.Lane 1: ATOH7 transfected lysate(16.9 KDa).Lane 2: Non-transfected lysate. Dilution: 1:500~1000 100 μg Log in to see 8至11个工作日
$461.00
详细
小鼠 非结合性 WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (31.06 KDa) . Dilution: 1:500~1000 Western Blot analysis of ATOH7 expression in transfected 293T cell line by ATOH7 monoclonal antibody (M01), clone 1A5.Lane 1: ATOH7 transfected lysate(16.9 KDa).Lane 2: Non-transfected lysate. Dilution: 1:500~1000 100 μg Log in to see 8至11个工作日
$461.00
详细
斑马鱼 山羊 非结合性 ELISA   100 μg Log in to see 7至9个工作日
$507.83
详细
Hamster 山羊 非结合性 ELISA   100 μg Log in to see 7至9个工作日
$507.83
详细

引用最多的anti-ATOH7 抗体

  1. Human Polyclonal ATOH7 Primary Antibody for WB - ABIN531345 : Prasov, Brown, Glaser: A critical analysis of Atoh7 (Math5) mRNA splicing in the developing mouse retina. in PLoS ONE 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal ATOH7 Primary Antibody for ELISA, WB - ABIN531346 : Prasov, Masud, Khaliq, Mehdi, Abid, Oliver, Silva, Lewanda, Brodsky, Borchert, Kelberman, Sowden, Dattani, Glaser: ATOH7 mutations cause autosomal recessive persistent hyperplasia of the primary vitreous. in Human molecular genetics 2012 (PubMed)

  3. Cow (Bovine) Polyclonal ATOH7 Primary Antibody for WB - ABIN2775072 : McLellan, Langlands, Kealey: Exhaustive identification of human class II basic helix-loop-helix proteins by virtual library screening. in Mechanisms of development 2003 (PubMed)

  4. Human Polyclonal ATOH7 Primary Antibody for ELISA - ABIN451594 : Brown, Dagenais, Chen, Glaser: Molecular characterization and mapping of ATOH7, a human atonal homolog with a predicted role in retinal ganglion cell development. in Mammalian genome : official journal of the International Mammalian Genome Society 2002 (PubMed)

  5. Zebrafish (Danio rerio) Polyclonal ATOH7 Primary Antibody for ELISA - ABIN451523 : Kay, Link, Baier: Staggered cell-intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina. in Development (Cambridge, England) 2005 (PubMed)

  6. Human Polyclonal ATOH7 Primary Antibody for ICC, IF - ABIN4282208 : Miesfeld, Glaser, Brown: The dynamics of native Atoh7 protein expression during mouse retinal histogenesis, revealed with a new antibody. in Gene expression patterns : GEP 1970 (PubMed)

更多抗ATOH7的相互作用对抗体

Zebrafish Atonal Homolog 7 (Drosophila) (ATOH7) interaction partners

  1. Atoh7 indirectly impacts amacrine-cell division modes to regulate the right number of Barhl2 (显示 BARHL2 抗体)-expressing cells. Atoh7 itself influences the subtypes of Barhl2 (显示 BARHL2 抗体)-dependent amacrine cells.

  2. Observations suggest that Irx2 (显示 IRX2 抗体) functions downstream of irx1a (显示 IRX1 抗体) to control shh (显示 SHH 抗体) expression in the retina. Study proposed a novel transcriptional cascade of ath5-irx1a (显示 IRX1 抗体)-irx2a in the regulation of hedgehog (显示 SHH 抗体) waves during vertebrate retinal development.

  3. Staggered cell-intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina.

Mouse (Murine) Atonal Homolog 7 (Drosophila) (ATOH7) interaction partners

  1. The transient features of Atoh7 protein expression during retinal neurogenesis match the expected pattern at the tissue and cellular level.

  2. Pou4f2 (显示 POU4F2 抗体) and Isl1 (显示 ISL1 抗体), are sufficient to specify the retinal ganglion cell fate in ATOH7 deficient mice

  3. This study present evidence for a Pax6 (显示 PAX6 抗体)-Atoh7-Eya2 (显示 EYA2 抗体) pathway that acts downstream of Atoh7 but upstream of differentiation factor Pou4f2 (显示 POU4F2 抗体).

  4. Notch (显示 NOTCH1 抗体) signaling controls the overall tempo of retinogenesis through Atoh7 and Neurog2 (显示 NEUROG2 抗体), by integrating cell fate specification, the wave of neurogenesis and the developmental status of cells ahead of this wave

  5. The level of basic helix-loop-helix factor Math5 expression may determine the ultimate number of retinal ganglion cells.

  6. Atoh7 acts dominantly in Neurod1-expressing retina progenitor cells to activate the retinal ganglion cell genetic program.

  7. Results suggest that Math5 is not sufficient to stimulate retinal ganglion cell (RGC)fate.

  8. new insights into Math5 function, ganglion cell development, and the mechanism of retinal fate determination were provided.

  9. The present data demonstrates that the loss of ganglion cells in the Math5(-/-) mice is associated with a lack of retinal vascular development.

  10. Report Math5 expression/function in retinal ganglion cells.

Human Atonal Homolog 7 (Drosophila) (ATOH7) interaction partners

  1. In conclusion, we have identified a homozygous mutation in the ATOH7 gene in a patient with nonsyndromic congenital retinal nonattachment.

  2. We evaluated 21 consanguineous NCRNA pedigrees and identified the causal mutations in known retinal genes in 13 out of our 21 families. We found mutations in ATOH7 in three families.

  3. We discovered a novel SNP, rs56238729 (P = 1.22 x 10-13), in the ATOH7-PBLD (显示 PBLD 抗体) region that is significantly associated with VCDR in Latino individuals.

  4. The genotype and allele frequencies of the polymorphism in ATOH7 did not show any statistically significant association with primary open angle glaucomacompared to controls.

  5. Familial linkage studies for primary angle-closure glaucoma have been performed and identified ATOH7 causative primary angle-closure glaucoma disease

  6. Single nucleotide polymorphism in ATOH7 gene is associated with primary open angle glaucoma.

  7. The significant association of three common variants in TMCO1 (显示 TMCO1 抗体), ATOH7, and CAV1 (显示 CAV1 抗体) with primary open angle, primary angle closure, and pseudoexfoliation glaucoma was found in Pakistani cohorts.

  8. Mutations within the ATOH7 gene are not implicated in the pathogenesis of optic nerve hypoplasia in our patient cohort.

  9. This study finds that ATOH7 is associated with optic disc size but not independently with cup/disk ratio.

  10. a bHLH mutation in ATOH7 causes recessive persistent hyperplasia of the primary vitreous

ATOH7 抗原简介

蛋白简介

This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment.

Gene names and symbols associated with ATOH7

  • atonal bHLH transcription factor 7 (Atoh7) 抗体
  • atonal bHLH transcription factor 7 (ATOH7) 抗体
  • atonal bHLH transcription factor 7 (atoh7) 抗体
  • ATH5 抗体
  • ATOH7 抗体
  • bHLHa13 抗体
  • Math5 抗体
  • zath5 抗体

Protein level used designations for ATOH7

atonal homolog 7 , atonal homolog 7 (Drosophila) , atonal homolog 5 , helix-loop-helix protein zATH-5 , lak , lakritz , protein atonal homolog 5 , protein atonal homolog 7 , protein lakritz , helix-loop-helix protein mATH-5 , class A basic helix-loop-helix protein 13 , helix-loop-helix protein hATH-5 , Atonal Homolog 5 , atonal transcription factor homologue , cATH5 , helix-loop-helix protein cATH-5

GENE ID SPECIES
365564 Rattus norvegicus
466090 Pan troglodytes
489014 Canis lupus familiaris
539903 Bos taurus
100230256 Taeniopygia guttata
100342736 Oryctolagus cuniculus
58216 Danio rerio
53404 Mus musculus
220202 Homo sapiens
395388 Gallus gallus
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