Actin, gamma 2, Smooth Muscle, Enteric (ACTG2) ELISA试剂盒

Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. 再加上,我们可以发ACTG2 抗体 (54)ACTG2 蛋白 (9)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
ACTG2 72 P63267
ACTG2 11468 P63268
ACTG2 25365 P63269
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7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Log in to see 15至18个工作日
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适于 ACTG2 相互作用对的更多 ELISA 试剂盒

Human Actin, gamma 2, Smooth Muscle, Enteric (ACTG2) interaction partners

  1. Whole exome and Sanger sequencing revealed a pathogenic variant in the ACTG2 gene in 4 out of 28 probands with chronic intestinal pseudo-obstruction and megacystis. Moreover, a mutational hotspot in the ACTG2 gene was recognized. Genetic heterogeneity is evident.

  2. R257 variant in the ACTG2 appear to be more frequent in populations of Asian ancestry; mutation of this locus could cause alterations of the intestinal and bladder smooth muscle filaments.

  3. ACTG2 boosts the metastatic potential of hepatocellular carcinoma in a Notch1 (显示 NOTCH1 ELISA试剂盒)-dependent manner.

  4. Missense variants in ACTG2 were identified in the patients with either megacystis-microcolon-intestinal hypoperistalsis syndrome or intestinal pseudo-obstruction.

  5. A heterozygous missense variant in ACTG2 was identified that impaired actin polymerization in sporadic Megacystis microcolon intestinal hypoperistalsis syndrome.

  6. ACTG2 is expressed in a fraction of small intestinal neuroendocrine tumors, can inhibit cell growth in vitro, and is positively regulated by miR (显示 MLXIP ELISA试剂盒)-145.

  7. Mutations within ACTG2 are associated with fetal megacystis in microcolon intestinal hypoperistalsis syndrome.

  8. Phenotypic spectrum of ACTG2 missense variants involved severe pathology in multiple smooth muscle-dependent organs including the biliary tract and the uterus in the family with visceral myopathy.

  9. gammaSMA expression in hepatocellular carcinoma is strongly correlated with the EMT process, HCC aggressiveness and the identification of cancer stem cells

  10. ACTG2 encodes g2 enteric actin and is the first gene to be clearly associated with Megacystis-microcolon-intestinal hypoperistalsis syndrome, suggesting an important role for contractile proteins in enteric smooth muscle disease.

Mouse (Murine) Actin, gamma 2, Smooth Muscle, Enteric (ACTG2) interaction partners

  1. ACTG2 boosts the metastatic potential of hepatocellular carcinoma in a Notch1 (显示 NOTCH1 ELISA试剂盒)-dependent manner.

  2. MYOCD (显示 MYOCD ELISA试剂盒) can discriminate among several juxtaposed CArG elements, presumably through its novel partnership with NKX3.1 (显示 NKX3-1 ELISA试剂盒), to optimally transactivate the human ACTG2 promoter

ACTG2 抗原简介

Antigen Summary

Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2\; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.

Gene names and symbols associated with ACTG2

  • actin, gamma 2, smooth muscle, enteric (ACTG2) 抗体
  • actin, gamma 2, smooth muscle, enteric (Actg2) 抗体
  • ACT 抗体
  • Act-4 抗体
  • Act4 抗体
  • ACTA3 抗体
  • ACTE 抗体
  • ACTG2 抗体
  • ACTGE 抗体
  • ACTL3 抗体
  • ACTSG 抗体
  • GAMMA-ACTIN 抗体
  • SMGA 抗体

Protein level used designations for ACTG2

actin, gamma 2, smooth muscle, enteric , actin, gamma-enteric smooth muscle , alpha-actin-3 , gamma-2-actin , smooth muscle gamma-actin , actin-like protein , alpha-actin 3 , smooth muscle gamma actin , actin, gamma-enteric smooth muscle-like , actin, gamma 2 propeptide-like , alpha-smooth muscle actin , gamma-enteric smooth muscle actin

GENE ID SPECIES
739500 Pan troglodytes
475792 Canis lupus familiaris
100057561 Equus caballus
707447 Macaca mulatta
396084 Gallus gallus
281595 Bos taurus
72 Homo sapiens
11468 Mus musculus
100404219 Callithrix jacchus
100350318 Oryctolagus cuniculus
25365 Rattus norvegicus
100581173 Nomascus leucogenys
100716255 Cavia porcellus
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