(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 (ABCC6))
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008].
Scheffer, Hu, Pijnenborg, Wijnholds, Bergen, Scheper: "MRP6 (ABCC6) detection in normal human tissues and tumors." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 82, Issue 4, pp. 515-8, (2002) (PubMed).
Bergen, Plomp, Schuurman, Terry, Breuning, Dauwerse, Swart, Kool, van Soest, Baas, ten Brink, de Jong: "Mutations in ABCC6 cause pseudoxanthoma elasticum." in: Nature genetics, Vol. 25, Issue 2, pp. 228-31, (2000) (PubMed).
Pinckard, Sheehan, Arthur, Schreiber: "Constitutive shedding of both p55 and p75 murine TNF receptors in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 8, pp. 3869-73, (1997) (PubMed).
Aliases for ABCC6 抗体
ATP binding cassette subfamily C member 6 (ABCC6) 抗体 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (Abcc6) 抗体 ATP binding cassette subfamily C member 6 (Abcc6) 抗体 ABC34 抗体 Abcc1b 抗体 ARA 抗体 DCC 抗体 dyscalc 抗体 Dyscalc1 抗体 EST349056 抗体 GACI2 抗体 MLP1 抗体 MOAT-E 抗体 MOATE 抗体 MRP6 抗体 Mrp6 抗体 PXE 抗体 PXE1 抗体 URG7 抗体