ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) ELISA试剂盒

The protein encoded by ABCA7 is a member of the superfamily of ATP-binding cassette (ABC) transporters.

list all ELISA KIts 基因 基因ID UniProt
小鼠 ABCA7 ABCA7 27403 Q91V24
 ABCA7 ABCA7 10347 Q8IZY2
大鼠 ABCA7 ABCA7 299609 Q7TNJ2
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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
0.045 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 2至3个工作日
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小鼠 0.156-10 ng/mL   96 Tests Log in to see 2至3个工作日
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大鼠 < 0.071 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11至18个工作日
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适于 ABCA7 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) interaction partners

  1. ABCA7 does not play a significant role in the regulation of cell proliferation or neurogenesis in the adult mouse.

  2. This study demonstrated that novel mechanism underlying how dysfunctions of ABCA7 contribute to the risk for alzheimer disease.

  3. ABCA7 has a role in Alzheimer amyloid processing

  4. Theresults of this study suggested that ABCA7 plays a role in the regulation of Abeta (显示 APP ELISA试剂盒) homeostasis in the brain and that this may be related to altered phagocyte function.

  5. ABCA7 may play a role in T cell proliferation and erythropoeisis in spleen

  6. concluded that statins enhance macrophage phagocytosis through the SREBP-ABCA7 pathway.

  7. Data suggest that extracellular helical apolipoproteins augment ABCA7-associated phagocytosis by stabilizing ABCA7, and show direct enhancement of the host defense system by HDL (显示 HSD11B1 ELISA试剂盒) components.

  8. ABCA7 has the ability to bind apolipoproteins and promote efflux of cellular phospholipids without cholesterol, and has a possible role of ABCA7 in cellular phospholipid metabolism in peripheral tissues

  9. genetic knockdown of ABCA7 in mouse peritoneal macrophages did not affect phospholipid or cholesterol efflux to apoA-I (显示 APOA1 ELISA试剂盒)

  10. ABCA7 plays a novel role in lipid and fat metabolism

Human ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7) interaction partners

  1. Study investigated the association between ABCA7 rs3764650 SNP and blood lipid levels in Southern Chinese Han sporadic Alzheimer's disease population, and found GG genotype was a risk factor of sporadic Alzheimer's disease as well as lipid homeostasis.

  2. The primary findings of this report are that abnormal ABCA7 exon 41 splicing is found in the brain of an individual carrying the minor C allele of rs200538373 and that rs200538373 is a functional SNP

  3. rs3764650 ABCA7 is not associated with late-onset Alzheimer's disease.

  4. Study uses targeted sequencing of ABCA7 to identify splicing, stop-gain and intronic risk variants for Alzheimer disease. Study shows that multiple variants in ABCA7 contribute to late-onset Alzheimer's disease risk.

  5. ABCA7 PTC (显示 F9 ELISA试剂盒) mutations play a substantial role in early-onset Alzheimer disease, warranting genetic screening of ABCA7 in genetically unexplained patients.

  6. This study demonstrated that Genetic Variations in ABCA7 Can Increase Secreted Levels of Amyloid-beta40 and Amyloid-beta42 Peptides and ABCA7 Transcription in Cell Culture Models.

  7. The major difference in the pattern of lipid peaks between ABCA7 and ABCA1 (显示 ABCA1 ELISA试剂盒) was the high lysoPC/PC ratio of ABCA7.

  8. Results confirm that ABCA7 loss of function variants are enriched in patients with Alzheimer disease and extend this finding to predicted damaging missense variants

  9. A detailed clinicopathologic description of patients carrying an ABCA7 loss of function mutation: a classical Alzheimer disease phenotype, though with a striking wide onset age range, suggesting the influence of unknown modifying factors

  10. Results suggested that ABCA7 genotypes contribute to the AD risk through involvement in amyloid-beta deposition on in vivo imaging, but not in tau pathology, brain atrophy, or decreased glucose metabolism

ABCA7 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known\; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system.

Gene names and symbols associated with ABCA7

  • ATP-binding cassette, sub-family A (ABC1), member 7 (Abca7) 抗体
  • ATP binding cassette subfamily A member 7 (ABCA7) 抗体
  • ATP binding cassette subfamily A member 7 (Abca7) 抗体
  • ATP-binding cassette sub-family A member 7 (LOC100088822) 抗体
  • Abc51 抗体
  • ABCA-SSN 抗体
  • ABCA7 抗体
  • ABCX 抗体

Protein level used designations for ABCA7

ATP-binding cassette sub-family A member 7 , autoantigen SS-N , macrophage ABC transporter , ATP-binding cassette, sub-family A (ABC1), member 7 , ATP-binding cassette, sub-family A, member 7

GENE ID SPECIES
27403 Mus musculus
10347 Homo sapiens
299609 Rattus norvegicus
511762 Bos taurus
455538 Pan troglodytes
485090 Canis lupus familiaris
704976 Macaca mulatta
100088822 Ornithorhynchus anatinus
100623892 Sus scrofa
100726877 Cavia porcellus
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