AKT Interacting Protein (AKTIP) ELISA试剂盒

The mouse homolog of AKTIP produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. 再加上,我们可以发AKTIP 抗体 (77)AKTIP 蛋白 (12)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
AKTIP 64400 Q9H8T0
AKTIP 291906 Q5FVH4
AKTIP 14339 Q64362
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Human AKT Interacting Protein (AKTIP) interaction partners

  1. Results show that AKTIP co-purifies with A- and B-type lamins and partially co-localizes with lamins in interphase nuclei. In addition, AKTIP depletion lowers lamin A expression and induces senescence hallmarks including telomere homeostasis in human primary fibroblasts.

  2. results suggest that AKT1, FTO, and AKTIP polymorphisms were not associated with obesity/overweight in Brazilians children.

  3. FTS is involved in EGFR-mediated repair of DNA damage induced by cisplatin in ME180 cells

  4. AKTIP interacts with telomeric DNA and is required for telomere maintenance.

  5. High fused toes homolog expression is associated with radioresistance in cervical cancer.

  6. FTS silencing reduced EMT and cell migration by EGF treatment. These results demonstrate a novel function for FTS in EGF-mediated EMT process.

  7. *AKTIP single nucleotide polymorphisms are not associated with late-onset depression patients compared to healthy elderly controls.

  8. Targeted inhibition of FTS led to the shutdown of key elemental characteristics of cervical cancer and could lead to an effective therapeutic strategy.

  9. These data unraveled the involvement of new oncoprotein FTS in cervical cancer which plays a central role in carcinogenesis.

  10. Demographic and clinical characteristics and AKT1 single markers and haplotypes, but not AKTIP polymorphisms or interactions between AKT1 and AKTIP, are associated with increased risk for suicidal behavior in bipolar patients.

  11. Ft1 protein interacts directly with PKB, enhancing the phosphorylation of both of its regulatory sites by promoting its interaction with the upstream kinase PDK1

  12. These data suggest that the FTS/Hook/FHIP complex functions to promote vesicle trafficking and/or fusion via the homotypic vacuolar protein sorting complex.

Mouse (Murine) AKT Interacting Protein (AKTIP) interaction partners

  1. Ft1 protein is required for telomere maintenance.

  2. Primordial germ cell proliferation is impaired in Fused Toes mutant embryos.

  3. Owing to a deletion, six genes, including the entire IroquoisB (IrxB) gene cluster, are directly affected by the Ft mutation.

  4. Ft genes play an important role in dorsal-ventral patterning of the neural tube acting to define the extent of motor neuron generation

  5. Defects in brain patterning and head morphogenesis are caused by mutations in Fused toes gene.

AKTIP 抗原简介

Antigen Summary

The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.

Gene names and symbols associated with AKTIP

  • AKT interacting protein (AKTIP) 抗体
  • AKT interacting protein (aktip) 抗体
  • akt interacting protein (aktip) 抗体
  • AKT interacting protein S homeolog (aktip.S) 抗体
  • AKT interacting protein (Aktip) 抗体
  • thymoma viral proto-oncogene 1 interacting protein (Aktip) 抗体
  • aktip 抗体
  • AL023020 抗体
  • cb798 抗体
  • Fif 抗体
  • Ft 抗体
  • Ft1 抗体
  • Fts 抗体
  • fts-B 抗体
  • MGC133931 抗体
  • zgc:77699 抗体

Protein level used designations for AKTIP

AKT interacting protein , fused toes homolog , AKT-interacting protein , Fused toes protein homolog , fused toes protein homolog , AKT-interacting protein homolog B , fused toes protein

467979 Pan troglodytes
549957 Xenopus (Silurana) tropicalis
378716 Danio rerio
495128 Xenopus laevis
415720 Gallus gallus
64400 Homo sapiens
478126 Canis lupus familiaris
291906 Rattus norvegicus
100194893 Salmo salar
540462 Bos taurus
14339 Mus musculus